CHEMBL32145


SMILES C=CCN1CCc2c(cc(O)c(O)c2Br)C(c2ccccc2)C1
InChIKey KKZGFVAZUKHFAC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 373.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations D2

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 8.3 8.3 8.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.68 6.2 7.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 8.0 8.0 8.0 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 6.15 6.15 6.15 ChEMBL