CHEMBL4515234


SMILES CCc1cccc(N2CCN(CC(F)CCNC(=O)c3cc4ccccc4[nH]3)CC2)c1Cl
InChIKey OTSVAHKQZLNXPN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 456.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.24 6.24 6.24 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.04 6.04 6.04 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.21 6.21 6.21 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.12 9.12 9.12 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.61 6.61 6.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 7.02 7.02 7.02 ChEMBL