CHEMBL147431


SMILES Fc1ccc(CCN2CCC3(CCc4ccccc4O3)CC2)c(F)c1
InChIKey HMDHSUIMQILHRP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 343.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 9.14 9.14 9.14 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.35 6.35 6.35 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.62 8.62 8.62 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.12 6.12 6.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database