GPCRdb

Ligand source activities (1 row/activity)

Potency
Affinity

Get vendors

Ligands					Receptor			Assay information							Chemical information
Sel. page	Common name	GPCRdb ID	#Vendors	Reference ligand	Fold selectivity (Potency)	# tested GPCRs (Potency)	Species	p-value (-log)	Type	Activity Relation	Activity Value	Assay Type	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI
	42637503	194134	0	None	100	3	Human	9.4	pEC50	=	9.4	Functional	Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14	ChEMBL	1238	19	12	15	2.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL558161	194134	0	None	100	3	Human	9.4	pEC50	=	9.4	Functional	Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14	ChEMBL	1238	19	12	15	2.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL563125	213959	0	None	-	1	Human	9.0	pEC50	=	9.0	Functional	Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](c2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm801314f
	42637069	193827	0	None	48	3	Human	8.4	pEC50	=	8.4	Functional	Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14	ChEMBL	1074	15	10	13	1.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL553655	193827	0	None	48	3	Human	8.4	pEC50	=	8.4	Functional	Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14	ChEMBL	1074	15	10	13	1.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL556949	213949	0	None	-	1	Human	7.5	pEC50	=	7.5	Functional	Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	68254010	165850	0	None	-1778	3	Human	5.2	pIC50	=	5.2	Functional	Antagonist activity at human SSTR1 expressed in CHO-K1 cell membranesAntagonist activity at human SSTR1 expressed in CHO-K1 cell membranes	ChEMBL	559	10	2	7	6.6	CCOc1cc(CN2CC[C@H]3C(Nc4nc5ccc(C(=O)O)cc5o4)CC[C@H]32)cc(OCC)c1-c1ccc(F)cc1	10.1021/acsmedchemlett.8b00305
	CHEMBL4277106	165850	0	None	-1778	3	Human	5.2	pIC50	=	5.2	Functional	Antagonist activity at human SSTR1 expressed in CHO-K1 cell membranesAntagonist activity at human SSTR1 expressed in CHO-K1 cell membranes	ChEMBL	559	10	2	7	6.6	CCOc1cc(CN2CC[C@H]3C(Nc4nc5ccc(C(=O)O)cc5o4)CC[C@H]32)cc(OCC)c1-c1ccc(F)cc1	10.1021/acsmedchemlett.8b00305
	145705877	216005	0	None	1	5	Human	8.1	pIC50	=	8.1	Functional	NoneNone	Drug Central	1047	17	9	11	3.4	NCCCC[C@@H]1NC(=O)[C@@H](CC2=CNC3=C2C=CC=C3)NC(=O)C(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=C(OCC3=CC=CC=C3)C=C2)NC1=O)OC(=O)NCCN)C1=CC=CC=C1	None
	2027	648	0	None	-398	5	Human	5.6	pIC50	=	5.6	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	11897676
	2003	634	0	None	-79	2	Human	6.4	pIC50	=	6.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8100350
	2006	891	0	None	-15	2	Rat	7.3	pIC50	=	7.3	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9166718
	2010	1344	0	None	-	1	Human	7.5	pIC50	=	7.5	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15658864
	2011	1342	0	None	-	1	Human	7.8	pIC50	=	7.8	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15658865
	2018	2946	22	None	-63	5	Human	8.0	pIC50	=	8	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15477717
	9941444	2946	22	None	-63	5	Human	8.0	pIC50	=	8	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15477717
	CHEMBL3349607	2946	22	None	-63	5	Human	8.0	pIC50	=	8	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15477717
	DB06663	2946	22	None	-63	5	Human	8.0	pIC50	=	8	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15477717
	2025	1250	0	None	-	1	Human	8.2	pIC50	=	8.2	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15658865
	2009	1341	0	None	-	1	Human	8.3	pIC50	=	8.3	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15658865
	2013	2140	0	None	-3	6	Human	8.6	pIC50	=	8.6	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	12450568
	2012	1343	0	None	1	4	Human	9.0	pIC50	=	9	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15658864
	2026	647	0	None	-31	5	Human	6.0	pIC50	None	6	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	11897676
	2019	3605	0	None	-50	4	Rat	8.4	pIC50	None	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9166718
	44386062	3605	0	None	-50	4	Rat	8.4	pIC50	None	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9166718
	CHEMBL440072	3605	0	None	-50	4	Rat	8.4	pIC50	None	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9166718
	2006	891	0	None	15	2	Human	8.5	pIC50	None	8.5	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011

Get vendors

Ligands					Receptor			Assay information							Chemical information
Sel. page	Common name	GPCRdb ID	#Vendors	Reference ligand	Fold selectivity (Affinity)	# tested GPCRs (Affinity)	Species	p-value (-log)	Type	Activity Relation	Activity Value	Assay Type	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI
	124168080	181242	0	None	-	0	Human	6.5	pEC50	=	6.5	Binding	Agonist activity at human SST1Agonist activity at human SST1	ChEMBL	507	6	2	7	4.4	Cc1cc(Cl)cc(-c2cnc3ncn(-c4cc(O)cc(F)c4)c(=O)c3c2CN(C)C[C@@H]2CCCN2)c1	10.1016/j.bmcl.2020.127496
	CHEMBL4778342	181242	0	None	-	0	Human	6.5	pEC50	=	6.5	Binding	Agonist activity at human SST1Agonist activity at human SST1	ChEMBL	507	6	2	7	4.4	Cc1cc(Cl)cc(-c2cnc3ncn(-c4cc(O)cc(F)c4)c(=O)c3c2CN(C)C[C@@H]2CCCN2)c1	10.1016/j.bmcl.2020.127496
	16129706	207277	36	None	-6	5	Human	9.9	pIC50	=	9.9	Binding	Binding affinity to Somatostatin receptor type 1 (unknown origin) by radioligand displacement assayBinding affinity to Somatostatin receptor type 1 (unknown origin) by radioligand displacement assay	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.bmc.2013.03.016
	CHEMBL1823872	207277	36	None	-6	5	Human	9.9	pIC50	=	9.9	Binding	Binding affinity to Somatostatin receptor type 1 (unknown origin) by radioligand displacement assayBinding affinity to Somatostatin receptor type 1 (unknown origin) by radioligand displacement assay	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.bmc.2013.03.016
	42637503	194134	0	None	-	0	Human	9.7	pIC50	=	9.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1238	19	12	15	2.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL558161	194134	0	None	-	0	Human	9.7	pIC50	=	9.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1238	19	12	15	2.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	45268875	193927	0	None	-	0	Human	9.1	pIC50	=	9.1	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1363	19	12	15	2.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3I)CSSC[C@@H](C(=O)N[C@@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL555977	193927	0	None	-	0	Human	9.1	pIC50	=	9.1	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1363	19	12	15	2.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3I)CSSC[C@@H](C(=O)N[C@@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL408338	210949	0	None	-	0	Human	9.0	pIC50	=	9.0	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm049520l
	45268875	193927	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Binding affinity to sst1 receptor in human prostate cancer cells by autoradiographyBinding affinity to sst1 receptor in human prostate cancer cells by autoradiography	ChEMBL	1363	19	12	15	2.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3I)CSSC[C@@H](C(=O)N[C@@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL555977	193927	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Binding affinity to sst1 receptor in human prostate cancer cells by autoradiographyBinding affinity to sst1 receptor in human prostate cancer cells by autoradiography	ChEMBL	1363	19	12	15	2.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3I)CSSC[C@@H](C(=O)N[C@@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	42637069	193827	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1074	15	10	13	1.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL553655	193827	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1074	15	10	13	1.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL409100	210989	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@@H]1CSSC[C@H](C(=O)O)NC(=O)[C@@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm010037+
	70689723	73605	0	None	-	0	Human	8.9	pIC50	=	8.9	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1170	16	9	12	4.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL2021559	73605	0	None	-	0	Human	8.9	pIC50	=	8.9	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1170	16	9	12	4.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	16129706	207277	36	None	-6	5	Human	8.8	pIC50	=	8.8	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	CHEMBL1823872	207277	36	None	-6	5	Human	8.8	pIC50	=	8.8	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	16129706	207277	36	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL1823872	207277	36	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL442494	212155	0	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm801205x
	16129706	207277	36	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm049519m
	CHEMBL1823872	207277	36	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm049519m
	CHEMBL262379	208783	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC1=O	10.1021/jm049520l
	CHEMBL425465	211577	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL3350911	209773	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	118718507	114846	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL	1050	14	11	12	3.4	CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)NC(C)(C)C)NC1=O	10.1021/jm970730q
	CHEMBL3349670	114846	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL	1050	14	11	12	3.4	CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)NC(C)(C)C)NC1=O	10.1021/jm970730q
	CHEMBL2079558	207440	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL3349505	209654	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(N)=O)[C@@H](C)O	10.1021/jm970730q
	CHEMBL3349506	209655	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](N)Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(N)=O)[C@@H](C)O	10.1021/jm970730q
	CHEMBL3349508	209657	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](N)Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(N)=O)[C@@H](C)O	10.1021/jm970730q
	CHEMBL3349597	209670	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(N)=O	10.1021/jm970730q
	CHEMBL3349608	209680	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cccnc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm970730q
	CHEMBL3349610	209681	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(C)(C)SSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	CHEMBL3349611	209682	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(=O)N[C@@H]1CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm970730q
	CHEMBL3349612	209683	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccccc2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	CHEMBL3349613	209684	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccccc2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	CHEMBL3349617	209687	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2cccnc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm970730q
	CHEMBL3349618	209688	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cccnc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm970730q
	CHEMBL3349663	209691	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2cccc(-c3ccccc3)c2)CSSC[C@@H](C(=O)N[C@@H](Cc2cccc(-c3ccccc3)c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL3349665	209693	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2cccc(-c3ccccc3)c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL3349668	209696	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2cccc(-c3ccccc3)c2)CSSC[C@@H](C(=O)N[C@@H](Cc2cccc(-c3ccccc3)c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL3349673	209700	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL3349674	209701	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](N)Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(N)=O	10.1021/jm970730q
	CHEMBL3349675	209702	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)N(C)C(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm970730q
	CHEMBL3349678	209705	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL3349680	209707	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](N)Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(N)=O	10.1021/jm970730q
	49865345	15720	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL	1043	18	13	12	0.7	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C/C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1	10.1021/jm1005868
	CHEMBL1223230	15720	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL	1043	18	13	12	0.7	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C/C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1	10.1021/jm1005868
	CHEMBL3349667	209695	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2cccc(-c3ccccc3)c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL412629	211255	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CNCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3349679	209706	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H]1CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm970730q
	CHEMBL408825	210977	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL2374244	208628	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]3CCC(=O)NCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL3349507	209656	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	162646037	178924	0	None	-	0	Human	5.0	pIC50	=	5.0	Binding	Displacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assayDisplacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assay	ChEMBL	1387	27	17	19	-2.0	CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(N)=O	10.1021/acs.jmedchem.6b00164
	CHEMBL4741230	178924	0	None	-	0	Human	5.0	pIC50	=	5.0	Binding	Displacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assayDisplacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assay	ChEMBL	1387	27	17	19	-2.0	CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(N)=O	10.1021/acs.jmedchem.6b00164
	25188780	12310	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	489	10	4	4	2.4	CC(=O)N[C@@H]1Cc2c([nH]c3ccccc23)CN([C@@H](CCCCN)C(=O)NCCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1185941	12310	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	489	10	4	4	2.4	CC(=O)N[C@@H]1Cc2c([nH]c3ccccc23)CN([C@@H](CCCCN)C(=O)NCCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL442605	12310	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	489	10	4	4	2.4	CC(=O)N[C@@H]1Cc2c([nH]c3ccccc23)CN([C@@H](CCCCN)C(=O)NCCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL540408	213927	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL3349666	209694	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2cccc(-c3ccccc3)c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL410047	211040	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm049519m
	CHEMBL408611	210966	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CN[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(CNC(C)C)cc2)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm049520l
	CHEMBL3350881	209748	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL3350895	209761	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL426698	211590	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)CNCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	122179477	120947	3	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Inhibition of SSTR1 receptor (unknown origin)Inhibition of SSTR1 receptor (unknown origin)	ChEMBL	525	5	3	9	3.2	CCn1cc([C@@]2(c3nn(C)c(=O)o3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1	10.1021/ml500514w
	CHEMBL3582336	120947	3	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Inhibition of SSTR1 receptor (unknown origin)Inhibition of SSTR1 receptor (unknown origin)	ChEMBL	525	5	3	9	3.2	CCn1cc([C@@]2(c3nn(C)c(=O)o3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1	10.1021/ml500514w
	CHEMBL1824049	207279	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	CHEMBL3122130	209352	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		C[C@H](NC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL500326	212330	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL554624	213939	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccccc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL556949	213949	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL387005	210646	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@H]3CCCCNC(=O)CC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049519m
	CHEMBL411002	211099	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049519m
	CHEMBL265120	208882	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CN[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(CNC(C)C)cc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm049520l
	CHEMBL411002	211099	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL1824050	207280	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	CHEMBL3349671	209698	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccc(-c3ccccc3)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL410144	211044	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL385811	210611	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL436887	211933	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL414749	211395	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL438776	212040	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL555737	213944	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL414716	211391	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL2079563	207442	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	CHEMBL446380	212186	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	44388108	161134	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1667	22	20	21	0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL413413	161134	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1667	22	20	21	0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL414692	211389	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL3351090	209788	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	44388133	166639	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1710	22	21	22	-0.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC(=O)NCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL429164	166639	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1710	22	21	22	-0.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC(=O)NCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL563461	213961	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@](C)([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL268205	208988	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL436887	211933	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL440083	212103	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCNC(N)=O)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3122129	209351	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)COCCOCCNC(=O)CN2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL437905	211980	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)N(C)C(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL3122124	209347	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		CCCC[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]1CSSC[C@@H](C(=O)N[C@@H](CO)C(=O)NCC(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL409952	211030	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL2373256	208618	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	25188220	12370	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	11	4	4	4.2	C[C@H](NC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O)c1ccccc1	10.1021/jm801205x
	CHEMBL1186489	12370	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	11	4	4	4.2	C[C@H](NC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O)c1ccccc1	10.1021/jm801205x
	CHEMBL466609	12370	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	11	4	4	4.2	C[C@H](NC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O)c1ccccc1	10.1021/jm801205x
	CHEMBL407858	210933	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	42637283	193832	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1334	20	11	14	5.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL553672	193832	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1334	20	11	14	5.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL559150	213957	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL265836	208911	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049519m
	CHEMBL386784	210635	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm049519m
	CHEMBL442494	212155	0	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Binding affinity to human sst1 by in vitro receptor autoradiography assayBinding affinity to human sst1 by in vitro receptor autoradiography assay	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/ml200032v
	CHEMBL442494	212155	0	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human sst1 receptor expressed in CHOK1 cells by autoradiographyDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human sst1 receptor expressed in CHOK1 cells by autoradiography	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm701445q
	CHEMBL1823873	207278	7	None	1	4	Human	8.6	pIC50	=	8.6	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	CHEMBL442494	212155	0	None	-6	5	Human	8.6	pIC50	=	8.6	Binding	Displacement of [125I](Leu8,D-Trp22,Tyr25)-SRIF28 from human sst1 receptorDisplacement of [125I](Leu8,D-Trp22,Tyr25)-SRIF28 from human sst1 receptor	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm070886i
	CHEMBL442494	212155	0	None	-6	5	Human	8.6	pIC50	=	8.6	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm1005868
	CHEMBL1909004	207320	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL559022	207320	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL413419	211307	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL263340	208813	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL1824051	207281	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	CHEMBL442494	212155	0	None	-6	5	Human	8.6	pIC50	=	8.6	Binding	Displacement of [125I][LTT]SRIF28 from human cloned sst1 receptor by autoradiographyDisplacement of [125I][LTT]SRIF28 from human cloned sst1 receptor by autoradiography	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm701618q
	CHEMBL442494	212155	0	None	-6	5	Human	8.5	pIC50	=	8.5	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm801314f
	45273131	193108	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1271	20	11	14	2.8	CN(C(=O)c1ccc2ccccc2c1)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(C(N)=O)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm801314f
	CHEMBL538451	193108	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1271	20	11	14	2.8	CN(C(=O)c1ccc2ccccc2c1)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(C(N)=O)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm801314f
	CHEMBL2311181	207752	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	156009460	177641	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1667	22	20	21	0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL4649897	177641	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1667	22	20	21	0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL439135	212068	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]3CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL3350897	209763	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](c1c[nH]c2ccccc12)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm030245x
	CHEMBL3350899	209765	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL3349614	209685	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	CHEMBL504248	212394	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@H]1CCSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL504457	212396	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL440066	212100	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL413442	211314	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)N(C)C(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	122179457	120927	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Binding affinity to somatostatin receptor type 1 (unknown origin)Binding affinity to somatostatin receptor type 1 (unknown origin)	ChEMBL	495	4	3	8	3.7	Cc1nc([C@]2(c3cnn(C)c3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)no1	10.1016/j.bmcl.2016.02.022
	CHEMBL3582317	120927	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Binding affinity to somatostatin receptor type 1 (unknown origin)Binding affinity to somatostatin receptor type 1 (unknown origin)	ChEMBL	495	4	3	8	3.7	Cc1nc([C@]2(c3cnn(C)c3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)no1	10.1016/j.bmcl.2016.02.022
	16737814	85068	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	551	11	4	4	3.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL227212	85068	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	551	11	4	4	3.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL504838	85068	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	551	11	4	4	3.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	16737814	85068	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptorDisplacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptor	ChEMBL	551	11	4	4	3.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm070246f
	CHEMBL227212	85068	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptorDisplacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptor	ChEMBL	551	11	4	4	3.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm070246f
	CHEMBL504838	85068	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptorDisplacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptor	ChEMBL	551	11	4	4	3.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm070246f
	10114	2509	18	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Displacement of [125I]SS-28 from human SSTR-1 transfected in CHO cells after 60 to 90 minsDisplacement of [125I]SS-28 from human SSTR-1 transfected in CHO cells after 60 to 90 mins	ChEMBL	494	4	3	7	4.3	Fc1ccc(cc1)c1cnc([nH]1)[C@H]1Cc2c3ccccc3[nH]c2[C@@](N1)(c1noc(n1)C)c1cnn(c1)C	10.1021/ml300063m
