CHEMBL458718


SMILES CCCN(CCC)Cc1ccc(-c2ccc(CN(CCC)CCC)cc2)cc1
InChIKey CGLJDTUPXKUYST-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 13
Molecular weight (Da) 380.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 8.5 8.5 8.5 ChEMBL
H3 HRH3 Human Histamine A pKi 8.03 8.03 8.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Guinea pig Histamine A pEC50 5.47 5.47 5.47 ChEMBL