CHEMBL3287405


SMILES N#Cc1cnn2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc12
InChIKey JERZBICCWPTZQV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 443.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.03 6.03 6.03 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.24 8.24 8.24 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.31 6.31 6.31 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.82 8.82 8.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.24 9.37 9.49 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 7.91 7.92 7.92 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.96 6.96 6.96 ChEMBL