	56927659	2509	18	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Displacement of [125I]SS-28 from human SSTR-1 transfected in CHO cells after 60 to 90 minsDisplacement of [125I]SS-28 from human SSTR-1 transfected in CHO cells after 60 to 90 mins	ChEMBL	494	4	3	7	4.3	Fc1ccc(cc1)c1cnc([nH]1)[C@H]1Cc2c3ccccc3[nH]c2[C@@](N1)(c1noc(n1)C)c1cnn(c1)C	10.1021/ml300063m
	CHEMBL2204935	2509	18	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Displacement of [125I]SS-28 from human SSTR-1 transfected in CHO cells after 60 to 90 minsDisplacement of [125I]SS-28 from human SSTR-1 transfected in CHO cells after 60 to 90 mins	ChEMBL	494	4	3	7	4.3	Fc1ccc(cc1)c1cnc([nH]1)[C@H]1Cc2c3ccccc3[nH]c2[C@@](N1)(c1noc(n1)C)c1cnn(c1)C	10.1021/ml300063m
	CHEMBL405784	210822	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL407027	210876	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL3349669	209697	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL265615	208902	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	25187683	12330	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	627	12	4	4	5.2	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)C(c2ccccc2)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1186082	12330	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	627	12	4	4	5.2	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)C(c2ccccc2)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL448713	12330	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	627	12	4	4	5.2	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)C(c2ccccc2)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL410428	211063	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	49865343	15718	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL	1147	20	12	13	2.2	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C\C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(OC(=O)c3ccccc3)cc2)C(=O)N1	10.1021/jm1005868
	CHEMBL1223228	15718	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL	1147	20	12	13	2.2	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C\C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(OC(=O)c3ccccc3)cc2)C(=O)N1	10.1021/jm1005868
	CHEMBL384195	210562	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(=O)N2C)cc1	10.1021/jm049520l
	25187396	12560	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	475	9	4	4	2.4	CC(=O)N[C@@H]1Cc2c([nH]c3ccccc23)CN([C@@H](CCCCN)C(=O)NCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1187397	12560	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	475	9	4	4	2.4	CC(=O)N[C@@H]1Cc2c([nH]c3ccccc23)CN([C@@H](CCCCN)C(=O)NCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL501699	12560	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	475	9	4	4	2.4	CC(=O)N[C@@H]1Cc2c([nH]c3ccccc23)CN([C@@H](CCCCN)C(=O)NCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL262551	208786	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	44388036	159693	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1645	18	19	20	-0.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@@H](NC(=O)[C@H](Cc4ccc(O)cc4I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL411001	159693	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1645	18	19	20	-0.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@@H](NC(=O)[C@H](Cc4ccc(O)cc4I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL438576	212021	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	59568713	131593	11	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Inhibition of somatostatin receptor subtype 1 (unknown origin)Inhibition of somatostatin receptor subtype 1 (unknown origin)	ChEMBL	466	6	2	8	2.0	Cc1c([C@@H](O)CN2CCN(C[C@H](O)c3ccc4c(c3C)COC4=O)CC2)ccc2c1COC2=O	10.1021/acsmedchemlett.6b00122
	CHEMBL3696475	131593	11	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Inhibition of somatostatin receptor subtype 1 (unknown origin)Inhibition of somatostatin receptor subtype 1 (unknown origin)	ChEMBL	466	6	2	8	2.0	Cc1c([C@@H](O)CN2CCN(C[C@H](O)c3ccc4c(c3C)COC4=O)CC2)ccc2c1COC2=O	10.1021/acsmedchemlett.6b00122
	70683416	73604	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1170	16	9	12	4.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL2021544	73604	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1170	16	9	12	4.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL425090	211571	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL452157	212216	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030246p
	CHEMBL3350898	209764	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL452157	212216	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL452157	212216	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm200307v
	25187400	12570	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	537	10	4	4	3.7	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1187495	12570	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	537	10	4	4	3.7	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL504930	12570	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	537	10	4	4	3.7	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL452157	212216	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL452157	212216	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm801314f
	CHEMBL452157	212216	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm049519m
	CHEMBL265912	208916	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm010037+
	CHEMBL3350894	209760	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	44388134	140871	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1710	22	21	22	-0.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC(=O)NCCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL384072	140871	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1710	22	21	22	-0.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC(=O)NCCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	46902023	16842	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Displacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cellsDisplacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cells	ChEMBL	544	11	3	7	3.7	COC[C@H]1O[C@@H](OCc2ccc3ccccc3c2)[C@H](NC(=O)CCN)[C@@H](OCc2ccc3ccccc3c2)[C@@H]1O	10.1021/jm1002777
	CHEMBL1254476	16842	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Displacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cellsDisplacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cells	ChEMBL	544	11	3	7	3.7	COC[C@H]1O[C@@H](OCc2ccc3ccccc3c2)[C@H](NC(=O)CCN)[C@@H](OCc2ccc3ccccc3c2)[C@@H]1O	10.1021/jm1002777
	CHEMBL1907758	207314	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm030245x
	CHEMBL442494	212155	0	None	-6	5	Human	8.5	pIC50	=	8.5	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm701444y
	CHEMBL442494	212155	0	None	-6	5	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm049520l
	16151826	194173	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1555	21	18	21	-0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL558600	194173	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1555	21	18	21	-0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	44388121	166158	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1555	21	18	21	-0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL428295	166158	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1555	21	18	21	-0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL1908981	207316	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL539710	207316	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL1907758	207314	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 1 expressed in CHO-K1 cells; (n=5)In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 1 expressed in CHO-K1 cells; (n=5)	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm040794i
	CHEMBL386922	210644	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL1907758	207314	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm0302445
	CHEMBL1907758	207314	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm030243c
	CHEMBL409653	211018	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL414571	211386	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL447989	212193	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@@H]1SS[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL265846	208912	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC1=O	10.1021/jm010037+
	CHEMBL552013	213934	3	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL3349664	209692	0	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL2371059	208251	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		CNc1ccc(C(C(C)C)[C@@H]2NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC2=O)cc1	10.1021/jm030245x
	CHEMBL407125	210886	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)N(C)C(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL3350905	209768	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	CHEMBL3122123	209346	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		CCCC[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@H]1CSSC[C@@H](C(=O)N[C@@H](CO)C(=O)NCC(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL386023	210616	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL413441	211313	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3350884	209751	1	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O	10.1021/jm030245x
	CHEMBL428799	211713	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3350891	209758	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL437451	211962	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC1=O	10.1021/jm010037+
	CHEMBL404819	210777	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL413378	211305	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccc([N+](=O)[O-])cc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL1908984	207318	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL563124	207318	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL504395	212395	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@H]1CSS[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	42637136	194819	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1074	15	10	13	1.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL563462	194819	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1074	15	10	13	1.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	25189054	12580	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	685	11	4	6	3.0	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)C1=O	10.1021/jm801205x
	CHEMBL1187568	12580	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	685	11	4	6	3.0	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)C1=O	10.1021/jm801205x
	CHEMBL509513	12580	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	685	11	4	6	3.0	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)C1=O	10.1021/jm801205x
	25187955	12315	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	646	9	4	4	4.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCC3(CCc4ccccc43)CC2)C1=O	10.1021/jm801205x
	CHEMBL1185951	12315	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	646	9	4	4	4.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCC3(CCc4ccccc43)CC2)C1=O	10.1021/jm801205x
	CHEMBL443084	12315	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	646	9	4	4	4.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCC3(CCc4ccccc43)CC2)C1=O	10.1021/jm801205x
	CHEMBL3122127	209349	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		C[C@H](NC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)NCC(=O)N[C@H]1CSSC[C@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC1=O	10.1016/j.ejmech.2013.12.003
	25187679	12547	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	571	10	4	4	4.3	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)c2ccc(Cl)cc2)C1=O	10.1021/jm801205x
	CHEMBL1187340	12547	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	571	10	4	4	4.3	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)c2ccc(Cl)cc2)C1=O	10.1021/jm801205x
	CHEMBL499398	12547	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	571	10	4	4	4.3	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)c2ccc(Cl)cc2)C1=O	10.1021/jm801205x
	25189327	12572	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	601	11	4	4	4.7	NCCCC[C@@H](C(=O)NCc1cccc2ccccc12)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1187509	12572	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	601	11	4	4	4.7	NCCCC[C@@H](C(=O)NCc1cccc2ccccc12)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL505888	12572	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	601	11	4	4	4.7	NCCCC[C@@H](C(=O)NCc1cccc2ccccc12)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	118719101	114928	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1356	21	16	16	2.5	CNc1ccc(C(C(C)C)[C@@H]2NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC2=O)cc1	10.1021/jm030245x
	CHEMBL3350724	114928	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1356	21	16	16	2.5	CNc1ccc(C(C(C)C)[C@@H]2NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC2=O)cc1	10.1021/jm030245x
	CHEMBL1824052	207282	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	42637563	193828	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	989	12	9	12	2.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](Cc3ccc(O)cc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL553656	193828	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	989	12	9	12	2.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](Cc3ccc(O)cc3)NC2=O)cc1	10.1021/jm801314f
	44388124	158811	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1680	21	18	21	-0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL410048	158811	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1680	21	18	21	-0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	44325273	205567	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)	ChEMBL	554	7	2	4	5.4	NCCCC1CCCN2C(=O)[C@@H](Cc3c[nH]c4ccccc34)SCCN(Cc3cccc4ccccc34)C(=O)C12	10.1016/s0960-894x(00)00552-7
	CHEMBL93351	205567	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)	ChEMBL	554	7	2	4	5.4	NCCCC1CCCN2C(=O)[C@@H](Cc3c[nH]c4ccccc34)SCCN(Cc3cccc4ccccc34)C(=O)C12	10.1016/s0960-894x(00)00552-7
	CHEMBL2111257	207462	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@H](C)c2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm0302445
	CHEMBL3350357	209719	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand	ChEMBL		None	None	None		C[C@@H](c1ccc2ccccc2c1)[C@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm030246p
	CHEMBL525030	213845	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@H]1SSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL415144	211414	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3I)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL2369510	207876	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL1909006	207321	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccccc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL538948	207321	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccccc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC2=O)cc1	10.1021/jm801314f
	44368406	10155	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL	1022	9	11	12	1.1	C[C@@H]1NC(=O)N(C)[C@H](O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL1161332	10155	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL	1022	9	11	12	1.1	C[C@@H]1NC(=O)N(C)[C@H](O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL262790	208796	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL3350886	209753	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL269485	209036	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CCN(CC)C(=N)NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC1=O	10.1021/jm010037+
	CHEMBL2079559	207441	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2cccc(-c3ccccc3)c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	44388029	95994	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1659	18	18	20	0.0	CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@H]3CCCCCCNC(=O)CC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049519m
	CHEMBL262258	95994	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1659	18	18	20	0.0	CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@H]3CCCCCCNC(=O)CC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049519m
	CHEMBL2079626	207443	2	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	CHEMBL3350885	209752	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H]([C@H](C)c2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL2079558	207440	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL2079559	207441	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2cccc(-c3ccccc3)c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL407051	210877	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL406816	210866	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL1824055	207285	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030246p
	CHEMBL1824055	207285	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL1824055	207285	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm200307v
	CHEMBL216992	207593	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm049519m
	CHEMBL2369533	207877	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](CO)NC1=O	10.1021/jm010037+
	CHEMBL406197	210841	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	10577746	205511	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)	ChEMBL	514	8	3	4	4.6	NCCCC[C@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)SCCN(Cc2cccc3ccccc23)C1=O	10.1016/s0960-894x(00)00552-7
	CHEMBL92914	205511	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)	ChEMBL	514	8	3	4	4.6	NCCCC[C@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)SCCN(Cc2cccc3ccccc23)C1=O	10.1016/s0960-894x(00)00552-7
	CHEMBL3349677	209704	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	11563877	164157	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR1 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting methodDisplacement of [125I]somatostatin-14 (Tyr11) from human SSTR1 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting method	ChEMBL	668	9	3	5	5.7	Cc1cc(F)ccc1N1CCN(C(=O)N[C@@H](C(=O)Nc2cc(CN(C)C)ccc2OC(F)(F)F)[C@@H](C)c2c[nH]c3ccccc23)CC1=O	10.1016/j.bmc.2017.09.031
	CHEMBL4217405	164157	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR1 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting methodDisplacement of [125I]somatostatin-14 (Tyr11) from human SSTR1 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting method	ChEMBL	668	9	3	5	5.7	Cc1cc(F)ccc1N1CCN(C(=O)N[C@@H](C(=O)Nc2cc(CN(C)C)ccc2OC(F)(F)F)[C@@H](C)c2c[nH]c3ccccc23)CC1=O	10.1016/j.bmc.2017.09.031
	CHEMBL3350893	209759	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL413888	211338	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL412473	211237	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)[C@H](CO)N(C)C(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	42637210	193924	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	989	12	9	12	2.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](Cc3ccc(O)cc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL555956	193924	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	989	12	9	12	2.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](Cc3ccc(O)cc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL407120	210883	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3349676	209703	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccccc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL406559	210856	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)N(C)C(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	25187398	12327	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	12	4	4	4.0	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1186066	12327	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	12	4	4	4.0	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL448026	12327	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	12	4	4	4.0	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL503036	212379	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@@H]1CSS[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL415582	211432	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.	ChEMBL		None	None	None		C[C@@H](c1ccc2ccccc2c1)[C@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm0302445
	CHEMBL2371100	208257	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand	ChEMBL		None	None	None		C[C@@H](c1ccc2ccccc2c1)[C@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm030246p
	11468916	114951	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1137	15	14	14	0.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	CHEMBL3350910	114951	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1137	15	14	14	0.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	CHEMBL441202	212126	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	71461685	79122	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL	1644	25	18	20	1.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)CCc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL2114095	79122	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL	1644	25	18	20	1.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)CCc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	49865347	15722	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL	1197	20	12	13	3.4	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C\C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cccc3ccccc23)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(OC(=O)c3ccccc3)cc2)C(=O)N1	10.1021/jm1005868
	CHEMBL1223232	15722	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL	1197	20	12	13	3.4	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C\C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cccc3ccccc23)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(OC(=O)c3ccccc3)cc2)C(=O)N1	10.1021/jm1005868
	122179477	120947	3	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Displacement of [125I]SS-14 from human recombinant SSTR1 expressed in CHO cell membranes incubated for 60 to 90 mins by radioligand binding assayDisplacement of [125I]SS-14 from human recombinant SSTR1 expressed in CHO cell membranes incubated for 60 to 90 mins by radioligand binding assay	ChEMBL	525	5	3	9	3.2	CCn1cc([C@@]2(c3nn(C)c(=O)o3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1	10.1021/ml500514w
	CHEMBL3582336	120947	3	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Displacement of [125I]SS-14 from human recombinant SSTR1 expressed in CHO cell membranes incubated for 60 to 90 mins by radioligand binding assayDisplacement of [125I]SS-14 from human recombinant SSTR1 expressed in CHO cell membranes incubated for 60 to 90 mins by radioligand binding assay	ChEMBL	525	5	3	9	3.2	CCn1cc([C@@]2(c3nn(C)c(=O)o3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1	10.1021/ml500514w
	CHEMBL415143	211413	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)N(C)C(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL3349672	209699	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)N[C@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL263587	208823	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm049519m
	CHEMBL1908982	207317	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL552988	207317	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL411411	211127	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]3CCC(=O)NCC[C@@H](NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL1909003	207319	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CCCCCCC[C@@H]1NC(=O)[C@H](Cc2ccc(O)c(I)c2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(CNC(C)C)cc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC1=O	10.1021/jm801314f
	CHEMBL540721	207319	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CCCCCCC[C@@H]1NC(=O)[C@H](Cc2ccc(O)c(I)c2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(CNC(C)C)cc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC1=O	10.1021/jm801314f
	44388028	168191	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1645	18	19	20	-0.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@H](NC(=O)[C@H](Cc4ccc(O)cc4I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL437348	168191	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1645	18	19	20	-0.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@H](NC(=O)[C@H](Cc4ccc(O)cc4I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL3350912	209774	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	44388123	168609	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1681	21	18	21	0.2	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL440618	168609	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1681	21	18	21	0.2	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL2371051	208249	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2cccc3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm0302445
	CHEMBL1824056	207286	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm200307v
	44388120	177640	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1696	22	21	22	-1.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC(=O)NCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL4649895	177640	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1696	22	21	22	-1.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC(=O)NCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL414100	211351	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H]3CCCCNC(=O)CC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049519m
	44388037	160420	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1659	18	18	20	0.0	CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@@H]3CCCCCCNC(=O)CC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049519m
	CHEMBL411600	160420	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1659	18	18	20	0.0	CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@@H]3CCCCCCNC(=O)CC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049519m
	25188218	12442	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	11	4	4	4.2	C[C@@H](NC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O)c1ccccc1	10.1021/jm801205x
