CHEMBL242434


SMILES CC(=O)OC(CCNC(=O)c1ccc(-c2ccccn2)cc1)CN1CCN(c2cccc(Cl)c2Cl)CC1
InChIKey KSTDXOPMADKXRO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 540.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.07 7.07 7.07 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.93 6.93 6.93 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.05 7.05 7.05 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.93 7.93 7.93 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.87 6.87 6.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 8.41 8.41 8.41 ChEMBL
D3 DRD3 Human Dopamine A pIC50 8.27 8.27 8.27 ChEMBL