CHEMBL2308105


SMILES Fc1ccc(C(O[C@@H]2C[C@@H]3CC[C@H](C2)N3CCCCc2ccccc2)c2ccc(F)cc2)cc1
InChIKey FJCIWANMQSLZNY-WLNZHLEZSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 461.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 6.24 6.27 6.32 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.17 7.17 7.17 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.86 7.86 7.86 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.09 7.09 7.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database