	CHEMBL1186753	12442	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	11	4	4	4.2	C[C@@H](NC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O)c1ccccc1	10.1021/jm801205x
	CHEMBL476240	12442	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	11	4	4	4.2	C[C@@H](NC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O)c1ccccc1	10.1021/jm801205x
	44388132	96827	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1696	22	21	22	-1.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC(=O)NCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL269023	96827	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1696	22	21	22	-1.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC(=O)NCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	11389178	114948	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1136	15	14	14	0.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL3350900	114948	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1136	15	14	14	0.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	44368019	10153	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL	1136	12	12	15	1.1	C[C@@H](O)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccc2)NC(=O)N(C(=O)c2ccccc2)C(=O)N(C)[C@H](O)NC(=O)[C@@H](N)CSSCCNC(=O)[C@@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL1161328	10153	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL	1136	12	12	15	1.1	C[C@@H](O)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccc2)NC(=O)N(C(=O)c2ccccc2)C(=O)N(C)[C@H](O)NC(=O)[C@@H](N)CSSCCNC(=O)[C@@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	162651887	179681	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Displacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assayDisplacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assay	ChEMBL	924	25	12	12	-0.1	CCC(NC(=O)[C@H](Cc1ccc(O)c([N+](=O)[O-])c1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](N)CC(N)=O)C(N)=O	10.1021/acs.jmedchem.6b00164
	CHEMBL4750625	179681	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Displacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assayDisplacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assay	ChEMBL	924	25	12	12	-0.1	CCC(NC(=O)[C@H](Cc1ccc(O)c([N+](=O)[O-])c1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](N)CC(N)=O)C(N)=O	10.1021/acs.jmedchem.6b00164
	CHEMBL427658	211604	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL411860	211204	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL264839	208876	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)N(C)C(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL438630	212026	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049519m
	CHEMBL412624	211254	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3349616	209686	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm970730q
	44388119	159818	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1682	22	21	22	-1.7	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC(=O)NCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL411109	159818	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1682	22	21	22	-1.7	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC(=O)NCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	25189325	12325	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	12	4	4	3.6	NCCCC[C@@H](C(=O)NCCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1186056	12325	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	12	4	4	3.6	NCCCC[C@@H](C(=O)NCCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL447455	12325	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	12	4	4	3.6	NCCCC[C@@H](C(=O)NCCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL268448	208999	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)N(C)C(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	11159133	114950	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1152	15	15	15	0.1	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	CHEMBL3350904	114950	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1152	15	15	15	0.1	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	25189052	12548	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	676	10	5	6	3.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCC(n3c(=O)[nH]c4ccccc43)CC2)C1=O	10.1021/jm801205x
	CHEMBL1187345	12548	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	676	10	5	6	3.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCC(n3c(=O)[nH]c4ccccc43)CC2)C1=O	10.1021/jm801205x
	CHEMBL499681	12548	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	676	10	5	6	3.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCC(n3c(=O)[nH]c4ccccc43)CC2)C1=O	10.1021/jm801205x
	CHEMBL455760	212245	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human sst1 receptor expressed in CHOK1 cells by autoradiographyDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human sst1 receptor expressed in CHOK1 cells by autoradiography	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2c[nH]c(C(=O)O)c2)CCSSCC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm701445q
	CHEMBL406373	210849	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.	ChEMBL		None	None	None		C[C@@H](c1ccc2ccccc2c1)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(I)cc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm0302445
	44388109	161196	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1653	22	20	21	-0.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL413924	161196	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1653	22	20	21	-0.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL505128	212407	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@@H]1SSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL436962	211942	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC1=O	10.1021/jm049519m
	CHEMBL3122128	209350	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)COCCOCCNC(=O)CN2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL414717	211392	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL408654	210969	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCNC(N)=O)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	42637632	59944	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1334	20	11	14	5.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL174206	59944	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1334	20	11	14	5.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL384855	210581	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	25187953	12565	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	725	10	4	6	3.8	CS(=O)(=O)N1CC2(CCN(C(=O)N[C@@H]3Cc4c([nH]c5ccccc45)CN([C@@H](CCCCN)C(=O)NCc4ccccc4)C3=O)CC2)c2ccccc21	10.1021/jm801205x
	CHEMBL1187458	12565	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	725	10	4	6	3.8	CS(=O)(=O)N1CC2(CCN(C(=O)N[C@@H]3Cc4c([nH]c5ccccc45)CN([C@@H](CCCCN)C(=O)NCc4ccccc4)C3=O)CC2)c2ccccc21	10.1021/jm801205x
	CHEMBL503379	12565	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	725	10	4	6	3.8	CS(=O)(=O)N1CC2(CCN(C(=O)N[C@@H]3Cc4c([nH]c5ccccc45)CN([C@@H](CCCCN)C(=O)NCc4ccccc4)C3=O)CC2)c2ccccc21	10.1021/jm801205x
	11457521	114947	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1136	15	14	14	0.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL3350892	114947	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1136	15	14	14	0.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	71460000	79234	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL	1644	25	18	20	1.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@H](NC(=O)CCc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL2115143	79234	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL	1644	25	18	20	1.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@H](NC(=O)CCc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	44368406	10155	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL	1022	9	11	12	1.1	C[C@@H]1NC(=O)N(C)[C@H](O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL1161332	10155	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL	1022	9	11	12	1.1	C[C@@H]1NC(=O)N(C)[C@H](O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL3350908	209771	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](c1c[nH]c2ccccc12)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm030245x
	25187685	12349	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	648	11	4	5	3.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)C2CCN(C(=O)c3ccccc3)CC2)C1=O	10.1021/jm801205x
	CHEMBL1186206	12349	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	648	11	4	5	3.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)C2CCN(C(=O)c3ccccc3)CC2)C1=O	10.1021/jm801205x
	CHEMBL454202	12349	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	648	11	4	5	3.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)C2CCN(C(=O)c3ccccc3)CC2)C1=O	10.1021/jm801205x
	16738359	136646	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	641	13	4	4	5.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CC(c2ccccc2)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL374833	136646	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	641	13	4	4	5.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CC(c2ccccc2)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL453938	136646	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	641	13	4	4	5.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CC(c2ccccc2)c2ccccc2)C1=O	10.1021/jm801205x
	16738359	136646	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptorDisplacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptor	ChEMBL	641	13	4	4	5.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CC(c2ccccc2)c2ccccc2)C1=O	10.1021/jm070246f
	CHEMBL374833	136646	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptorDisplacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptor	ChEMBL	641	13	4	4	5.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CC(c2ccccc2)c2ccccc2)C1=O	10.1021/jm070246f
	CHEMBL453938	136646	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptorDisplacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptor	ChEMBL	641	13	4	4	5.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CC(c2ccccc2)c2ccccc2)C1=O	10.1021/jm070246f
	CHEMBL440074	212101	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2I)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	44388107	158542	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1653	22	20	21	-0.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL409747	158542	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1653	22	20	21	-0.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL3349598	209671	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm970730q
	11642413	16904	0	None	-	0	Human	5.0	pIC50	=	5.0	Binding	Displacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cellsDisplacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cells	ChEMBL	544	11	3	7	3.9	CS[C@@H]1O[C@H](COCc2ccc(Cl)cc2)[C@@H](O)[C@@H](OCc2ccc3ccccc3c2)[C@H]1NC(=O)CCN	10.1021/jm1002777
	CHEMBL1254967	16904	0	None	-	0	Human	5.0	pIC50	=	5.0	Binding	Displacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cellsDisplacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cells	ChEMBL	544	11	3	7	3.9	CS[C@@H]1O[C@H](COCc2ccc(Cl)cc2)[C@@H](O)[C@@H](OCc2ccc3ccccc3c2)[C@H]1NC(=O)CCN	10.1021/jm1002777
	CHEMBL504087	212392	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@@H]1CCSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	24777672	94458	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Displacement of [125I](Leu8,D-Trp22,Tyr25)-SRIF28 from human sst1 receptorDisplacement of [125I](Leu8,D-Trp22,Tyr25)-SRIF28 from human sst1 receptor	ChEMBL	1027	18	12	11	1.0	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C\C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1	10.1021/jm070886i
	CHEMBL254210	94458	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Displacement of [125I](Leu8,D-Trp22,Tyr25)-SRIF28 from human sst1 receptorDisplacement of [125I](Leu8,D-Trp22,Tyr25)-SRIF28 from human sst1 receptor	ChEMBL	1027	18	12	11	1.0	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C\C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1	10.1021/jm070886i
	25188496	12413	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	476	9	3	5	2.5	COC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1186630	12413	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	476	9	3	5	2.5	COC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL473160	12413	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	476	9	3	5	2.5	COC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	42637137	194206	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1238	19	12	15	2.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL558935	194206	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1238	19	12	15	2.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	71460000	79234	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL	1644	25	18	20	1.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@H](NC(=O)CCc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL2115143	79234	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL	1644	25	18	20	1.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@H](NC(=O)CCc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3350890	209757	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	9849682	94498	0	None	8	10	Rat	9.7	pKd	=	9.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	523	2	1	5	2.9	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL254500	94498	0	None	8	10	Rat	9.7	pKd	=	9.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	523	2	1	5	2.9	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441671	154433	0	None	23988	2	Rat	9.7	pKd	=	9.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	542	4	0	10	1.8	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2Cc3c(cccc3OS(C)(=O)=O)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL401290	154433	0	None	23988	2	Rat	9.7	pKd	=	9.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	542	4	0	10	1.8	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2Cc3c(cccc3OS(C)(=O)=O)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44447075	94135	0	None	16218	2	Rat	9.6	pKd	=	9.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	507	2	1	7	3.5	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252032	94135	0	None	16218	2	Rat	9.6	pKd	=	9.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	507	2	1	7	3.5	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447049	94500	0	None	93325	2	Rat	9.6	pKd	=	9.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	3	1	5	3.4	CCn1c(N2CCN(C(=O)[C@@H]3C[C@@H]4c5cccc6[nH]c(Br)c(c56)C[C@H]4N(C)C3)CC2)cccc1=O	10.1016/j.bmcl.2007.12.030
	CHEMBL254505	94500	0	None	93325	2	Rat	9.6	pKd	=	9.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	3	1	5	3.4	CCn1c(N2CCN(C(=O)[C@@H]3C[C@@H]4c5cccc6[nH]c(Br)c(c56)C[C@H]4N(C)C3)CC2)cccc1=O	10.1016/j.bmcl.2007.12.030
	2019	3605	0	None	-4	10	Human	9.5	pKd	=	9.5	Binding	Displacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 minsDisplacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 mins	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.8b02036
	44386062	3605	0	None	-4	10	Human	9.5	pKd	=	9.5	Binding	Displacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 minsDisplacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 mins	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.8b02036
	CHEMBL440072	3605	0	None	-4	10	Human	9.5	pKd	=	9.5	Binding	Displacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 minsDisplacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 mins	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.8b02036
	44565159	193212	0	None	6	5	Rat	9.5	pKd	=	9.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	497	7	0	7	4.5	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL540705	193212	0	None	6	5	Rat	9.5	pKd	=	9.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	497	7	0	7	4.5	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	44447073	94101	0	None	3	10	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	534	2	1	6	3.8	CN1C[C@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL251835	94101	0	None	3	10	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	534	2	1	6	3.8	CN1C[C@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447076	94136	0	None	12302	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	551	2	1	7	3.6	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252033	94136	0	None	12302	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	551	2	1	7	3.6	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447048	154437	0	None	31622	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	3	1	5	3.3	CCn1c(N2CCN(C(=O)[C@@H]3C[C@@H]4c5cccc6[nH]c(Cl)c(c56)C[C@H]4N(C)C3)CC2)cccc1=O	10.1016/j.bmcl.2007.12.030
	CHEMBL401309	154437	0	None	31622	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	3	1	5	3.3	CCn1c(N2CCN(C(=O)[C@@H]3C[C@@H]4c5cccc6[nH]c(Cl)c(c56)C[C@H]4N(C)C3)CC2)cccc1=O	10.1016/j.bmcl.2007.12.030
	44447045	94497	0	None	125892	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	479	2	1	5	2.8	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL254499	94497	0	None	125892	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	479	2	1	5	2.8	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447071	153578	0	None	13182	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	490	2	1	6	3.7	CN1C[C@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL398526	153578	0	None	13182	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	490	2	1	6	3.7	CN1C[C@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441673	94085	0	None	9772	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	596	4	0	10	2.7	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2Cc3c(cccc3OS(=O)(=O)C(F)(F)F)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL251754	94085	0	None	9772	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	596	4	0	10	2.7	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2Cc3c(cccc3OS(=O)(=O)C(F)(F)F)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44441665	168556	0	None	9120	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	528	5	0	8	2.3	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OS(C)(=O)=O)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL440236	168556	0	None	9120	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	528	5	0	8	2.3	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OS(C)(=O)=O)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44447038	94222	0	None	16595	2	Rat	9.3	pKd	=	9.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	528	2	1	3	4.5	CN1C[C@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252618	94222	0	None	16595	2	Rat	9.3	pKd	=	9.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	528	2	1	3	4.5	CN1C[C@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	10162564	12418	0	None	9	8	Rat	9.2	pKd	=	9.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186652	12418	0	None	9	8	Rat	9.2	pKd	=	9.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL473763	12418	0	None	9	8	Rat	9.2	pKd	=	9.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441672	94084	0	None	3311	2	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	618	5	0	10	3.5	Cc1ccc(S(=O)(=O)Oc2cccc3c2C[C@H]2C[C@@H](C(=O)N4CCN(c5ccc6nsnc6n5)CC4)CN(C)[C@@H]2C3)cc1	10.1016/j.bmcl.2007.04.086
	CHEMBL251753	94084	0	None	3311	2	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	618	5	0	10	3.5	Cc1ccc(S(=O)(=O)Oc2cccc3c2C[C@H]2C[C@@H](C(=O)N4CCN(c5ccc6nsnc6n5)CC4)CN(C)[C@@H]2C3)cc1	10.1016/j.bmcl.2007.04.086
	44447069	94194	0	None	21379	2	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	484	2	1	3	4.4	CN1C[C@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252428	94194	0	None	21379	2	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	484	2	1	3	4.4	CN1C[C@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44564783	176341	0	None	10	4	Rat	9.2	pKd	=	9.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	484	8	0	5	4.8	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL461988	176341	0	None	10	4	Rat	9.2	pKd	=	9.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	484	8	0	5	4.8	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	2030	3602	7	None	7	10	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.078
	5311377	3602	7	None	7	10	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.078
	CHEMBL251541	3602	7	None	7	10	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.078
	2030	3602	7	None	7	10	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.086
	5311377	3602	7	None	7	10	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.086
	CHEMBL251541	3602	7	None	7	10	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.086
	44565112	12635	0	None	3	6	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	481	7	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187847	12635	0	None	3	6	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	481	7	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL523814	12635	0	None	3	6	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	481	7	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44447043	94469	0	None	10232	2	Rat	9.1	pKd	=	9.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	445	2	1	5	2.2	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL254288	94469	0	None	10232	2	Rat	9.1	pKd	=	9.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	445	2	1	5	2.2	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	17955460	176191	0	None	2	9	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	491	7	0	4	5.3	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL460542	176191	0	None	2	9	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	491	7	0	4	5.3	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	44441661	94043	0	None	7079	2	Rat	9.1	pKd	=	9.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	492	5	0	6	3.8	CC(C)Oc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL251542	94043	0	None	7079	2	Rat	9.1	pKd	=	9.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	492	5	0	6	3.8	CC(C)Oc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44441678	93605	0	None	12022	2	Rat	9.1	pKd	=	9.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	506	4	0	9	2.3	COc1ccc(C=O)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL248908	93605	0	None	12022	2	Rat	9.1	pKd	=	9.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	506	4	0	9	2.3	COc1ccc(C=O)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44564746	176377	0	None	7585	2	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	500	8	0	6	4.9	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL462336	176377	0	None	7585	2	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	500	8	0	6	4.9	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	44564815	189150	0	None	1905	2	Rat	9.0	pKd	=	9.0	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	498	9	0	5	5.2	CCN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL515907	189150	0	None	1905	2	Rat	9.0	pKd	=	9.0	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	498	9	0	5	5.2	CCN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44447042	94468	0	None	13489	2	Rat	9.0	pKd	=	9.0	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	542	3	1	3	4.9	CCN1C[C@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL254287	94468	0	None	13489	2	Rat	9.0	pKd	=	9.0	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	542	3	1	3	4.9	CCN1C[C@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447074	94102	0	None	2951	2	Rat	9.0	pKd	=	9.0	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	473	2	1	7	2.9	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL251836	94102	0	None	2951	2	Rat	9.0	pKd	=	9.0	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	473	2	1	7	2.9	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44565114	12512	0	None	-	1	Rat	9.0	pKd	=	9.0	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	480	7	0	6	3.9	CN(CCC(=O)N1CCN(c2ccc3nccn3n2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187144	12512	0	None	-	1	Rat	9.0	pKd	=	9.0	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	480	7	0	6	3.9	CN(CCC(=O)N1CCN(c2ccc3nccn3n2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL491497	12512	0	None	-	1	Rat	9.0	pKd	=	9.0	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	480	7	0	6	3.9	CN(CCC(=O)N1CCN(c2ccc3nccn3n2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441677	93604	0	None	5248	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	556	3	0	8	3.2	COc1ccc(Br)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL248907	93604	0	None	5248	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	556	3	0	8	3.2	COc1ccc(Br)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	23656025	93647	0	None	8511	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	450	4	1	6	2.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL249113	93647	0	None	8511	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	450	4	1	6	2.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44441670	154095	0	None	3981	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	554	5	0	8	4.0	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2Cc3c(cccc3OCc3ccccc3)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL399464	154095	0	None	3981	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	554	5	0	8	4.0	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2Cc3c(cccc3OCc3ccccc3)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44447073	94101	0	None	-3	10	Human	8.9	pKd	=	8.9	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	534	2	1	6	3.8	CN1C[C@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL251835	94101	0	None	-3	10	Human	8.9	pKd	=	8.9	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	534	2	1	6	3.8	CN1C[C@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441669	93567	0	None	4677	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	478	3	0	8	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL248715	93567	0	None	4677	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	478	3	0	8	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441669	93567	0	None	4677	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	478	3	0	8	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL248715	93567	0	None	4677	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	478	3	0	8	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44447064	153824	0	None	7079	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	3	1	5	4.0	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL398712	153824	0	None	7079	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	3	1	5	4.0	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441899	153789	0	None	8511	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccc4[N+](=O)[O-])CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL398681	153789	0	None	8511	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccc4[N+](=O)[O-])CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441900	93851	0	None	5128	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc([N+](=O)[O-])c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250498	93851	0	None	5128	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc([N+](=O)[O-])c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44447066	94163	0	None	5370	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	3	1	5	4.1	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252229	94163	0	None	5370	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	3	1	5	4.1	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441659	154130	0	None	7762	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	538	4	0	7	2.7	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2Cc3c(cccc3OS(=O)(=O)C(F)(F)F)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL399658	154130	0	None	7762	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	538	4	0	7	2.7	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2Cc3c(cccc3OS(=O)(=O)C(F)(F)F)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44441666	154170	0	None	2290	2	Rat	8.8	pKd	=	8.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	582	5	0	8	3.2	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OS(=O)(=O)C(F)(F)F)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL399843	154170	0	None	2290	2	Rat	8.8	pKd	=	8.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	582	5	0	8	3.2	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OS(=O)(=O)C(F)(F)F)C[C@H]21	10.1016/j.bmcl.2007.04.086
