CHEMBL312982


SMILES O=C(c1ccc(F)cc1)C1CCN(CCN2C(=O)OCc3cc(CCCCN4CCOCC4)ccc32)CC1
InChIKey JDZYVIOTRKFEGM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 523.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 7.22 7.22 7.22 ChEMBL
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.0 7.0 7.0 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.03 6.03 6.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database