CHEMBL164185


SMILES Nc1ccccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3c1N2CCCS3
InChIKey GXSDXKGIICWKIF-FPOVZHCZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 407.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.7 6.73 6.76 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.68 8.95 9.22 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.82 8.02 8.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database