	17955460	176191	0	None	-2	9	Human	8.8	pKd	=	8.8	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	491	7	0	4	5.3	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL460542	176191	0	None	-2	9	Human	8.8	pKd	=	8.8	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	491	7	0	4	5.3	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	44564859	12600	0	None	-	1	Rat	8.8	pKd	=	8.8	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2ccc(Cl)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187680	12600	0	None	-	1	Rat	8.8	pKd	=	8.8	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2ccc(Cl)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL515113	12600	0	None	-	1	Rat	8.8	pKd	=	8.8	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2ccc(Cl)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441884	93944	0	None	2041	2	Rat	8.8	pKd	=	8.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	461	3	0	7	2.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nonc5c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250922	93944	0	None	2041	2	Rat	8.8	pKd	=	8.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	461	3	0	7	2.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nonc5c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	9849682	94498	0	None	-8	10	Human	8.8	pKd	=	8.8	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	523	2	1	5	2.9	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL254500	94498	0	None	-8	10	Human	8.8	pKd	=	8.8	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	523	2	1	5	2.9	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441919	154220	0	None	3019	2	Rat	8.8	pKd	=	8.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	542	5	0	8	2.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4S(C)(=O)=O)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400137	154220	0	None	3019	2	Rat	8.8	pKd	=	8.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	542	5	0	8	2.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4S(C)(=O)=O)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564907	12410	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	6.2	CN(CCC(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186613	12410	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	6.2	CN(CCC(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL472751	12410	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	6.2	CN(CCC(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44565010	12514	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	457	7	0	3	5.0	CN(CCC(=O)N1CCN(c2ccc(F)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187146	12514	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	457	7	0	3	5.0	CN(CCC(=O)N1CCN(c2ccc(F)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL491507	12514	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	457	7	0	3	5.0	CN(CCC(=O)N1CCN(c2ccc(F)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441897	93775	0	None	3715	2	Rat	8.7	pKd	=	8.7	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	444	3	0	5	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccc4C#N)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL249930	93775	0	None	3715	2	Rat	8.7	pKd	=	8.7	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	444	3	0	5	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccc4C#N)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	2030	3602	7	None	-13	10	Human	8.0	pKd	=	8.0	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.086
	5311377	3602	7	None	-13	10	Human	8.0	pKd	=	8.0	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.086
	CHEMBL251541	3602	7	None	-13	10	Human	8.0	pKd	=	8.0	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.086
	44441886	154212	0	None	398	2	Rat	8.0	pKd	=	8.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	477	3	0	7	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400099	154212	0	None	398	2	Rat	8.0	pKd	=	8.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	477	3	0	7	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	46880580	5457	0	None	-346	2	Human	6.0	pKd	=	6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(CC(C)CN2CC3CCCCC3C(C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076657	5457	0	None	-346	2	Human	6.0	pKd	=	6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(CC(C)CN2CC3CCCCC3C(C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL385409	210592	0	None	-97	4	Human	6.0	pKd	=	6	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	CHEMBL437093	211947	0	None	-16	5	Human	6.0	pKd	=	6	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N(C)[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	CHEMBL438471	212015	0	None	-125	4	Human	6.0	pKd	=	6	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N(C)[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	46880574	6005	0	None	-1	2	Human	7.0	pKd	=	7.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	494	7	0	7	3.6	CC(Cc1ccc2c(c1)OCO2)CN1CCCC(C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1080734	6005	0	None	-1	2	Human	7.0	pKd	=	7.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	494	7	0	7	3.6	CC(Cc1ccc2c(c1)OCO2)CN1CCCC(C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C1	10.1016/j.bmcl.2010.01.063
	44441871	93821	0	None	190	2	Rat	7.0	pKd	=	7.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	488	3	0	5	3.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(F)(F)F)cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250313	93821	0	None	190	2	Rat	7.0	pKd	=	7.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	488	3	0	5	3.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(F)(F)F)cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441873	93978	0	None	63	2	Rat	7.0	pKd	=	7.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	526	6	0	6	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(OCc5ccccc5)n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251116	93978	0	None	63	2	Rat	7.0	pKd	=	7.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	526	6	0	6	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(OCc5ccccc5)n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441932	94012	0	None	4	2	Rat	5.0	pKd	=	5.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	343	2	1	4	1.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCNCC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251301	94012	0	None	4	2	Rat	5.0	pKd	=	5.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	343	2	1	4	1.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCNCC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441918	166307	0	None	44	2	Rat	7.0	pKd	=	7.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	532	4	0	6	4.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(F)(F)F)cc4[N+](=O)[O-])CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL428583	166307	0	None	44	2	Rat	7.0	pKd	=	7.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	532	4	0	6	4.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(F)(F)F)cc4[N+](=O)[O-])CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564703	189893	0	None	446	2	Rat	7.9	pKd	=	7.9	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	510	8	0	5	5.3	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2C=Cc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL517921	189893	0	None	446	2	Rat	7.9	pKd	=	7.9	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	510	8	0	5	5.3	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2C=Cc2ccccc21	10.1016/j.bmcl.2009.01.072
	44447029	170452	0	None	-	1	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	535	5	1	4	4.8	CCCCN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL445673	170452	0	None	-	1	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	535	5	1	4	4.8	CCCCN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	46865536	11799	0	None	-151	7	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	553	6	0	6	5.2	C[C@@H](Cc1ccc2nsnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076623	11799	0	None	-151	7	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	553	6	0	6	5.2	C[C@@H](Cc1ccc2nsnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1182658	11799	0	None	-151	7	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	553	6	0	6	5.2	C[C@@H](Cc1ccc2nsnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	44564745	176376	0	None	478	2	Rat	7.9	pKd	=	7.9	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	516	8	0	6	5.3	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2Sc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL462335	176376	0	None	478	2	Rat	7.9	pKd	=	7.9	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	516	8	0	6	5.3	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2Sc2ccccc21	10.1016/j.bmcl.2009.01.072
	44447009	94317	0	None	-	1	Rat	7.9	pKd	=	7.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	449	2	1	4	3.5	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL253234	94317	0	None	-	1	Rat	7.9	pKd	=	7.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	449	2	1	4	3.5	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	46880573	6004	0	None	-1	2	Human	6.9	pKd	=	6.9	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	510	6	0	5	5.2	O=C(C1CCCN(CCC2c3ccccc3-c3ccccc32)C1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1	10.1016/j.bmcl.2010.01.063
	CHEMBL1080733	6004	0	None	-1	2	Human	6.9	pKd	=	6.9	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	510	6	0	5	5.2	O=C(C1CCCN(CCC2c3ccccc3-c3ccccc32)C1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1	10.1016/j.bmcl.2010.01.063
	CHEMBL407209	210890	1	None	-1949	4	Human	5.9	pKd	=	5.9	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N(C)[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	CHEMBL384836	210580	0	None	-74	5	Human	5.9	pKd	=	5.9	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1C)C(N)=O	10.1021/jm000361p
	44564814	179447	0	None	602	2	Rat	7.9	pKd	=	7.9	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	486	10	0	5	4.8	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC(c1ccccc1)c1ccccc1	10.1016/j.bmcl.2009.01.072
	CHEMBL474752	179447	0	None	602	2	Rat	7.9	pKd	=	7.9	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	486	10	0	5	4.8	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC(c1ccccc1)c1ccccc1	10.1016/j.bmcl.2009.01.072
	44441680	93646	0	None	11	2	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@@H]1C[C@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL249112	93646	0	None	11	2	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@@H]1C[C@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL2370166	208050	0	None	-977	5	Human	4.9	pKd	=	4.9	Binding	In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.	ChEMBL		None	None	None		C[C@@H](c1ccccc1)N1CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCNC(=O)[C@@H](N)Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C1=O	10.1021/jm970393l
	46865535	5449	0	None	-407	7	Human	5.9	pKd	=	5.9	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	550	6	0	5	5.7	Cc1nc2cc(C[C@H](C)CN3C[C@@H](C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)[C@H]4CCCC[C@H]4C3)ccc2o1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076622	5449	0	None	-407	7	Human	5.9	pKd	=	5.9	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	550	6	0	5	5.7	Cc1nc2cc(C[C@H](C)CN3C[C@@H](C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)[C@H]4CCCC[C@H]4C3)ccc2o1	10.1016/j.bmcl.2010.01.063
	44447006	94315	0	None	1258	2	Rat	7.9	pKd	=	7.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	415	2	1	4	2.9	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL253232	94315	0	None	1258	2	Rat	7.9	pKd	=	7.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	415	2	1	4	2.9	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447034	154207	0	None	-	1	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	5	1	5	3.7	COCCN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL400066	154207	0	None	-	1	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	5	1	5	3.7	COCCN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441667	154390	0	None	457	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	459	3	0	6	2.9	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(C#N)cccc3C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL401091	154390	0	None	457	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	459	3	0	6	2.9	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(C#N)cccc3C[C@H]21	10.1016/j.bmcl.2007.04.086
	44441906	93902	0	None	57	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	461	4	0	5	3.3	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(C)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250705	93902	0	None	57	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	461	4	0	5	3.3	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(C)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441909	93773	0	None	10	2	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	462	4	1	5	2.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(N)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL249892	93773	0	None	10	2	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	462	4	1	5	2.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(N)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	46865536	11799	0	None	-199	7	Human	5.8	pKd	=	5.8	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	553	6	0	6	5.2	C[C@@H](Cc1ccc2nsnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076623	11799	0	None	-199	7	Human	5.8	pKd	=	5.8	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	553	6	0	6	5.2	C[C@@H](Cc1ccc2nsnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1182658	11799	0	None	-199	7	Human	5.8	pKd	=	5.8	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	553	6	0	6	5.2	C[C@@H](Cc1ccc2nsnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	44441660	94016	0	None	204	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	390	2	0	4	2.5	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2Cc3ccccc3C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL251335	94016	0	None	204	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	390	2	0	4	2.5	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2Cc3ccccc3C[C@H]21	10.1016/j.bmcl.2007.04.086
	44447014	94375	0	None	338	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	541	2	1	4	3.5	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(I)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL253653	94375	0	None	338	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	541	2	1	4	3.5	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(I)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441908	93939	0	None	91	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	477	4	0	6	2.9	COC(=O)c1ccc(N2CCN(C(=O)[C@@H]3C[C@@H]4Cc5c(cccc5OC)C[C@H]4N(C)C3)CC2)cc1	10.1016/j.bmcl.2007.04.078
	CHEMBL250900	93939	0	None	91	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	477	4	0	6	2.9	COC(=O)c1ccc(N2CCN(C(=O)[C@@H]3C[C@@H]4Cc5c(cccc5OC)C[C@H]4N(C)C3)CC2)cc1	10.1016/j.bmcl.2007.04.078
	46880853	5475	0	None	-147	2	Human	5.8	pKd	=	5.8	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	536	6	0	5	5.4	C[C@@H](Cc1ccc2ocnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076718	5475	0	None	-147	2	Human	5.8	pKd	=	5.8	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	536	6	0	5	5.4	C[C@@H](Cc1ccc2ocnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	44447026	94131	0	None	46	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	479	2	2	4	3.3	O=C([C@H]1CN[C@@H]2Cc3c(Br)[nH]c4cccc(c34)[C@H]2C1)N1CCN(c2ccccn2)CC1	10.1016/j.bmcl.2007.12.030
	CHEMBL252002	94131	0	None	46	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	479	2	2	4	3.3	O=C([C@H]1CN[C@@H]2Cc3c(Br)[nH]c4cccc(c34)[C@H]2C1)N1CCN(c2ccccn2)CC1	10.1016/j.bmcl.2007.12.030
	44441910	93774	0	None	11	2	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	518	6	0	5	3.6	CCN(CC)C(=O)c1ccc(N2CCN(C(=O)[C@@H]3C[C@@H]4Cc5c(cccc5OC)C[C@H]4N(C)C3)CC2)cc1	10.1016/j.bmcl.2007.04.078
	CHEMBL249893	93774	0	None	11	2	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	518	6	0	5	3.6	CCN(CC)C(=O)c1ccc(N2CCN(C(=O)[C@@H]3C[C@@H]4Cc5c(cccc5OC)C[C@H]4N(C)C3)CC2)cc1	10.1016/j.bmcl.2007.04.078
	44441658	94015	0	None	588	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	420	3	0	5	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251334	94015	0	None	588	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	420	3	0	5	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441658	94015	0	None	588	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	420	3	0	5	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL251334	94015	0	None	588	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	420	3	0	5	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44564903	12428	0	None	-	1	Rat	7.8	pKd	=	7.8	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2cccc(Cl)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186691	12428	0	None	-	1	Rat	7.8	pKd	=	7.8	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2cccc(Cl)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL474745	12428	0	None	-	1	Rat	7.8	pKd	=	7.8	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2cccc(Cl)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441890	94013	0	None	1047	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	437	3	0	4	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccc4F)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251311	94013	0	None	1047	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	437	3	0	4	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccc4F)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44447032	94412	0	None	-	1	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	549	5	1	4	5.1	CC(C)CCN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL253880	94412	0	None	-	1	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	549	5	1	4	5.1	CC(C)CCN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44564702	189266	0	None	190	2	Rat	7.7	pKd	=	7.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	512	8	0	5	4.9	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2CCc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL516837	189266	0	None	190	2	Rat	7.7	pKd	=	7.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	512	8	0	5	4.9	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2CCc2ccccc21	10.1016/j.bmcl.2009.01.072
	44441662	94044	0	None	416	2	Rat	7.7	pKd	=	7.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	450	3	1	6	2.7	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(O)cccc3C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL251543	94044	0	None	416	2	Rat	7.7	pKd	=	7.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	450	3	1	6	2.7	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(O)cccc3C[C@H]21	10.1016/j.bmcl.2007.04.086
	44447078	94167	0	None	2	7	Rat	6.7	pKd	=	6.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	534	2	1	6	3.8	CN1C[C@@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252232	94167	0	None	2	7	Rat	6.7	pKd	=	6.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	534	2	1	6	3.8	CN1C[C@@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	44441867	93797	0	None	9	2	Rat	5.7	pKd	=	5.7	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	420	3	0	5	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccncc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250111	93797	0	None	9	2	Rat	5.7	pKd	=	5.7	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	420	3	0	5	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccncc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44447052	154400	0	None	112	2	Rat	7.7	pKd	=	7.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	448	2	1	3	4.1	CN1C[C@H](C(=O)N2CCN(c3ccc(Cl)cc3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL401130	154400	0	None	112	2	Rat	7.7	pKd	=	7.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	448	2	1	3	4.1	CN1C[C@H](C(=O)N2CCN(c3ccc(Cl)cc3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	46880856	5471	0	None	-66	2	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	539	8	1	5	5.1	CCNc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076711	5471	0	None	-66	2	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	539	8	1	5	5.1	CCNc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	44447077	94166	0	None	-4	7	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	523	2	1	5	2.9	CN1C[C@@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252231	94166	0	None	-4	7	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	523	2	1	5	2.9	CN1C[C@@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	44565159	193212	0	None	-6	5	Human	8.7	pKd	=	8.7	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	497	7	0	7	4.5	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL540705	193212	0	None	-6	5	Human	8.7	pKd	=	8.7	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	497	7	0	7	4.5	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	44565064	12509	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	470	7	0	5	3.6	CN(CCC(=O)N1CCN(c2cccc(=O)n2C)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187127	12509	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	470	7	0	5	3.6	CN(CCC(=O)N1CCN(c2cccc(=O)n2C)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL491144	12509	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	470	7	0	5	3.6	CN(CCC(=O)N1CCN(c2cccc(=O)n2C)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44447019	94411	0	None	3548	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	461	3	1	5	3.6	CSc1[nH]c2cccc3c2c1C[C@@H]1[C@@H]3C[C@@H](C(=O)N2CCN(c3ccccn3)CC2)CN1C	10.1016/j.bmcl.2007.12.030
	CHEMBL253879	94411	0	None	3548	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	461	3	1	5	3.6	CSc1[nH]c2cccc3c2c1C[C@@H]1[C@@H]3C[C@@H](C(=O)N2CCN(c3ccccn3)CC2)CN1C	10.1016/j.bmcl.2007.12.030
