CHEMBL2387253


SMILES COc1ccccc1N1CCN(CCCCOc2ccc3c(C)cc(=O)oc3c2)CC1
InChIKey LGHHLNJMNKPPHU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 422.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.32 8.32 8.32 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 8.1 8.1 8.1 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.85 8.85 8.85 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 10.92 10.92 10.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database