CHEMBL65641


SMILES COc1ccc(Br)cc1-c1nc(CNCC[C@@H]2CCN(Cc3ccccc3)C2)co1
InChIKey PUTIADDALKYHRM-LJQANCHMSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 469.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.05 5.05 5.05 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.77 6.77 6.77 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.92 6.92 6.92 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.96 5.96 5.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database