CHEMBL398175


SMILES Cc1cccc(-c2ccc(C(=O)NC/C=C/CN3CCN(c4cccc(Cl)c4Cl)CC3)cc2)n1
InChIKey IEANVAFYLZJSPC-NSCUHMNNSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 494.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.02 7.02 7.02 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.51 6.51 6.51 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.03 7.03 7.03 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.85 8.85 8.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.98 6.98 6.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 8.17 8.17 8.17 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.89 5.89 5.89 ChEMBL