CHEMBL392437


SMILES C#Cc1cccc(C(=O)NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c1
InChIKey UTCVZDGBUSLXBQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 429.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.4 7.4 7.4 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.08 9.08 9.08 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.62 7.72 7.82 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.14 6.14 6.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 8.46 8.46 8.46 ChEMBL