CHEMBL322275


SMILES COc1cccc2c1CCCC2CCCN1CCN(c2ccccc2)CC1
InChIKey JGCUFOXBUYJGBX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 364.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.3 9.3 9.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pIC50 6.64 6.64 6.64 ChEMBL
α1A ADA1A Human Adrenoceptors A pIC50 7.37 7.37 7.37 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 6.96 6.97 7.01 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 9.3 9.34 9.44 ChEMBL