	44565112	12635	0	None	-3	6	Human	8.6	pKd	=	8.6	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	481	7	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187847	12635	0	None	-3	6	Human	8.6	pKd	=	8.6	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	481	7	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL523814	12635	0	None	-3	6	Human	8.6	pKd	=	8.6	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	481	7	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441885	93979	0	None	3630	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	477	3	0	7	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5nsnc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251120	93979	0	None	3630	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	477	3	0	7	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5nsnc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	23656026	93817	0	None	-3	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	455	3	0	4	3.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250304	93817	0	None	-3	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	455	3	0	4	3.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441916	154219	0	None	5888	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	462	3	0	5	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(F)c4C#N)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400136	154219	0	None	5888	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	462	3	0	5	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(F)c4C#N)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	9871544	14086	1	None	-416	11	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076624	14086	1	None	-416	11	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1198948	14086	1	None	-416	11	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	44441921	93903	0	None	165	2	Rat	6.7	pKd	=	6.7	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	434	3	0	5	2.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCCN(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250713	93903	0	None	165	2	Rat	6.7	pKd	=	6.7	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	434	3	0	5	2.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCCN(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44565068	12624	0	None	-	1	Rat	7.7	pKd	=	7.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	440	7	0	4	4.3	CN(CCC(=O)N1CCN(c2ccncc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187808	12624	0	None	-	1	Rat	7.7	pKd	=	7.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	440	7	0	4	4.3	CN(CCC(=O)N1CCN(c2ccncc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL522135	12624	0	None	-	1	Rat	7.7	pKd	=	7.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	440	7	0	4	4.3	CN(CCC(=O)N1CCN(c2ccncc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441902	154324	0	None	562	2	Rat	7.6	pKd	=	7.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	487	3	0	4	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(C(F)(F)F)c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400709	154324	0	None	562	2	Rat	7.6	pKd	=	7.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	487	3	0	4	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(C(F)(F)F)c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564905	12409	0	None	-	1	Rat	7.6	pKd	=	7.6	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2ccccc2Cl)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186612	12409	0	None	-	1	Rat	7.6	pKd	=	7.6	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2ccccc2Cl)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL472750	12409	0	None	-	1	Rat	7.6	pKd	=	7.6	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2ccccc2Cl)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	46880581	5458	0	None	-21	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(CC(C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076658	5458	0	None	-21	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(CC(C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	46880855	5470	0	None	-165	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	540	8	0	5	5.0	CCOc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076710	5470	0	None	-165	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	540	8	0	5	5.0	CCOc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	44447037	94221	0	None	-	1	Rat	5.6	pKd	=	5.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	5	2	5	3.4	O=C([C@@H]1C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]2N(CCCO)C1)N1CCN(c2ccccn2)CC1	10.1016/j.bmcl.2007.12.030
	CHEMBL252617	94221	0	None	-	1	Rat	5.6	pKd	=	5.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	5	2	5	3.4	O=C([C@@H]1C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]2N(CCCO)C1)N1CCN(c2ccccn2)CC1	10.1016/j.bmcl.2007.12.030
	44447016	94376	0	None	35	2	Rat	6.6	pKd	=	6.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	431	2	2	5	2.6	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(O)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL253654	94376	0	None	35	2	Rat	6.6	pKd	=	6.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	431	2	2	5	2.6	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(O)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	46880576	5453	0	None	-1	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.7	CC(Cc1ccc2c(c1)OCO2)CN1C[C@@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2CCCC[C@@H]21	10.1016/j.bmcl.2010.01.063
	CHEMBL1076653	5453	0	None	-1	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.7	CC(Cc1ccc2c(c1)OCO2)CN1C[C@@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2CCCC[C@@H]21	10.1016/j.bmcl.2010.01.063
	44441663	94042	0	None	660	2	Rat	7.6	pKd	=	7.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	534	4	0	7	3.9	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OC(=O)C(C)(C)C)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL251529	94042	0	None	660	2	Rat	7.6	pKd	=	7.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	534	4	0	7	3.9	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OC(=O)C(C)(C)C)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44441923	93904	0	None	85	2	Rat	6.6	pKd	=	6.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	478	4	0	6	3.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250715	93904	0	None	85	2	Rat	6.6	pKd	=	6.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	478	4	0	6	3.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	20597810	5469	0	None	-245	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	547	6	0	5	5.2	C[C@@H](Cc1ccc2nccnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076709	5469	0	None	-245	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	547	6	0	5	5.2	C[C@@H](Cc1ccc2nccnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	44447023	94096	0	None	6	2	Rat	5.6	pKd	=	5.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	477	3	1	5	2.6	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c([S+](C)[O-])c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL251801	94096	0	None	6	2	Rat	5.6	pKd	=	5.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	477	3	1	5	2.6	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c([S+](C)[O-])c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441879	93907	0	None	75	2	Rat	7.6	pKd	=	7.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	470	3	0	5	3.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5ccccc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250724	93907	0	None	75	2	Rat	7.6	pKd	=	7.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	470	3	0	5	3.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5ccccc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564786	176232	0	None	60	2	Rat	6.6	pKd	=	6.6	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	446	8	0	5	4.0	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCc1ccc2ccccc2c1	10.1016/j.bmcl.2009.01.072
	CHEMBL460934	176232	0	None	60	2	Rat	6.6	pKd	=	6.6	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	446	8	0	5	4.0	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCc1ccc2ccccc2c1	10.1016/j.bmcl.2009.01.072
	44441903	93900	0	None	18	2	Rat	6.6	pKd	=	6.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	487	3	0	4	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(F)(F)F)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250703	93900	0	None	18	2	Rat	6.6	pKd	=	6.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	487	3	0	4	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(F)(F)F)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441880	168650	0	None	19	2	Rat	6.5	pKd	=	6.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	470	3	0	5	3.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cc5ccccc5cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL440962	168650	0	None	19	2	Rat	6.5	pKd	=	6.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	470	3	0	5	3.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cc5ccccc5cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564744	176359	0	None	630	2	Rat	7.5	pKd	=	7.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	498	8	0	5	4.7	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2Cc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL462159	176359	0	None	630	2	Rat	7.5	pKd	=	7.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	498	8	0	5	4.7	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2Cc2ccccc21	10.1016/j.bmcl.2009.01.072
	44441917	93818	0	None	1348	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	489	4	0	7	2.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4C#N)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250305	93818	0	None	1348	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	489	4	0	7	2.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4C#N)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564949	12417	0	None	-	1	Rat	8.5	pKd	=	8.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)cc2F)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186651	12417	0	None	-	1	Rat	8.5	pKd	=	8.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)cc2F)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL473762	12417	0	None	-	1	Rat	8.5	pKd	=	8.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)cc2F)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441893	93746	0	None	6456	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	437	3	0	4	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(F)c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL249723	93746	0	None	6456	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	437	3	0	4	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(F)c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441894	154360	0	None	7762	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	437	3	0	4	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(F)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400907	154360	0	None	7762	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	437	3	0	4	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(F)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441870	168554	0	None	2884	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	445	3	0	6	2.3	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C#N)cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL440233	168554	0	None	2884	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	445	3	0	6	2.3	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C#N)cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441674	154068	0	None	3890	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	498	4	0	6	3.6	COc1ccc(Cl)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL399267	154068	0	None	3890	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	498	4	0	6	3.6	COc1ccc(Cl)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44564909	12411	0	None	-	1	Rat	8.4	pKd	=	8.4	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	457	7	0	3	5.0	CN(CCC(=O)N1CCN(c2cccc(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186614	12411	0	None	-	1	Rat	8.4	pKd	=	8.4	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	457	7	0	3	5.0	CN(CCC(=O)N1CCN(c2cccc(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL472752	12411	0	None	-	1	Rat	8.4	pKd	=	8.4	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	457	7	0	3	5.0	CN(CCC(=O)N1CCN(c2cccc(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441883	93943	0	None	999	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	461	3	0	7	2.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5nonc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250921	93943	0	None	999	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	461	3	0	7	2.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5nonc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44447062	94132	0	None	812	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	459	3	1	5	3.4	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252029	94132	0	None	812	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	459	3	1	5	3.4	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441926	93941	0	None	77	2	Rat	7.5	pKd	=	7.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	417	3	0	4	3.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CC=C(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250914	93941	0	None	77	2	Rat	7.5	pKd	=	7.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	417	3	0	4	3.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CC=C(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44447025	154396	0	None	25	2	Rat	6.5	pKd	=	6.5	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	3	1	6	2.3	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(S(C)(=O)=O)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL401108	154396	0	None	25	2	Rat	6.5	pKd	=	6.5	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	3	1	6	2.3	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(S(C)(=O)=O)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44564952	12395	0	None	-	1	Rat	7.5	pKd	=	7.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	5.9	CN(CCC(=O)N1CCN(c2ccc(C(F)(F)F)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186578	12395	0	None	-	1	Rat	7.5	pKd	=	7.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	5.9	CN(CCC(=O)N1CCN(c2ccc(C(F)(F)F)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL470500	12395	0	None	-	1	Rat	7.5	pKd	=	7.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	5.9	CN(CCC(=O)N1CCN(c2ccc(C(F)(F)F)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	155544425	172800	0	None	-14125	5	Human	6.5	pKd	=	6.5	Binding	Displacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 minsDisplacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 mins	ChEMBL	1785	27	15	26	3.3	COc1cc2cc(c1Cl)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCSSC[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc3ccccc3)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O)[C@@]1(C)O[C@H]1[C@H](C)[C@@H]1C[C@@](O)(NC(=O)O1)[C@H](OC)/C=C/C=C(\C)C2	10.1021/acs.jmedchem.8b02036
	CHEMBL4527856	172800	0	None	-14125	5	Human	6.5	pKd	=	6.5	Binding	Displacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 minsDisplacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 mins	ChEMBL	1785	27	15	26	3.3	COc1cc2cc(c1Cl)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCSSC[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc3ccccc3)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O)[C@@]1(C)O[C@H]1[C@H](C)[C@@H]1C[C@@](O)(NC(=O)O1)[C@H](OC)/C=C/C=C(\C)C2	10.1021/acs.jmedchem.8b02036
	CHEMBL407571	210912	0	None	-309	4	Human	6.5	pKd	=	6.5	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		CN[C@H](Cc1ccccc1)C(=O)N[C@@H]1CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm000361p
	44564784	176357	0	None	43	2	Rat	6.5	pKd	=	6.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	485	8	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCn1c2ccccc2c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL462157	176357	0	None	43	2	Rat	6.5	pKd	=	6.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	485	8	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCn1c2ccccc2c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441679	93645	0	None	83	2	Rat	7.5	pKd	=	7.5	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	520	4	0	9	2.7	COc1ccc(C(C)=O)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL249111	93645	0	None	83	2	Rat	7.5	pKd	=	7.5	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	520	4	0	9	2.7	COc1ccc(C(C)=O)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44441882	93942	0	None	19	2	Rat	6.5	pKd	=	6.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	472	3	0	7	2.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cc5nccnc5cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250920	93942	0	None	19	2	Rat	6.5	pKd	=	6.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	472	3	0	7	2.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cc5nccnc5cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL2370167	208051	0	None	-1621	5	Human	5.5	pKd	=	5.5	Binding	In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCNC(=O)[C@@H](N)Cc2ccccc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)CN([C@H](C)c2ccccc2)C(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm970393l
	CHEMBL405421	210803	0	None	-363	4	Human	6.4	pKd	=	6.4	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](N(C)C(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	46880590	5450	0	None	2	2	Human	7.4	pKd	=	7.4	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	549	6	0	5	5.2	Cc1cn2cc(C[C@H](C)CN3C[C@@H](C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)[C@H]4CCCC[C@H]4C3)ccc2n1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076627	5450	0	None	2	2	Human	7.4	pKd	=	7.4	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	549	6	0	5	5.2	Cc1cn2cc(C[C@H](C)CN3C[C@@H](C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)[C@H]4CCCC[C@H]4C3)ccc2n1	10.1016/j.bmcl.2010.01.063
	46880582	5459	0	None	-295	2	Human	6.4	pKd	=	6.4	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(CC(C)CN2C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)[C@H]3CCCC[C@H]3C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076659	5459	0	None	-295	2	Human	6.4	pKd	=	6.4	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(CC(C)CN2C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)[C@H]3CCCC[C@H]3C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	44447058	154401	0	None	1412	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	482	2	1	3	4.8	CN1C[C@H](C(=O)N2CCN(c3ccc(Cl)cc3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL401131	154401	0	None	1412	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	482	2	1	3	4.8	CN1C[C@H](C(=O)N2CCN(c3ccc(Cl)cc3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447011	94344	0	None	3715	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	2	1	4	3.6	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL253438	94344	0	None	3715	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	2	1	4	3.6	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44565116	12513	0	None	-	1	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	483	7	0	5	4.6	CN(CCC(=O)N1CCN(c2ccc3c(c2)OCO3)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187145	12513	0	None	-	1	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	483	7	0	5	4.6	CN(CCC(=O)N1CCN(c2ccc3c(c2)OCO3)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL491498	12513	0	None	-	1	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	483	7	0	5	4.6	CN(CCC(=O)N1CCN(c2ccc3c(c2)OCO3)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44565012	12515	0	None	-	1	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	464	7	0	4	4.7	CN(CCC(=O)N1CCN(c2ccccc2C#N)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187147	12515	0	None	-	1	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	464	7	0	4	4.7	CN(CCC(=O)N1CCN(c2ccccc2C#N)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL491508	12515	0	None	-	1	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	464	7	0	4	4.7	CN(CCC(=O)N1CCN(c2ccccc2C#N)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441675	93568	0	None	1995	2	Rat	8.3	pKd	=	8.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	542	4	0	6	3.8	COc1ccc(Br)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL248716	93568	0	None	1995	2	Rat	8.3	pKd	=	8.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	542	4	0	6	3.8	COc1ccc(Br)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44564816	188912	0	None	194	2	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	512	9	0	5	5.5	CC(C)N(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL514027	188912	0	None	194	2	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	512	9	0	5	5.5	CC(C)N(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441664	94082	0	None	3235	2	Rat	8.3	pKd	=	8.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	550	4	0	8	4.3	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OC(=O)OC(C)(C)C)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL251751	94082	0	None	3235	2	Rat	8.3	pKd	=	8.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	550	4	0	8	4.3	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OC(=O)OC(C)(C)C)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44447077	94166	0	None	4	7	Rat	6.4	pKd	=	6.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	523	2	1	5	2.9	CN1C[C@@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252231	94166	0	None	4	7	Rat	6.4	pKd	=	6.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	523	2	1	5	2.9	CN1C[C@@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	46880583	5447	0	None	-194	2	Human	6.4	pKd	=	6.4	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(C[C@@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)[C@H]3CCCC[C@H]3C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076620	5447	0	None	-194	2	Human	6.4	pKd	=	6.4	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(C[C@@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)[C@H]3CCCC[C@H]3C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	44564857	178350	0	None	1	4	Rat	7.3	pKd	=	7.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	524	10	0	5	5.5	O=C(CCN(CCC1c2ccccc2-c2ccccc21)CC1CC1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1	10.1016/j.bmcl.2009.01.072
	CHEMBL470331	178350	0	None	1	4	Rat	7.3	pKd	=	7.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	524	10	0	5	5.5	O=C(CCN(CCC1c2ccccc2-c2ccccc21)CC1CC1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1	10.1016/j.bmcl.2009.01.072
	46865535	5449	0	None	-134	7	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	550	6	0	5	5.7	Cc1nc2cc(C[C@H](C)CN3C[C@@H](C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)[C@H]4CCCC[C@H]4C3)ccc2o1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076622	5449	0	None	-134	7	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	550	6	0	5	5.7	Cc1nc2cc(C[C@H](C)CN3C[C@@H](C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)[C@H]4CCCC[C@H]4C3)ccc2o1	10.1016/j.bmcl.2010.01.063
	44441931	154272	0	None	19	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	433	4	0	4	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(Cc4ccccc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400386	154272	0	None	19	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	433	4	0	4	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(Cc4ccccc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL421362	211516	0	None	-1258	5	Human	5.3	pKd	=	5.3	Binding	In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm970393l
	44441869	154319	0	None	58	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	421	3	0	6	1.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ncccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400677	154319	0	None	58	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	421	3	0	6	1.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ncccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	46880575	5452	0	None	-3	2	Human	6.3	pKd	=	6.3	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.7	CC(Cc1ccc2c(c1)OCO2)CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2CCCC[C@@H]21	10.1016/j.bmcl.2010.01.063
	CHEMBL1076652	5452	0	None	-3	2	Human	6.3	pKd	=	6.3	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.7	CC(Cc1ccc2c(c1)OCO2)CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2CCCC[C@@H]21	10.1016/j.bmcl.2010.01.063
	44441927	93976	0	None	4	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	418	3	0	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CC=C(c4ncccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251110	93976	0	None	4	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	418	3	0	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CC=C(c4ncccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441928	93977	0	None	4	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	474	3	1	5	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCC(n4c(=O)[nH]c5ccccc54)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251111	93977	0	None	4	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	474	3	1	5	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCC(n4c(=O)[nH]c5ccccc54)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	10162564	12418	0	None	-9	8	Human	8.3	pKd	=	8.3	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186652	12418	0	None	-9	8	Human	8.3	pKd	=	8.3	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL473763	12418	0	None	-9	8	Human	8.3	pKd	=	8.3	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44447060	193153	0	None	363	2	Rat	8.3	pKd	=	8.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	526	2	1	3	4.9	CN1C[C@H](C(=O)N2CCN(c3ccc(Cl)cc3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL539415	193153	0	None	363	2	Rat	8.3	pKd	=	8.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	526	2	1	3	4.9	CN1C[C@H](C(=O)N2CCN(c3ccc(Cl)cc3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441881	153744	0	None	2454	2	Rat	8.2	pKd	=	8.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	472	3	0	7	2.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nccnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL398656	153744	0	None	2454	2	Rat	8.2	pKd	=	8.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	472	3	0	7	2.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nccnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44447078	94167	0	None	-2	7	Human	6.3	pKd	=	6.3	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	534	2	1	6	3.8	CN1C[C@@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252232	94167	0	None	-2	7	Human	6.3	pKd	=	6.3	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	534	2	1	6	3.8	CN1C[C@@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	44441868	154290	0	None	478	2	Rat	7.3	pKd	=	7.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	421	3	0	6	1.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccnn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400481	154290	0	None	478	2	Rat	7.3	pKd	=	7.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	421	3	0	6	1.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccnn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	46880577	5454	0	None	-3	2	Human	6.3	pKd	=	6.3	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.7	CC(Cc1ccc2c(c1)OCO2)CN1C[C@@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2CCCC[C@H]21	10.1016/j.bmcl.2010.01.063
	CHEMBL1076654	5454	0	None	-3	2	Human	6.3	pKd	=	6.3	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.7	CC(Cc1ccc2c(c1)OCO2)CN1C[C@@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2CCCC[C@H]21	10.1016/j.bmcl.2010.01.063
