CHEMBL3765426


SMILES Cn1c(SCCCN2CCOC(c3ccc(C(F)(F)F)cc3)C2)nnc1-c1ccc(C(N)=O)cc1
InChIKey UDVBAIMSAZRJGM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 505.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.5 7.65 7.8 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.0 6.0 6.0 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.7 7.95 8.2 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.9 4.95 5.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database