CHEMBL40726


SMILES C[C@H](N)Cn1ccc2cc(F)c(F)cc21
InChIKey MYZDBEVPJGKIQS-ZETCQYMHSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 210.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 6.5 7.16 7.82 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.07 8.16 9.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.0 7.33 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pEC50 6.7 6.7 6.7 ChEMBL