	44441872	93822	0	None	18	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	568	5	0	8	2.7	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ncccc4OS(=O)(=O)C(F)(F)F)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250314	93822	0	None	18	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	568	5	0	8	2.7	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ncccc4OS(=O)(=O)C(F)(F)F)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	9871544	14086	1	None	-120	11	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076624	14086	1	None	-120	11	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1198948	14086	1	None	-120	11	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	44441914	153357	0	None	15	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	498	4	1	6	1.7	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(S(N)(=O)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL398319	153357	0	None	15	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	498	4	1	6	1.7	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(S(N)(=O)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441668	94083	0	None	1202	2	Rat	8.2	pKd	=	8.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	476	4	0	6	3.2	CC(=O)c1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL251752	94083	0	None	1202	2	Rat	8.2	pKd	=	8.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	476	4	0	6	3.2	CC(=O)c1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44565066	12510	0	None	-	1	Rat	8.2	pKd	=	8.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	471	7	0	6	3.0	CN(CCC(=O)N1CCN(c2ccc(=O)n(C)n2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187128	12510	0	None	-	1	Rat	8.2	pKd	=	8.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	471	7	0	6	3.0	CN(CCC(=O)N1CCN(c2ccc(=O)n(C)n2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL491145	12510	0	None	-	1	Rat	8.2	pKd	=	8.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	471	7	0	6	3.0	CN(CCC(=O)N1CCN(c2ccc(=O)n(C)n2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44565008	12543	0	None	-	1	Rat	7.2	pKd	=	7.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	5.9	CN(CCC(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187261	12543	0	None	-	1	Rat	7.2	pKd	=	7.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	5.9	CN(CCC(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL495264	12543	0	None	-	1	Rat	7.2	pKd	=	7.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	5.9	CN(CCC(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL413830	211331	0	None	-23	5	Human	6.2	pKd	=	6.2	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)N(C)[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm000361p
	46880579	5456	0	None	-5	2	Human	5.2	pKd	=	5.2	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.6	CC(Cc1ccc2c(c1)OCO2)CN1C[C@H]2CCCC[C@H]2[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076656	5456	0	None	-5	2	Human	5.2	pKd	=	5.2	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.6	CC(Cc1ccc2c(c1)OCO2)CN1C[C@H]2CCCC[C@H]2[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C1	10.1016/j.bmcl.2010.01.063
	CHEMBL409019	210985	0	None	-21	5	Human	6.2	pKd	=	6.2	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1C)C(N)=O	10.1021/jm000361p
	44441913	93796	0	None	13	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	497	4	0	6	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(S(C)(=O)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250098	93796	0	None	13	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	497	4	0	6	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(S(C)(=O)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441905	93901	0	None	38	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	435	3	1	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250704	93901	0	None	38	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	435	3	1	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL386676	210629	0	None	-16	4	Human	6.2	pKd	=	6.2	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N(C)[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	44441878	93906	0	None	7	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	484	3	0	5	3.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cc(C)nc5ccccc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250723	93906	0	None	7	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	484	3	0	5	3.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cc(C)nc5ccccc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564856	179082	0	None	575	2	Rat	8.2	pKd	=	8.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	510	10	0	5	5.3	C=CCN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL474345	179082	0	None	575	2	Rat	8.2	pKd	=	8.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	510	10	0	5	5.3	C=CCN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441875	168555	0	None	1513	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	450	3	0	6	1.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(=O)n4C)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL440235	168555	0	None	1513	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	450	3	0	6	1.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(=O)n4C)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564783	176341	0	None	-10	4	Human	8.1	pKd	=	8.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	484	8	0	5	4.8	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2010.01.063
	CHEMBL461988	176341	0	None	-10	4	Human	8.1	pKd	=	8.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	484	8	0	5	4.8	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2010.01.063
	44441874	153742	0	None	1548	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	436	3	1	5	1.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(=O)[nH]4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL398655	153742	0	None	1548	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	436	3	1	5	1.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(=O)[nH]4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441676	93569	0	None	1258	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	510	5	0	7	3.7	COc1ccc(SC)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL248717	93569	0	None	1258	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	510	5	0	7	3.7	COc1ccc(SC)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44441930	94011	0	None	87	2	Rat	7.2	pKd	=	7.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	429	2	1	3	3.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCc4c([nH]c5ccccc45)C3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251300	94011	0	None	87	2	Rat	7.2	pKd	=	7.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	429	2	1	3	3.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCc4c([nH]c5ccccc45)C3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL2370168	208052	0	None	-1548	5	Human	5.2	pKd	=	5.2	Binding	In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCNC(=O)[C@@H](N)Cc2ccccc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)CN(Cc2ccccc2)C(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm970393l
	46880588	14087	0	None	1	7	Human	6.1	pKd	=	6.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@@H](C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076625	14087	0	None	1	7	Human	6.1	pKd	=	6.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@@H](C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1198974	14087	0	None	1	7	Human	6.1	pKd	=	6.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@@H](C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL408752	210973	0	None	-5011	4	Human	6.1	pKd	=	6.1	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	44564857	178350	0	None	-1	4	Human	7.1	pKd	=	7.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	524	10	0	5	5.5	O=C(CCN(CCC1c2ccccc2-c2ccccc21)CC1CC1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1	10.1016/j.bmcl.2010.01.063
	CHEMBL470331	178350	0	None	-1	4	Human	7.1	pKd	=	7.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	524	10	0	5	5.5	O=C(CCN(CCC1c2ccccc2-c2ccccc21)CC1CC1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1	10.1016/j.bmcl.2010.01.063
	44564785	176358	0	None	112	2	Rat	7.1	pKd	=	7.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	446	8	0	5	4.0	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCc1cccc2ccccc12	10.1016/j.bmcl.2009.01.072
	CHEMBL462158	176358	0	None	112	2	Rat	7.1	pKd	=	7.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	446	8	0	5	4.0	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCc1cccc2ccccc12	10.1016/j.bmcl.2009.01.072
	44441898	93776	0	None	1230	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	444	3	0	5	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C#N)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL249932	93776	0	None	1230	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	444	3	0	5	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C#N)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441877	93856	0	None	602	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	494	3	0	5	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5ccc(C#N)cc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250522	93856	0	None	602	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	494	3	0	5	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5ccc(C#N)cc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441924	93940	0	None	30	2	Rat	7.1	pKd	=	7.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	450	3	0	3	4.7	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CC=C(c4ccc(Cl)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250912	93940	0	None	30	2	Rat	7.1	pKd	=	7.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	450	3	0	3	4.7	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CC=C(c4ccc(Cl)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL413373	211304	0	None	-269	4	Human	6.1	pKd	=	6.1	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		CN[C@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm000361p
	46880588	14087	0	None	-1	7	Rat	6.1	pKd	=	6.1	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@@H](C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076625	14087	0	None	-1	7	Rat	6.1	pKd	=	6.1	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@@H](C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1198974	14087	0	None	-1	7	Rat	6.1	pKd	=	6.1	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@@H](C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)C2)cn1	10.1016/j.bmcl.2010.01.063
	44441912	14532	0	None	-	1	Rat	4.1	pKd	=	4.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	463	4	1	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(=O)O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL1206217	14532	0	None	-	1	Rat	4.1	pKd	=	4.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	463	4	1	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(=O)O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL249894	14532	0	None	-	1	Rat	4.1	pKd	=	4.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	463	4	1	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(=O)O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL405561	210809	0	None	-316	4	Human	6.1	pKd	=	6.1	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](N(C)C(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	CHEMBL412466	211235	0	None	-467	4	Human	6.1	pKd	=	6.1	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N(C)[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	44441876	93855	0	None	63	2	Rat	7.1	pKd	=	7.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	469	3	0	4	4.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5ccccc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250521	93855	0	None	63	2	Rat	7.1	pKd	=	7.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	469	3	0	4	4.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5ccccc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441887	93980	0	None	239	2	Rat	7.1	pKd	=	7.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	460	3	0	7	2.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nccn5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251121	93980	0	None	239	2	Rat	7.1	pKd	=	7.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	460	3	0	7	2.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nccn5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	46880578	5455	0	None	-83	2	Human	6.0	pKd	=	6.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.6	CC(Cc1ccc2c(c1)OCO2)CN1C[C@H]2CCCC[C@H]2[C@@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076655	5455	0	None	-83	2	Human	6.0	pKd	=	6.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.6	CC(Cc1ccc2c(c1)OCO2)CN1C[C@H]2CCCC[C@H]2[C@@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C1	10.1016/j.bmcl.2010.01.063
	46880852	5474	0	None	-107	2	Human	6.0	pKd	=	6.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	539	6	0	5	5.0	C[C@@H](Cc1ccc2c(c1)OCO2)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076717	5474	0	None	-107	2	Human	6.0	pKd	=	6.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	539	6	0	5	5.0	C[C@@H](Cc1ccc2c(c1)OCO2)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	46880854	5476	0	None	-263	2	Human	5.0	pKd	=	5.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	536	6	0	6	4.3	C[C@@H](Cc1ccc2ncnn2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076719	5476	0	None	-263	2	Human	5.0	pKd	=	5.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	536	6	0	6	4.3	C[C@@H](Cc1ccc2ncnn2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	46880584	5448	0	None	-758	2	Human	6.0	pKd	=	6.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)[C@H]3CCCC[C@H]3C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076621	5448	0	None	-758	2	Human	6.0	pKd	=	6.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)[C@H]3CCCC[C@H]3C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL411017	211101	0	None	-67	4	Human	6.0	pKd	=	6.0	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N(C)[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	CHEMBL3349516	209661	0	None	-1	4	Human	9.8	pKi	=	9.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL3349522	209666	0	None	-1	4	Human	9.7	pKi	=	9.7	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL3349521	209665	0	None	-1	4	Human	9.6	pKi	=	9.6	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	16129706	207277	36	None	-6	5	Human	9.5	pKi	=	9.5	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm0108449
	CHEMBL1823872	207277	36	None	-6	5	Human	9.5	pKi	=	9.5	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm0108449
	CHEMBL3098601	209262	0	None	-1	5	Human	9.5	pKi	=	9.5	Binding	Displacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cellsDisplacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1C/C=C\C[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.bmcl.2013.11.065
	CHEMBL1823873	207278	7	None	1	4	Human	9.5	pKi	=	9.5	Binding	Displacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cellsDisplacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.bmcl.2013.11.065
	16129706	207277	36	None	-6	5	Human	9.4	pKi	=	9.4	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/s0960-894x(01)00107-x
	CHEMBL1823872	207277	36	None	-6	5	Human	9.4	pKi	=	9.4	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/s0960-894x(01)00107-x
	16129706	207277	36	None	-6	5	Human	9.4	pKi	=	9.4	Binding	Binding affinity towards Somatostatin receptor type 1 (hsst1)Binding affinity towards Somatostatin receptor type 1 (hsst1)	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm020424z
	CHEMBL1823872	207277	36	None	-6	5	Human	9.4	pKi	=	9.4	Binding	Binding affinity towards Somatostatin receptor type 1 (hsst1)Binding affinity towards Somatostatin receptor type 1 (hsst1)	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm020424z
	CHEMBL408362	210953	0	None	-9	5	Human	9.4	pKi	=	9.4	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm980194h
	16129706	207277	36	None	-6	5	Human	9.4	pKi	=	9.4	Binding	Displacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cellsDisplacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.bmcl.2013.11.065
	CHEMBL1823872	207277	36	None	-6	5	Human	9.4	pKi	=	9.4	Binding	Displacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cellsDisplacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.bmcl.2013.11.065
	CHEMBL3349517	209662	0	None	-1	4	Human	9.3	pKi	=	9.3	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	16129706	207277	36	None	-6	5	Human	9.2	pKi	=	9.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL1823872	207277	36	None	-6	5	Human	9.2	pKi	=	9.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL3349518	209663	0	None	10	4	Human	9.2	pKi	=	9.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL3349513	209658	0	None	-1	4	Human	9.1	pKi	=	9.1	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC1=O	10.1021/jm021093t
	CHEMBL3349605	209678	0	None	-6	4	Human	8.8	pKi	=	8.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H]2C[C@@H](OC(=O)NCCN)CN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC1=O	10.1021/jm021093t
	CHEMBL3349606	209679	0	None	-15	4	Human	8.8	pKi	=	8.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		CN(C)CCNC(=O)O[C@@H]1C[C@H]2C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc3ccc(OCc4ccccc4)cc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N2C1	10.1021/jm021093t
	44308969	202651	0	None	1096	5	Human	8.8	pKi	=	8.8	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	539	7	4	3	4.7	NC[C@@H]1CCC[C@H](CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(C=Cc4ccccc43)CC2)C1	10.1021/jm980194h
	CHEMBL71723	202651	0	None	1096	5	Human	8.8	pKi	=	8.8	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	539	7	4	3	4.7	NC[C@@H]1CCC[C@H](CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(C=Cc4ccccc43)CC2)C1	10.1021/jm980194h
	CHEMBL442494	212155	0	None	-6	5	Human	8.7	pKi	=	8.7	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm0005048
	CHEMBL3349603	209676	0	None	-15	5	Human	8.0	pKi	=	8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		NCCCCCNC(=O)O[C@@H]1C[C@H]2C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc3ccc(OCc4ccccc4)cc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N2C1	10.1021/jm021093t
	91809310	125251	0	None	-43	4	Human	8.0	pKi	=	8.0	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1618	27	19	17	3.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647709	125251	0	None	-43	4	Human	8.0	pKi	=	8.0	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1618	27	19	17	3.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	91809283	125226	0	None	-1258	6	Human	7.0	pKi	=	7	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1456	23	17	16	2.8	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647684	125226	0	None	-1258	6	Human	7.0	pKi	=	7	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1456	23	17	16	2.8	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL2311098	207750	0	None	-83	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369733	207906	0	None	-5	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N(C)[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369734	207907	0	None	-14	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)N(C)C1=O	10.1021/jm0005048
	CHEMBL2369735	207908	0	None	-181	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)N(C)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369750	207913	0	None	-27	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		CN[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@H]1CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC(=O)[C@@H]([C@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC1=O	10.1021/jm0005048
	CHEMBL2369751	207914	0	None	-11	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		CNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H]1CSSC[C@H](N(C)C(=O)[C@@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cccnc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@H]([C@H](C)O)C(=O)N1	10.1021/jm0005048
	CHEMBL2369752	207915	0	None	-19	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)N(C)C(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369754	207917	0	None	-107	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)N(C)C(=O)[C@@H](Cc2c[nH]c3ccccc23)N(C)C(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369755	207918	0	None	-165	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)N(C)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369756	207919	0	None	-5	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)N(C)C(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369757	207920	0	None	-40	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)N(C)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2cccnc2)CSSC[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369758	207921	0	None	-36	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)N(C)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369759	207922	0	None	1	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)C(N)CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369760	207923	0	None	-42	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@@H](N)CCNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369761	207924	0	None	-8	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		CNC(=O)[C@@H](NC(=O)[C@@H]1CSSC[C@@H](N(C)C(=O)C(N)Cc2ccc(Cl)cc2)C(=O)N[C@@H](Cc2cccnc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@H]([C@H](C)O)C(=O)N1)C(c1ccccc1)c1ccccc1	10.1021/jm0005048
	CHEMBL2371893	208392	0	None	-89	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)N(C)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(C(F)(F)F)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL3349515	209660	0	None	-12	4	Human	6.0	pKi	=	6	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL3349525	209668	0	None	-10	4	Human	6.0	pKi	=	6	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	142471769	191179	0	None	-301	2	Human	6.0	pKi	=	6	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	456	10	2	6	4.3	COc1ccc(Cc2nnc(Cc3c[nH]c4ccc(OC)cc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5198142	191179	0	None	-301	2	Human	6.0	pKi	=	6	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	456	10	2	6	4.3	COc1ccc(Cc2nnc(Cc3c[nH]c4ccc(OC)cc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	44387399	168440	0	None	-2	3	Human	6.0	pKi	=	6.0	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL	1055	13	11	14	1.3	CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@H](NN2Cc3ccccc3CC2C(=O)O)CSSC[C@@H](C(=O)NN2Cc3ccccc3CC2C(=O)O)NC1=O	10.1021/jm9806289
	CHEMBL439350	168440	0	None	-2	3	Human	6.0	pKi	=	6.0	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL	1055	13	11	14	1.3	CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@H](NN2Cc3ccccc3CC2C(=O)O)CSSC[C@@H](C(=O)NN2Cc3ccccc3CC2C(=O)O)NC1=O	10.1021/jm9806289
	CHEMBL385746	210607	0	None	-72	4	Human	6.0	pKi	=	6.0	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	142471841	190979	0	None	-363	3	Human	6.0	pKi	=	6.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	5	4.4	COc1ccc2[nH]cc(Cc3nnc(Cc4ccc(F)cc4)n3CCCc3c[nH]cn3)c2c1	10.1039/D1MD00044F
	CHEMBL5195145	190979	0	None	-363	3	Human	6.0	pKi	=	6.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	5	4.4	COc1ccc2[nH]cc(Cc3nnc(Cc4ccc(F)cc4)n3CCCc3c[nH]cn3)c2c1	10.1039/D1MD00044F
	91809284	125227	0	None	-512	6	Human	7.0	pKi	=	7.0	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1896	34	20	20	5.5	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647685	125227	0	None	-512	6	Human	7.0	pKi	=	7.0	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1896	34	20	20	5.5	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL385689	210602	0	None	-15	4	Human	6.0	pKi	=	6.0	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc(F)cc2)C(N)=O)NC1=O	10.1021/jm9806289
	142471716	190886	0	None	-208	3	Human	6.0	pKi	=	6.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	5	4.4	COc1ccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5193686	190886	0	None	-208	3	Human	6.0	pKi	=	6.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	5	4.4	COc1ccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	142471929	190563	0	None	-676	2	Human	5.9	pKi	=	5.9	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	414	8	2	4	4.4	Fc1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5188841	190563	0	None	-676	2	Human	5.9	pKi	=	5.9	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	414	8	2	4	4.4	Fc1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL414116	211353	0	None	-5	4	Human	5.9	pKi	=	5.9	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	90665463	108762	0	None	-4	5	Human	4.9	pKi	=	4.9	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	882	28	3	9	4.5	COC(=O)CCN(Cc1ccccc1)C(=O)CCN(C[C@@H](C)O)C(=O)CCN(CCCCN)C(=O)CCN(CCc1c[nH]c2ccccc12)C(=O)CCN(Cc1ccccc1)C(C)=O	10.1039/C2MD20265D
	CHEMBL3218124	108762	0	None	-4	5	Human	4.9	pKi	=	4.9	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	882	28	3	9	4.5	COC(=O)CCN(Cc1ccccc1)C(=O)CCN(C[C@@H](C)O)C(=O)CCN(CCCCN)C(=O)CCN(CCc1c[nH]c2ccccc12)C(=O)CCN(Cc1ccccc1)C(C)=O	10.1039/C2MD20265D
	168288485	191125	0	None	-2454	4	Human	5.9	pKi	=	5.9	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	430	8	2	4	5.0	Clc1cccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5197201	191125	0	None	-2454	4	Human	5.9	pKi	=	5.9	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	430	8	2	4	5.0	Clc1cccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL3349514	209659	0	None	-6	4	Human	6.9	pKi	=	6.9	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	44397706	66840	0	None	-70	5	Human	6.9	pKi	=	6.9	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	456	9	2	6	5.4	Cc1cccc2c(CCSc3nnc(-c4ccc5ccccc5n4)n3CCCCN)c[nH]c12	10.1016/j.bmcl.2005.05.061
	CHEMBL187768	66840	0	None	-70	5	Human	6.9	pKi	=	6.9	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	456	9	2	6	5.4	Cc1cccc2c(CCSc3nnc(-c4ccc5ccccc5n4)n3CCCCN)c[nH]c12	10.1016/j.bmcl.2005.05.061
	CHEMBL2369749	207912	0	None	-114	5	Human	5.9	pKi	=	5.9	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	10296743	61494	0	None	-	1	Human	5.9	pKi	=	5.9	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	436	7	3	3	5.8	O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)OCc1ccccc1	10.1016/s0960-894x(01)00107-x
	CHEMBL177337	61494	0	None	-	1	Human	5.9	pKi	=	5.9	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	436	7	3	3	5.8	O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)OCc1ccccc1	10.1016/s0960-894x(01)00107-x
	CHEMBL408347	210950	0	None	-117	4	Human	5.9	pKi	=	5.9	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	142471978	191835	0	None	-891	2	Human	5.8	pKi	=	5.8	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	396	8	2	4	4.3	c1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5208396	191835	0	None	-891	2	Human	5.8	pKi	=	5.8	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	396	8	2	4	4.3	c1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	44385652	60058	0	None	-6	5	Human	5.8	pKi	=	5.8	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	405	6	4	2	5.5	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccccc1	10.1016/s0960-894x(01)00107-x
