CHEMBL315564


SMILES COc1ccc(Br)cc1C1=N[C@@H](CN2CCN(c3ccccc3)CC2)[C@@H](C)O1
InChIKey XHTCEJWQQIHAOR-UZLBHIALSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 443.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.46 5.89 6.32 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.48 6.01 6.54 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.0 5.3 5.6 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.68 5.12 5.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database