CHEMBL341474


SMILES CN1CCN(c2nc3cc(F)ccc3n3cccc23)CC1
InChIKey RYXJSAHVNPQLMV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 284.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.86 6.86 6.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pIC50 6.38 6.38 6.38 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 6.43 6.43 6.43 ChEMBL
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pIC50 6.91 6.91 6.91 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 6.86 6.86 6.86 ChEMBL