	CHEMBL174872	60058	0	None	-6	5	Human	5.8	pKi	=	5.8	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	405	6	4	2	5.5	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccccc1	10.1016/s0960-894x(01)00107-x
	10210016	60099	0	None	-7	3	Human	5.8	pKi	=	5.8	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	441	6	4	2	5.7	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(F)cc1F	10.1016/s0960-894x(01)00107-x
	CHEMBL175197	60099	0	None	-7	3	Human	5.8	pKi	=	5.8	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	441	6	4	2	5.7	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(F)cc1F	10.1016/s0960-894x(01)00107-x
	2054	3899	11	None	-741	11	Human	6.8	pKi	=	6.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	71306	3899	11	None	-741	11	Human	6.8	pKi	=	6.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	CHEMBL264186	3899	11	None	-741	11	Human	6.8	pKi	=	6.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	CHEMBL3349523	3899	11	None	-741	11	Human	6.8	pKi	=	6.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	DB04894	3899	11	None	-741	11	Human	6.8	pKi	=	6.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	91809287	159699	0	None	-3162	6	Human	6.8	pKi	=	6.8	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1472	23	17	16	1.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCC[S@+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL4110066	159699	0	None	-3162	6	Human	6.8	pKi	=	6.8	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1472	23	17	16	1.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCC[S@+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	90665462	108730	0	None	-5	4	Human	4.8	pKi	=	4.8	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	867	27	3	9	4.1	COC(=O)CCN(Cc1ccccc1)C(=O)CCN(C[C@@H](C)O)C(=O)CCN(CCCCN)C(=O)CN(CCc1c[nH]c2ccccc12)C(=O)CCN(Cc1ccccc1)C(C)=O	10.1039/C2MD20265D
	CHEMBL3217760	108730	0	None	-5	4	Human	4.8	pKi	=	4.8	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	867	27	3	9	4.1	COC(=O)CCN(Cc1ccccc1)C(=O)CCN(C[C@@H](C)O)C(=O)CCN(CCCCN)C(=O)CN(CCc1c[nH]c2ccccc12)C(=O)CCN(Cc1ccccc1)C(C)=O	10.1039/C2MD20265D
	90665460	108760	0	None	-7	5	Human	4.8	pKi	=	4.8	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	793	13	3	7	3.9	C[C@@H](O)CN1CCC(=O)N(Cc2ccccc2)CCC(=O)N(Cc2ccccc2)CCC(=O)N(CCc2c[nH]c3ccccc23)CC(=O)N(CCCCN)CCC1=O	10.1039/C2MD20265D
	CHEMBL3218122	108760	0	None	-7	5	Human	4.8	pKi	=	4.8	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	793	13	3	7	3.9	C[C@@H](O)CN1CCC(=O)N(Cc2ccccc2)CCC(=O)N(Cc2ccccc2)CCC(=O)N(CCc2c[nH]c3ccccc23)CC(=O)N(CCCCN)CCC1=O	10.1039/C2MD20265D
	CHEMBL385745	210606	0	None	-15	4	Human	5.8	pKi	=	5.8	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	142471655	189821	0	None	-562	3	Human	5.8	pKi	=	5.8	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	426	9	2	5	4.3	COc1ccc2[nH]cc(Cc3nnc(Cc4ccccc4)n3CCCc3c[nH]cn3)c2c1	10.1039/D1MD00044F
	CHEMBL5178013	189821	0	None	-562	3	Human	5.8	pKi	=	5.8	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	426	9	2	5	4.3	COc1ccc2[nH]cc(Cc3nnc(Cc4ccccc4)n3CCCc3c[nH]cn3)c2c1	10.1039/D1MD00044F
	10166743	123415	0	None	-21	5	Human	5.8	pKi	=	5.8	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	439	6	4	2	6.1	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(Cl)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL362859	123415	0	None	-21	5	Human	5.8	pKi	=	5.8	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	439	6	4	2	6.1	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(Cl)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL275806	209068	0	None	-1	4	Human	6.8	pKi	=	6.8	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)O)NC1=O	10.1021/jm9806289
	11848679	88800	0	None	-134	6	Human	5.8	pKi	=	5.8	Binding	Displacement of SST14 from human recombinant SST1 receptorDisplacement of SST14 from human recombinant SST1 receptor	ChEMBL	489	9	3	9	2.9	CCOc1cc(CN2CCC(Nc3nc4cc(S(N)(=O)=O)ccc4o3)CC2)cc(OCC)c1N	10.1016/j.bmcl.2009.09.024
	CHEMBL236788	88800	0	None	-134	6	Human	5.8	pKi	=	5.8	Binding	Displacement of SST14 from human recombinant SST1 receptorDisplacement of SST14 from human recombinant SST1 receptor	ChEMBL	489	9	3	9	2.9	CCOc1cc(CN2CCC(Nc3nc4cc(S(N)(=O)=O)ccc4o3)CC2)cc(OCC)c1N	10.1016/j.bmcl.2009.09.024
	44397648	66416	0	None	-44	5	Human	6.8	pKi	=	6.8	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	476	9	2	6	5.7	NCCCCn1c(SCCc2c[nH]c3c(Cl)cccc23)nnc1-c1ccc2ccccc2n1	10.1016/j.bmcl.2005.05.061
	CHEMBL185861	66416	0	None	-44	5	Human	6.8	pKi	=	6.8	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	476	9	2	6	5.7	NCCCCn1c(SCCc2c[nH]c3c(Cl)cccc23)nnc1-c1ccc2ccccc2n1	10.1016/j.bmcl.2005.05.061
	44332931	4542	0	None	-1047	2	Human	5.8	pKi	=	5.8	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	396	3	3	2	6.1	c1ccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCCCC4)N3)n2)cc1	10.1021/jm0108449
	CHEMBL102892	4542	0	None	-1047	2	Human	5.8	pKi	=	5.8	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	396	3	3	2	6.1	c1ccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCCCC4)N3)n2)cc1	10.1021/jm0108449
	CHEMBL1201959	4542	0	None	-1047	2	Human	5.8	pKi	=	5.8	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	396	3	3	2	6.1	c1ccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCCCC4)N3)n2)cc1	10.1021/jm0108449
	142471665	191101	0	None	-602	2	Human	5.7	pKi	=	5.7	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	414	8	2	4	4.4	Fc1ccc2c(Cc3nnc(Cc4ccccc4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL5196971	191101	0	None	-602	2	Human	5.7	pKi	=	5.7	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	414	8	2	4	4.4	Fc1ccc2c(Cc3nnc(Cc4ccccc4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL438281	212005	0	None	1	4	Human	6.7	pKi	=	6.7	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccccc2F)CSSC[C@H](C(=O)N[C@@H](Cc2ccccc2F)C(N)=O)NC1=O	10.1021/jm9806289
	44385757	60992	0	None	-1	4	Human	5.7	pKi	=	5.7	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	461	6	4	2	6.8	CC(C)(C)c1ccc(C(=N)N[C@H](Cc2c[nH]c3ccccc23)c2nc(-c3ccccc3)c[nH]2)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL176730	60992	0	None	-1	4	Human	5.7	pKi	=	5.7	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	461	6	4	2	6.8	CC(C)(C)c1ccc(C(=N)N[C@H](Cc2c[nH]c3ccccc23)c2nc(-c3ccccc3)c[nH]2)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL3349520	209664	0	None	1	4	Human	7.7	pKi	=	7.7	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL407496	210908	0	None	-63	5	Human	5.7	pKi	=	5.7	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(F)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc(F)cc2)C(N)=O)NC1=O	10.1021/jm9806289
	CHEMBL1794035	207184	0	None	-7	5	Human	8.7	pKi	=	8.7	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm0005048
	16129706	207277	36	None	-6	5	Human	8.6	pKi	=	8.6	Binding	Binding affinity towards somatostatin receptor type 1Binding affinity towards somatostatin receptor type 1	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm050376t
	CHEMBL1823872	207277	36	None	-6	5	Human	8.6	pKi	=	8.6	Binding	Binding affinity towards somatostatin receptor type 1Binding affinity towards somatostatin receptor type 1	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm050376t
	10580397	98844	0	None	-4	5	Human	5.7	pKi	=	5.7	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	677	20	3	7	6.9	NCCCCCNC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL282129	98844	0	None	-4	5	Human	5.7	pKi	=	5.7	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	677	20	3	7	6.9	NCCCCCNC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1	10.1021/jm9800346
	142471719	189898	0	None	-204	2	Human	5.7	pKi	=	5.7	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	9	1	5	5.5	Cn1cc(CCc2nnc(Cc3cccc(C(F)(F)F)c3)n2CCCc2c[nH]cn2)c2ccccc21	10.1039/D1MD00044F
	CHEMBL5179321	189898	0	None	-204	2	Human	5.7	pKi	=	5.7	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	9	1	5	5.5	Cn1cc(CCc2nnc(Cc3cccc(C(F)(F)F)c3)n2CCCc2c[nH]cn2)c2ccccc21	10.1039/D1MD00044F
	13690207	114870	0	None	-812	5	Human	6.7	pKi	=	6.7	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1039/C2MD20265D
	CHEMBL3350037	114870	0	None	-812	5	Human	6.7	pKi	=	6.7	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1039/C2MD20265D
	10094509	130151	0	None	-63	5	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	435	7	4	3	5.5	COc1ccc(C(=N)N[C@H](Cc2c[nH]c3ccccc23)c2nc(-c3ccccc3)c[nH]2)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL368334	130151	0	None	-63	5	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	435	7	4	3	5.5	COc1ccc(C(=N)N[C@H](Cc2c[nH]c3ccccc23)c2nc(-c3ccccc3)c[nH]2)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL429166	211751	0	None	-2	4	Human	6.6	pKi	=	6.6	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)(C)C[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	15965425	2167	4	None	-239883	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity towards Somatostatin receptor type 1 (hsst1)Binding affinity towards Somatostatin receptor type 1 (hsst1)	ChEMBL	645	11	5	7	4.3	NCCCC[C@@H](C(=O)OC(C)(C)C)NC(=O)[C@@H]([C@H](c1c[nH]c2c1cccc2)C)NC(=O)N1CCC(CC1)n1c(=O)[nH]c2c1cccc2	10.1021/jm020424z
	2046	2167	4	None	-239883	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity towards Somatostatin receptor type 1 (hsst1)Binding affinity towards Somatostatin receptor type 1 (hsst1)	ChEMBL	645	11	5	7	4.3	NCCCC[C@@H](C(=O)OC(C)(C)C)NC(=O)[C@@H]([C@H](c1c[nH]c2c1cccc2)C)NC(=O)N1CCC(CC1)n1c(=O)[nH]c2c1cccc2	10.1021/jm020424z
	CHEMBL99895	2167	4	None	-239883	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity towards Somatostatin receptor type 1 (hsst1)Binding affinity towards Somatostatin receptor type 1 (hsst1)	ChEMBL	645	11	5	7	4.3	NCCCC[C@@H](C(=O)OC(C)(C)C)NC(=O)[C@@H]([C@H](c1c[nH]c2c1cccc2)C)NC(=O)N1CCC(CC1)n1c(=O)[nH]c2c1cccc2	10.1021/jm020424z
	91809303	125244	0	None	-75	6	Human	7.6	pKi	=	7.6	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1659	28	18	16	3.8	CC(=O)N(CCC(=O)N[C@@H](CN[C@@H]1CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC1=O)Cc1ccc(O)cc1)C[C@@H]1C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1	nan
	CHEMBL3647702	125244	0	None	-75	6	Human	7.6	pKi	=	7.6	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1659	28	18	16	3.8	CC(=O)N(CCC(=O)N[C@@H](CN[C@@H]1CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC1=O)Cc1ccc(O)cc1)C[C@@H]1C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1	nan
	10325243	100016	0	None	-1	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	549	17	1	7	5.3	CO[C@@H]1O[C@H](COCCCCCN)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL29102	100016	0	None	-1	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	549	17	1	7	5.3	CO[C@@H]1O[C@H](COCCCCCN)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	44309052	202240	0	None	-123	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	539	7	4	3	4.7	NC[C@H]1CCC[C@@H](CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(C=Cc4ccccc43)CC2)C1	10.1021/jm980194h
	CHEMBL69303	202240	0	None	-123	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	539	7	4	3	4.7	NC[C@H]1CCC[C@@H](CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(C=Cc4ccccc43)CC2)C1	10.1021/jm980194h
	13690207	114870	0	None	-812	5	Human	6.6	pKi	=	6.6	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1021/jm021093t
	CHEMBL3350037	114870	0	None	-812	5	Human	6.6	pKi	=	6.6	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1021/jm021093t
	44385504	60708	0	None	-6	5	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	489	7	4	3	6.4	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(OC(F)(F)F)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL176313	60708	0	None	-6	5	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	489	7	4	3	6.4	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(OC(F)(F)F)cc1	10.1016/s0960-894x(01)00107-x
	142471684	190846	0	None	-1174	2	Human	5.6	pKi	=	5.6	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	426	9	2	5	4.3	COc1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5193172	190846	0	None	-1174	2	Human	5.6	pKi	=	5.6	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	426	9	2	5	4.3	COc1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	91809306	125247	0	None	-190	4	Human	7.6	pKi	=	7.6	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1738	28	16	17	6.7	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N(CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647705	125247	0	None	-190	4	Human	7.6	pKi	=	7.6	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1738	28	16	17	6.7	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N(CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	10411795	130084	0	None	-15	3	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	457	6	4	2	5.9	O=C(Nc1ccc(F)cc1F)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	CHEMBL368176	130084	0	None	-15	3	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	457	6	4	2	5.9	O=C(Nc1ccc(F)cc1F)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	142471848	190663	0	None	-263	4	Human	6.6	pKi	=	6.6	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	8	2	4	5.2	Fc1ccc2c(Cc3nnc(Cc4cccc(Br)c4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL5190457	190663	0	None	-263	4	Human	6.6	pKi	=	6.6	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	8	2	4	5.2	Fc1ccc2c(Cc3nnc(Cc4cccc(Br)c4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	44385712	60010	0	None	-4	4	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	343	5	4	2	4.4	CC(=N)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	CHEMBL174490	60010	0	None	-4	4	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	343	5	4	2	4.4	CC(=N)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	91809320	125844	0	None	-50	3	Human	7.5	pKi	=	7.5	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1897	34	19	18	6.5	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL3650456	125844	0	None	-50	3	Human	7.5	pKi	=	7.5	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1897	34	19	18	6.5	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	44377555	57212	0	None	-4	5	Human	5.5	pKi	=	5.5	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	384	5	1	5	5.2	NCCCc1nc(-c2csc3ccccc23)cn2cc(-c3ccccc3)nc12	10.1016/s0960-894x(01)00051-8
	CHEMBL166247	57212	0	None	-4	5	Human	5.5	pKi	=	5.5	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	384	5	1	5	5.2	NCCCc1nc(-c2csc3ccccc23)cn2cc(-c3ccccc3)nc12	10.1016/s0960-894x(01)00051-8
	CHEMBL3349601	209674	0	None	-5	4	Human	8.4	pKi	=	8.4	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H]2C[C@@H](OC(=O)NCCN)CN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC1=O	10.1021/jm021093t
	CHEMBL3349602	209675	0	None	-10	5	Human	8.4	pKi	=	8.4	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2C[C@@H](OC(=O)NCCN)CN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC1=O	10.1021/jm021093t
	10009650	99321	0	None	-3	4	Human	6.5	pKi	=	6.5	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	668	20	3	8	6.1	NCCCCCOC[C@@H]1O[C@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2c[nH]cn2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL285333	99321	0	None	-3	4	Human	6.5	pKi	=	6.5	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	668	20	3	8	6.1	NCCCCCOC[C@@H]1O[C@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2c[nH]cn2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	13690207	114870	0	None	-812	5	Human	6.5	pKi	=	6.5	Binding	Displacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cellsDisplacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cells	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1016/j.bmcl.2013.11.065
	CHEMBL3350037	114870	0	None	-812	5	Human	6.5	pKi	=	6.5	Binding	Displacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cellsDisplacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cells	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1016/j.bmcl.2013.11.065
	142471737	189700	0	None	-77	3	Human	5.5	pKi	=	5.5	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	9	1	5	5.8	Cn1cc(CCc2nnc(Cc3ccc(Cl)c(Cl)c3)n2CCCc2c[nH]cn2)c2ccccc21	10.1039/D1MD00044F
	CHEMBL5176020	189700	0	None	-77	3	Human	5.5	pKi	=	5.5	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	9	1	5	5.8	Cn1cc(CCc2nnc(Cc3ccc(Cl)c(Cl)c3)n2CCCc2c[nH]cn2)c2ccccc21	10.1039/D1MD00044F
	91809277	125220	0	None	-107	6	Human	7.5	pKi	=	7.5	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1457	23	16	14	3.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL3647678	125220	0	None	-107	6	Human	7.5	pKi	=	7.5	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1457	23	16	14	3.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	71461645	78479	0	None	-4	4	Human	5.5	pKi	=	5.5	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	367	5	2	4	4.4	NCCCc1nc(-c2c[nH]c3ccccc23)cn2cc(-c3ccccc3)nc12	10.1016/s0960-894x(01)00051-8
	CHEMBL2112935	78479	0	None	-4	4	Human	5.5	pKi	=	5.5	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	367	5	2	4	4.4	NCCCc1nc(-c2c[nH]c3ccccc23)cn2cc(-c3ccccc3)nc12	10.1016/s0960-894x(01)00051-8
	CHEMBL438726	212031	0	None	2	4	Human	7.5	pKi	=	7.5	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(F)c(F)c(F)c(F)c2F)CSSC[C@H](C(=O)N[C@@H](Cc2c(F)c(F)c(F)c(F)c2F)C(N)=O)NC1=O	10.1021/jm9806289
	10248767	56881	0	None	-7	4	Human	5.5	pKi	=	5.5	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	373	6	1	6	3.9	NCCCc1nc(-c2cccc([N+](=O)[O-])c2)cn2cc(-c3ccccc3)nc12	10.1016/s0960-894x(01)00051-8
	CHEMBL164964	56881	0	None	-7	4	Human	5.5	pKi	=	5.5	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	373	6	1	6	3.9	NCCCc1nc(-c2cccc([N+](=O)[O-])c2)cn2cc(-c3ccccc3)nc12	10.1016/s0960-894x(01)00051-8
	44386389	129548	0	None	-6	5	Human	5.5	pKi	=	5.5	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	473	6	4	2	6.5	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(C(F)(F)F)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL367699	129548	0	None	-6	5	Human	5.5	pKi	=	5.5	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	473	6	4	2	6.5	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(C(F)(F)F)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL414386	211371	0	None	-4	4	Human	6.5	pKi	=	6.5	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	142471801	191691	0	None	-199	4	Human	6.4	pKi	=	6.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	494	9	2	5	5.3	COc1ccc2[nH]cc(Cc3nnc(Cc4cccc(C(F)(F)F)c4)n3CCCc3c[nH]cn3)c2c1	10.1039/D1MD00044F
	CHEMBL5206148	191691	0	None	-199	4	Human	6.4	pKi	=	6.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	494	9	2	5	5.3	COc1ccc2[nH]cc(Cc3nnc(Cc4cccc(C(F)(F)F)c4)n3CCCc3c[nH]cn3)c2c1	10.1039/D1MD00044F
	142471923	191304	0	None	-512	2	Human	5.4	pKi	=	5.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	488	10	2	6	3.9	CS(=O)(=O)c1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5200112	191304	0	None	-512	2	Human	5.4	pKi	=	5.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	488	10	2	6	3.9	CS(=O)(=O)c1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL406491	210854	0	None	4	4	Human	7.4	pKi	=	7.4	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccccc2F)CSSC[C@@H](C(=O)N[C@@H](Cc2ccccc2F)C(N)=O)NC1=O	10.1021/jm9806289
	2070	689	3	None	-5888	4	Human	5.4	pKi	=	5.4	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	426	8	3	2	7.0	CCCCC1(CCCC)N[C@H](Cc2c1[nH]c1c2cccc1)c1ncc([nH]1)c1ccccc1	10.1021/jm0108449
	9802572	689	3	None	-5888	4	Human	5.4	pKi	=	5.4	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	426	8	3	2	7.0	CCCCC1(CCCC)N[C@H](Cc2c1[nH]c1c2cccc1)c1ncc([nH]1)c1ccccc1	10.1021/jm0108449
	CHEMBL2069499	689	3	None	-5888	4	Human	5.4	pKi	=	5.4	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	426	8	3	2	7.0	CCCCC1(CCCC)N[C@H](Cc2c1[nH]c1c2cccc1)c1ncc([nH]1)c1ccccc1	10.1021/jm0108449
	CHEMBL437448	211961	0	None	-23	5	Human	6.4	pKi	=	6.4	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Br)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc(Br)cc2)C(N)=O)NC1=O	10.1021/jm9806289
	91809275	125218	0	None	-316	6	Human	7.4	pKi	=	7.4	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1603	27	18	17	3.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647676	125218	0	None	-316	6	Human	7.4	pKi	=	7.4	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1603	27	18	17	3.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL2369753	207916	0	None	-4	5	Human	6.4	pKi	=	6.4	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@@H]1C(=O)N[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)CSSC[C@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)C(=O)N[C@@H](Cc2cccnc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N1C	10.1021/jm0005048
	9852911	98911	0	None	-26	6	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	678	20	2	7	7.4	NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL282618	98911	0	None	-26	6	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	678	20	2	7	7.4	NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1	10.1021/jm9800346
	10770814	100312	0	None	-2	5	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	678	20	2	7	7.4	NCCCCCOC[C@@H]1O[C@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL29311	100312	0	None	-2	5	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	678	20	2	7	7.4	NCCCCCOC[C@@H]1O[C@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	44377591	55329	0	None	-1	4	Human	5.4	pKi	=	5.4	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	536	9	3	6	5.6	CC(C)(C(=O)NCCc1c[nH]c2ccccc12)c1cn2cc(-c3csc4ccccc34)nc(CCCN)c2n1	10.1016/s0960-894x(01)00051-8
	CHEMBL162140	55329	0	None	-1	4	Human	5.4	pKi	=	5.4	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	536	9	3	6	5.6	CC(C)(C(=O)NCCc1c[nH]c2ccccc12)c1cn2cc(-c3csc4ccccc34)nc(CCCN)c2n1	10.1016/s0960-894x(01)00051-8
	142471961	190816	0	None	-275	2	Human	5.4	pKi	=	5.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	494	10	2	5	5.4	FC(F)(F)Oc1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5192791	190816	0	None	-275	2	Human	5.4	pKi	=	5.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	494	10	2	5	5.4	FC(F)(F)Oc1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	91809285	125228	0	None	-323	6	Human	7.4	pKi	=	7.4	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1880	34	19	19	5.8	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647686	125228	0	None	-323	6	Human	7.4	pKi	=	7.4	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1880	34	19	19	5.8	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	91809301	125242	0	None	-831	4	Human	7.4	pKi	=	7.4	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1470	22	17	16	2.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647700	125242	0	None	-831	4	Human	7.4	pKi	=	7.4	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1470	22	17	16	2.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	9985523	98691	0	None	-2	5	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	572	17	2	6	6.2	NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)C[C@@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL281200	98691	0	None	-2	5	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	572	17	2	6	6.2	NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)C[C@@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL408987	210983	0	None	-2	5	Human	6.4	pKi	=	6.4	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC(=O)CNC1=O	10.1021/jm9806289
	CHEMBL410181	211048	0	None	-1	5	Human	6.4	pKi	=	6.4	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)C[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	9848232	101670	0	None	-6	3	Human	5.4	pKi	=	5.4	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	485	8	4	3	3.7	NCCCCNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(C=Cc3ccccc32)CC1	10.1021/jm980194h
	CHEMBL302567	101670	0	None	-6	3	Human	5.4	pKi	=	5.4	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	485	8	4	3	3.7	NCCCCNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(C=Cc3ccccc32)CC1	10.1021/jm980194h
	142471733	189961	0	None	-75	2	Human	5.4	pKi	=	5.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	394	7	2	4	4.4	CC(C)(C)Cc1nnc(Cc2c[nH]c3cc(F)ccc23)n1CCCc1c[nH]cn1	10.1039/D1MD00044F
	CHEMBL5180116	189961	0	None	-75	2	Human	5.4	pKi	=	5.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	394	7	2	4	4.4	CC(C)(C)Cc1nnc(Cc2c[nH]c3cc(F)ccc23)n1CCCc1c[nH]cn1	10.1039/D1MD00044F
	CHEMBL407195	210889	0	None	-21	4	Human	6.4	pKi	=	6.4	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(F)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc(F)cc2)C(N)=O)NC1=O	10.1021/jm9806289
	10699714	98945	0	None	-2	5	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	678	20	2	7	7.4	NCCCCCOC[C@@H]1O[C@H](OCCc2c[nH]c3ccccc23)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL282803	98945	0	None	-2	5	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	678	20	2	7	7.4	NCCCCCOC[C@@H]1O[C@H](OCCc2c[nH]c3ccccc23)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	73348312	88794	0	None	-4897	2	Human	5.4	pKi	=	5.4	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	410	3	3	2	6.2	CC1(C2CCCCC2)N[C@H](c2nc(-c3ccccc3)c[nH]2)Cc2c1[nH]c1ccccc21	10.1021/jm0108449
	CHEMBL2367844	88794	0	None	-4897	2	Human	5.4	pKi	=	5.4	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	410	3	3	2	6.2	CC1(C2CCCCC2)N[C@H](c2nc(-c3ccccc3)c[nH]2)Cc2c1[nH]c1ccccc21	10.1021/jm0108449
	CHEMBL439005	212059	0	None	-8	4	Human	6.4	pKi	=	6.4	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	168274800	189489	0	None	-630	2	Human	6.4	pKi	=	6.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	9	2	6	3.8	CS(=O)(=O)c1cccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5172814	189489	0	None	-630	2	Human	6.4	pKi	=	6.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	9	2	6	3.8	CS(=O)(=O)c1cccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	16062816	5972	0	None	-1479	5	Human	5.4	pKi	=	5.4	Binding	Displacement of SST14 from human recombinant SST1 receptorDisplacement of SST14 from human recombinant SST1 receptor	ChEMBL	473	9	2	7	5.1	CCOc1cc(CN2CCC(Nc3nc4cc(C(=O)O)ccc4o3)CC2)cc(OCC)c1Cl	10.1016/j.bmcl.2009.09.024
	CHEMBL1080585	5972	0	None	-1479	5	Human	5.4	pKi	=	5.4	Binding	Displacement of SST14 from human recombinant SST1 receptorDisplacement of SST14 from human recombinant SST1 receptor	ChEMBL	473	9	2	7	5.1	CCOc1cc(CN2CCC(Nc3nc4cc(C(=O)O)ccc4o3)CC2)cc(OCC)c1Cl	10.1016/j.bmcl.2009.09.024
