CHEMBL155486


SMILES O=C1CC(CN2CCC(c3noc4cc(F)ccc34)CC2)Cc2ccccc21
InChIKey BWEAUXJVFDVRAU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 378.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 8.57 8.57 8.57 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.08 6.53 6.98 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.53 8.29 8.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.67 7.03 7.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database