CHEMBL314372


SMILES COc1ccccc1N1CCN(CCCCc2ccc3c(c2)oc(=O)n3CCN2CCC(C(=O)c3ccc(F)cc3)CC2)CC1
InChIKey SMKCWLRQAIMCBO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 12
Molecular weight (Da) 614.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 7.12 7.12 7.12 ChEMBL
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 ChEMBL
D2 DRD2 Rat Dopamine A pKi 9.3 9.3 9.3 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database