CHEMBL4553059


SMILES CCc1cccc(N2CCN(CC(F)CCNC(=O)c3cc4ccccc4o3)CC2)c1Cl
InChIKey RPKWQRUGASWUBS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 457.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.33 6.33 6.33 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.93 6.93 6.93 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.61 8.61 8.61 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.48 6.48 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 6.46 6.46 6.46 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.35 6.35 6.35 ChEMBL