CHEMBL53510


SMILES Cc1ccc2c(c1O)-c1cccc3c1[C@@H](C2)N(C)CC3
InChIKey YGOZTDLAUVOPMF-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 265.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 5.01 6.07 6.42 ChEMBL
D2 DRD2 Rat Dopamine A pKi 4.94 5.46 5.97 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.67 8.68 9.35 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.97 5.97 5.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pEC50 7.26 7.26 7.26 ChEMBL