CHEMBL368816


SMILES N#Cc1ccc(S(=O)(=O)C2(F)CCN(CCc3ccc(F)cc3F)CC2)cc1
InChIKey RPBDTRSLAXVOEM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 408.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 8.88 8.88 8.88 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.83 5.83 5.83 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.57 8.57 8.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.06 6.06 6.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database