CHEMBL433345


SMILES O=C(c1ccc(F)cc1)C1CCN(CCn2c(=O)sc3cc(CCCCN4CCOCC4)ccc32)CC1
InChIKey NSPAPURIGJZYJN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 525.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 9.22 9.22 9.22 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.0 7.0 7.0 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.16 6.16 6.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database