	86294248	118302	1	None	-1023	2	Human	5.3	pKi	=	5.3	Binding	Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 minsDisplacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mins	ChEMBL	298	3	2	4	1.4	Cn1nc(C(C)(C)NC(=O)[C@@H]2[C@H]3CNC[C@H]32)c2ccccc21	10.1021/ml500538a
	CHEMBL3421843	118302	1	None	-1023	2	Human	5.3	pKi	=	5.3	Binding	Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 minsDisplacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mins	ChEMBL	298	3	2	4	1.4	Cn1nc(C(C)(C)NC(=O)[C@@H]2[C@H]3CNC[C@H]32)c2ccccc21	10.1021/ml500538a
	71458043	78478	0	None	-3	5	Human	5.3	pKi	=	5.3	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	494	10	3	5	4.3	CC(C)(C(=O)NCCc1c[nH]c2ccccc12)c1cn2cc(Cc3ccccc3)nc(CCCN)c2n1	10.1016/s0960-894x(01)00051-8
	CHEMBL2112934	78478	0	None	-3	5	Human	5.3	pKi	=	5.3	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	494	10	3	5	4.3	CC(C)(C(=O)NCCc1c[nH]c2ccccc12)c1cn2cc(Cc3ccccc3)nc(CCCN)c2n1	10.1016/s0960-894x(01)00051-8
	142471924	189790	0	None	-524	3	Human	6.3	pKi	=	6.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	432	8	2	4	4.6	Fc1ccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5177573	189790	0	None	-524	3	Human	6.3	pKi	=	6.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	432	8	2	4	4.6	Fc1ccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	91809300	125241	0	None	-602	4	Human	7.3	pKi	=	7.3	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1454	22	16	15	2.7	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647699	125241	0	None	-602	4	Human	7.3	pKi	=	7.3	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1454	22	16	15	2.7	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	142471772	190574	0	None	-870	2	Human	5.3	pKi	=	5.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	488	9	2	4	5.3	Brc1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5189042	190574	0	None	-870	2	Human	5.3	pKi	=	5.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	488	9	2	4	5.3	Brc1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	56945132	170844	0	None	-251	3	Human	5.3	pKi	=	5.3	Binding	Displacement of [125I]-Tyr-SRIF from SST1 receptor (unknown origin) after 90 mins by gamma counting methodDisplacement of [125I]-Tyr-SRIF from SST1 receptor (unknown origin) after 90 mins by gamma counting method	ChEMBL	478	9	2	4	5.8	Clc1ccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1Cl	10.1039/C8MD00388B
	CHEMBL4462793	170844	0	None	-251	3	Human	5.3	pKi	=	5.3	Binding	Displacement of [125I]-Tyr-SRIF from SST1 receptor (unknown origin) after 90 mins by gamma counting methodDisplacement of [125I]-Tyr-SRIF from SST1 receptor (unknown origin) after 90 mins by gamma counting method	ChEMBL	478	9	2	4	5.8	Clc1ccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1Cl	10.1039/C8MD00388B
	CHEMBL415201	211422	0	None	-13	4	Human	6.3	pKi	=	6.3	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(F)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	46882133	5716	0	None	-27	7	Human	5.3	pKi	=	5.3	Binding	Displacement of SST14 from human recombinant SST1 receptorDisplacement of SST14 from human recombinant SST1 receptor	ChEMBL	478	9	2	7	5.1	CCOc1cc(CN2CCC(Nc3nc4cc(NC(=O)C5CCC5)ccc4o3)CC2)ccc1OC	10.1016/j.bmcl.2009.09.024
	CHEMBL1078896	5716	0	None	-27	7	Human	5.3	pKi	=	5.3	Binding	Displacement of SST14 from human recombinant SST1 receptorDisplacement of SST14 from human recombinant SST1 receptor	ChEMBL	478	9	2	7	5.1	CCOc1cc(CN2CCC(Nc3nc4cc(NC(=O)C5CCC5)ccc4o3)CC2)ccc1OC	10.1016/j.bmcl.2009.09.024
	91809308	125249	0	None	-15	4	Human	8.3	pKi	=	8.3	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1602	27	18	16	4.2	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647707	125249	0	None	-15	4	Human	8.3	pKi	=	8.3	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1602	27	18	16	4.2	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	9857566	59730	0	None	-	1	Human	5.3	pKi	=	5.3	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	302	4	3	2	3.8	N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	CHEMBL173715	59730	0	None	-	1	Human	5.3	pKi	=	5.3	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	302	4	3	2	3.8	N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	CHEMBL1201185	206849	17	None	-1000	4	Human	6.3	pKi	=	6.3	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm021093t
	11963995	91419	0	None	-295	3	Human	5.3	pKi	=	5.3	Binding	Binding affinity to human SST1RBinding affinity to human SST1R	ChEMBL	387	6	1	4	3.8	CCOc1cc(CN2CCC(NC(=O)c3cncc(C)c3)CC2)ccc1Cl	10.1021/jm701144e
	CHEMBL241329	91419	0	None	-295	3	Human	5.3	pKi	=	5.3	Binding	Binding affinity to human SST1RBinding affinity to human SST1R	ChEMBL	387	6	1	4	3.8	CCOc1cc(CN2CCC(NC(=O)c3cncc(C)c3)CC2)ccc1Cl	10.1021/jm701144e
	CHEMBL413171	211293	0	None	-4	5	Human	6.3	pKi	=	6.3	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(F)c(F)c(F)c(F)c2F)CSSC[C@H](C(=O)N[C@@H](Cc2c(F)c(F)c(F)c(F)c2F)C(N)=O)NC1=O	10.1021/jm9806289
	11705763	167741	0	None	-1380	5	Human	6.3	pKi	=	6.3	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	484	10	2	7	5.4	Cc1cccc2c(C(=O)CCSc3nnc(-c4ccc5ccccc5n4)n3CCCCN)c[nH]c12	10.1016/j.bmcl.2005.05.061
	CHEMBL434159	167741	0	None	-1380	5	Human	6.3	pKi	=	6.3	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	484	10	2	7	5.4	Cc1cccc2c(C(=O)CCSc3nnc(-c4ccc5ccccc5n4)n3CCCCN)c[nH]c12	10.1016/j.bmcl.2005.05.061
	142471677	191342	0	None	-1621	2	Human	5.3	pKi	=	5.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	478	9	2	4	5.5	FC(F)(F)c1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5200786	191342	0	None	-1621	2	Human	5.3	pKi	=	5.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	478	9	2	4	5.5	FC(F)(F)c1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	44308836	102305	0	None	-134	5	Human	6.3	pKi	=	6.3	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	539	7	4	3	4.7	NCC1CCCC(CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(C=Cc4ccccc43)CC2)C1	10.1021/jm980194h
	CHEMBL305279	102305	0	None	-134	5	Human	6.3	pKi	=	6.3	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	539	7	4	3	4.7	NCC1CCCC(CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(C=Cc4ccccc43)CC2)C1	10.1021/jm980194h
	9827283	78163	0	None	-117	4	Human	5.3	pKi	=	5.3	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	499	9	4	3	4.1	NCCCCCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(C=Cc3ccccc32)CC1	10.1021/jm980194h
	CHEMBL2112223	78163	0	None	-117	4	Human	5.3	pKi	=	5.3	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	499	9	4	3	4.1	NCCCCCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(C=Cc3ccccc32)CC1	10.1021/jm980194h
	142471936	190889	0	None	-776	5	Human	6.3	pKi	=	6.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	482	8	2	4	5.5	Fc1ccc2c(Cc3nnc(Cc4cccc(C(F)(F)F)c4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL5193727	190889	0	None	-776	5	Human	6.3	pKi	=	6.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	482	8	2	4	5.5	Fc1ccc2c(Cc3nnc(Cc4cccc(C(F)(F)F)c4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL437057	211945	0	None	-3	3	Human	6.3	pKi	=	6.3	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(F)c(F)c(F)c(F)c2F)CSSC[C@H](C(=O)N[C@@H](Cc2c(F)c(F)c(F)c(F)c2F)C(N)=O)NC1=O	10.1021/jm9806289
	CHEMBL264028	208848	0	None	-32	5	Human	6.2	pKi	=	6.2	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(I)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc(I)cc2)C(N)=O)NC1=O	10.1021/jm9806289
	44397389	123513	0	None	-33	5	Human	7.2	pKi	=	7.2	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	460	9	2	6	5.2	NCCCCn1c(SCCc2c[nH]c3cc(F)ccc23)nnc1-c1ccc2ccccc2n1	10.1016/j.bmcl.2005.05.061
	CHEMBL363092	123513	0	None	-33	5	Human	7.2	pKi	=	7.2	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	460	9	2	6	5.2	NCCCCn1c(SCCc2c[nH]c3cc(F)ccc23)nnc1-c1ccc2ccccc2n1	10.1016/j.bmcl.2005.05.061
	142471730	189781	0	None	-741	3	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	464	8	2	4	5.3	FC(F)(F)c1cccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5177487	189781	0	None	-741	3	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	464	8	2	4	5.3	FC(F)(F)c1cccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	91809302	125243	0	None	-26	3	Human	7.2	pKi	=	7.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1439	23	16	14	3.7	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647701	125243	0	None	-26	3	Human	7.2	pKi	=	7.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1439	23	16	14	3.7	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	91809291	125232	0	None	-120	4	Human	8.2	pKi	=	8.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1473	23	16	14	2.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCC[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL3647690	125232	0	None	-120	4	Human	8.2	pKi	=	8.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1473	23	16	14	2.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCC[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	2018	2946	22	None	-50	4	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	9941444	2946	22	None	-50	4	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	CHEMBL3349607	2946	22	None	-50	4	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	DB06663	2946	22	None	-50	4	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	CHEMBL3349524	209667	0	None	-10	4	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL3349604	209677	0	None	-15	5	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]2C[C@@H](OC(=O)NCCN)CN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC1=O	10.1021/jm021093t
	91809286	125229	0	None	-41	6	Human	8.2	pKi	=	8.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1489	23	16	15	2.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCS(=O)(=O)C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL3647687	125229	0	None	-41	6	Human	8.2	pKi	=	8.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1489	23	16	15	2.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCS(=O)(=O)C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL411556	211129	0	None	1	4	Human	7.2	pKi	=	7.2	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2cccc(F)c2)CSSC[C@@H](C(=O)N[C@@H](Cc2cccc(F)c2)C(N)=O)NC1=O	10.1021/jm9806289
	142471891	189991	0	None	-436	4	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	430	8	2	4	5.0	Clc1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5180551	189991	0	None	-436	4	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	430	8	2	4	5.0	Clc1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL3349599	209672	0	None	-199	5	Human	7.2	pKi	=	7.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC1=O	10.1021/jm021093t
	CHEMBL421362	211516	0	None	-1258	5	Human	6.2	pKi	=	6.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm021093t
	91809292	125233	0	None	-3235	4	Human	7.2	pKi	=	7.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1619	27	18	17	2.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647691	125233	0	None	-3235	4	Human	7.2	pKi	=	7.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1619	27	18	17	2.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	90644981	111308	0	None	-173	4	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]SS14 from human SST1 expressed in CHO membrane after 60 to 90 mins by scintillation countingDisplacement of [125I]SS14 from human SST1 expressed in CHO membrane after 60 to 90 mins by scintillation counting	ChEMBL	365	5	3	2	4.1	O=C(N[C@@H]1CCCC[C@@H]1NCc1c[nH]c2ccccc12)c1ccc(F)cc1	10.1021/ml500079u
	CHEMBL3287613	111308	0	None	-173	4	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]SS14 from human SST1 expressed in CHO membrane after 60 to 90 mins by scintillation countingDisplacement of [125I]SS14 from human SST1 expressed in CHO membrane after 60 to 90 mins by scintillation counting	ChEMBL	365	5	3	2	4.1	O=C(N[C@@H]1CCCC[C@@H]1NCc1c[nH]c2ccccc12)c1ccc(F)cc1	10.1021/ml500079u
	142471678	189439	0	None	-660	2	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	474	9	2	6	3.7	CS(=O)(=O)c1cccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5171935	189439	0	None	-660	2	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	474	9	2	6	3.7	CS(=O)(=O)c1cccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	10554930	99716	0	None	-2	5	Human	5.2	pKi	=	5.2	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	562	17	3	7	4.9	NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2c[nH]cn2)C[C@@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL28824	99716	0	None	-2	5	Human	5.2	pKi	=	5.2	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	562	17	3	7	4.9	NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2c[nH]cn2)C[C@@H]1OCc1ccccc1	10.1021/jm9800346
	91809296	125237	0	None	-34673	4	Human	6.2	pKi	=	6.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1488	23	17	17	1.5	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCS(=O)(=O)C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647695	125237	0	None	-34673	4	Human	6.2	pKi	=	6.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1488	23	17	17	1.5	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCS(=O)(=O)C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL414598	211388	0	None	1	4	Human	7.2	pKi	=	7.2	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(F)c(F)c(F)c(F)c2F)CSSC[C@@H](C(=O)N[C@@H](Cc2c(F)c(F)c(F)c(F)c2F)C(N)=O)NC1=O	10.1021/jm9806289
	142471767	191674	0	None	-1348	2	Human	5.2	pKi	=	5.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	4	5.1	Clc1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5205904	191674	0	None	-1348	2	Human	5.2	pKi	=	5.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	4	5.1	Clc1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	44363816	39422	0	None	-194	5	Human	6.2	pKi	=	6.2	Binding	In vitro binding affinity was evaluated against human Somatostatin receptor type 1 (hSSTR-1)In vitro binding affinity was evaluated against human Somatostatin receptor type 1 (hSSTR-1)	ChEMBL	589	14	3	5	5.0	C[C@@H](c1c[nH]c2ccccc12)[C@H](C(=O)N[C@H](CCCCN)C(=O)OC(C)(C)C)N1CCN(CCCc2ccccc2)C1=O	10.1016/s0960-894x(99)00016-5
	CHEMBL147499	39422	0	None	-194	5	Human	6.2	pKi	=	6.2	Binding	In vitro binding affinity was evaluated against human Somatostatin receptor type 1 (hSSTR-1)In vitro binding affinity was evaluated against human Somatostatin receptor type 1 (hSSTR-1)	ChEMBL	589	14	3	5	5.0	C[C@@H](c1c[nH]c2ccccc12)[C@H](C(=O)N[C@H](CCCCN)C(=O)OC(C)(C)C)N1CCN(CCCc2ccccc2)C1=O	10.1016/s0960-894x(99)00016-5
	CHEMBL2372959	208570	0	None	-2	5	Human	6.1	pKi	=	6.1	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)C2Cc3ccccc3C2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)C2Cc3ccccc3C2)NC1=O	10.1021/jm9806289
	117711399	118304	0	None	-104	2	Human	5.1	pKi	=	5.1	Binding	Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 minsDisplacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mins	ChEMBL	310	3	2	4	1.8	Cc1nc(C(C)(C)NC(=O)[C@@H]2[C@H]3CNC[C@H]32)c2ccccc2n1	10.1021/ml500538a
	CHEMBL3421845	118304	0	None	-104	2	Human	5.1	pKi	=	5.1	Binding	Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 minsDisplacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mins	ChEMBL	310	3	2	4	1.8	Cc1nc(C(C)(C)NC(=O)[C@@H]2[C@H]3CNC[C@H]32)c2ccccc2n1	10.1021/ml500538a
	91809290	125231	0	None	-213	4	Human	8.1	pKi	=	8.1	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1636	27	18	16	3.3	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL3647689	125231	0	None	-213	4	Human	8.1	pKi	=	8.1	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1636	27	18	16	3.3	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL406152	210839	0	None	1	4	Human	7.1	pKi	=	7.1	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2cccc(F)c2)CSSC[C@H](C(=O)N[C@@H](Cc2cccc(F)c2)C(N)=O)NC1=O	10.1021/jm9806289
	90665461	108761	0	None	-4	5	Human	5.1	pKi	=	5.1	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	807	13	3	7	4.3	C[C@@H](O)CN1CCC(=O)N(Cc2ccccc2)CCC(=O)N(Cc2ccccc2)CCC(=O)N(CCc2c[nH]c3ccccc23)CCC(=O)N(CCCCN)CCC1=O	10.1039/C2MD20265D
	CHEMBL3218123	108761	0	None	-4	5	Human	5.1	pKi	=	5.1	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	807	13	3	7	4.3	C[C@@H](O)CN1CCC(=O)N(Cc2ccccc2)CCC(=O)N(Cc2ccccc2)CCC(=O)N(CCc2c[nH]c3ccccc23)CCC(=O)N(CCCCN)CCC1=O	10.1039/C2MD20265D
	CHEMBL406738	210861	0	None	-11	5	Human	6.1	pKi	=	6.1	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)CC[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	86293506	118301	0	None	-229	2	Human	6.1	pKi	=	6.1	Binding	Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 minsDisplacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mins	ChEMBL	309	3	2	3	2.4	Cc1cc2ccccc2c(C(C)(C)NC(=O)[C@@H]2[C@H]3CNC[C@H]32)n1	10.1021/ml500538a
	CHEMBL3421842	118301	0	None	-229	2	Human	6.1	pKi	=	6.1	Binding	Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 minsDisplacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mins	ChEMBL	309	3	2	3	2.4	Cc1cc2ccccc2c(C(C)(C)NC(=O)[C@@H]2[C@H]3CNC[C@H]32)n1	10.1021/ml500538a
	168275406	189703	0	None	-794	4	Human	6.1	pKi	=	6.1	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	482	8	2	4	5.7	Fc1ccc2c(Cc3nnc(Cc4ccc(Cl)c(Cl)c4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL5176083	189703	0	None	-794	4	Human	6.1	pKi	=	6.1	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	482	8	2	4	5.7	Fc1ccc2c(Cc3nnc(Cc4ccc(Cl)c(Cl)c4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	13690207	114870	0	None	-812	5	Human	6.1	pKi	=	6.1	Binding	Binding affinity towards somatostatin receptor type 1Binding affinity towards somatostatin receptor type 1	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1021/jm050376t
	CHEMBL3350037	114870	0	None	-812	5	Human	6.1	pKi	=	6.1	Binding	Binding affinity towards somatostatin receptor type 1Binding affinity towards somatostatin receptor type 1	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1021/jm050376t
	91809276	125219	0	None	-26	6	Human	8.1	pKi	=	8.1	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1620	27	18	16	4.3	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL3647677	125219	0	None	-26	6	Human	8.1	pKi	=	8.1	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1620	27	18	16	4.3	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	91809294	125235	0	None	-1148	4	Human	7.0	pKi	=	7.0	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1912	34	19	19	3.8	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647693	125235	0	None	-1148	4	Human	7.0	pKi	=	7.0	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1912	34	19	19	3.8	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	44385591	130852	0	None	-38	2	Human	5.0	pKi	=	5.0	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	488	7	3	2	6.2	O=C(Cc1cccc(C(F)(F)F)c1)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	CHEMBL368993	130852	0	None	-38	2	Human	5.0	pKi	=	5.0	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	488	7	3	2	6.2	O=C(Cc1cccc(C(F)(F)F)c1)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	142471832	189671	0	None	-138	5	Human	7.0	pKi	=	7.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	471	8	3	4	5.1	Fc1ccc2c(Cc3nnc(Cc4c[nH]c5cc(F)ccc45)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL5175637	189671	0	None	-138	5	Human	7.0	pKi	=	7.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	471	8	3	4	5.1	Fc1ccc2c(Cc3nnc(Cc4c[nH]c5cc(F)ccc45)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	10096510	57112	0	None	-26	4	Human	5.0	pKi	=	5.0	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	475	7	2	6	5.2	CC(C)(C(=O)NC1CCCCC1)c1cn2cc(-c3csc4ccccc34)nc(CCCN)c2n1	10.1016/s0960-894x(01)00051-8
	CHEMBL165402	57112	0	None	-26	4	Human	5.0	pKi	=	5.0	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	475	7	2	6	5.2	CC(C)(C(=O)NC1CCCCC1)c1cn2cc(-c3csc4ccccc34)nc(CCCN)c2n1	10.1016/s0960-894x(01)00051-8
	168279197	190328	0	None	-1621	4	Human	6.0	pKi	=	6.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	5	4.4	COc1cccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5185547	190328	0	None	-1621	4	Human	6.0	pKi	=	6.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	5	4.4	COc1cccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	91809288	125230	0	None	-562	6	Human	7.0	pKi	=	7	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1472	23	17	16	1.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCC[S@@+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647688	125230	0	None	-562	6	Human	7.0	pKi	=	7	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1472	23	17	16	1.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCC[S@@+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	91809312	125253	0	None	-588	3	Human	7.0	pKi	=	7	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1754	28	17	18	6.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N(CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647711	125253	0	None	-588	3	Human	7.0	pKi	=	7	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1754	28	17	18	6.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N(CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	2030	3602	7	None	-13	10	Human	8.1	pKd	=	8.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	15135911
	5311377	3602	7	None	-13	10	Human	8.1	pKd	=	8.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	15135911
	CHEMBL251541	3602	7	None	-13	10	Human	8.1	pKd	=	8.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	15135911
	16161315	214315	0	125I-CGP23996	-6	13	Human	10.0	pKi	=	10	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-Tyr11-SRIF	-6	13	Human	10.0	pKi	=	10	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	UNDEFINED	-6	13	Human	10.0	pKi	=	10	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-Tyr11-somatostatin	-3	13	Rat	10.0	pKi	=	10	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-Tyr11-somatostatin-14	-3	13	Rat	9.7	pKi	=	9.7	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-Tyr11-SRIF-14	-6	13	Human	9.5	pKi	=	9.5	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-LTT-SST-28	-6	13	Human	9.4	pKi	=	9.4	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-LTT-SST-28	-6	13	Human	9.4	pKi	=	9.4	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-Tyr11-SRIF	-6	13	Human	9.3	pKi	=	9.3	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-SOMATOSTATIN 14	-6	13	Human	9.2	pKi	=	9.2	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-SRIF	-6	13	Human	9.2	pKi	=	9.2	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-SRIF-28	-6	13	Human	9.2	pKi	=	9.2	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-LTT-SRIF28	-6	13	Human	9.1	pKi	=	9.1	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-LTT-SRIF28	-6	13	Human	9.1	pKi	=	9.1	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-Tyr11-SRIF	-6	13	Human	9.1	pKi	=	9.1	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-Tyr10-CST14	-6	13	Human	9.1	pKi	=	9.1	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-Tyr11-somatostatin-14	-6	13	Human	9.0	pKi	=	9	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-LTT-SST-28	-6	13	Human	9.0	pKi	=	9.0	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-CGP23996	-6	13	Human	9.0	pKi	=	9.0	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	2055	2851	43	125I-CGP23996	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	2851	43	125I-LTT-SST-28	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	2851	43	125I-Tyr11-SRIF	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	2851	43	125I-Tyr11-somatostatin-14	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-CGP23996	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-LTT-SST-28	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-Tyr11-SRIF	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-Tyr11-somatostatin-14	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-CGP23996	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-LTT-SST-28	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-Tyr11-SRIF	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-Tyr11-somatostatin-14	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-CGP23996	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-LTT-SST-28	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-Tyr11-SRIF	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-Tyr11-somatostatin-14	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-CGP23996	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-LTT-SST-28	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-Tyr11-SRIF	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-Tyr11-somatostatin-14	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-CGP23996	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-LTT-SST-28	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-Tyr11-SRIF	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-Tyr11-somatostatin-14	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	3899	11	125I-LTT-SST-28	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	3899	11	UNDEFINED	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	3899	11	125I-LTT-SST-28	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	3899	11	UNDEFINED	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	3899	11	125I-LTT-SST-28	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	3899	11	UNDEFINED	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	3899	11	125I-LTT-SST-28	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	3899	11	UNDEFINED	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	3899	11	125I-LTT-SST-28	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	3899	11	UNDEFINED	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	214316	0	125I-CGP23996	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	214316	0	125I-LTT-SST-28	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	214316	0	125I-SOMATOSTATIN	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	214316	0	125I-SRIF	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	214316	0	125I-SRIF-28	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	214316	0	125I-Tyr11-SRIF	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	214316	0	125I-Tyr11-somatostatin-14	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	13105142	214317	0	UNDEFINED	-30199	5	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	808	11	8	8	2.0	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O	None
	None	214316	0	125I-LTT-SST-28	-19054	12	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	214316	0	125I-Tyr11-SRIF	-19054	12	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	13105142	214317	0	125I-CGP23996	-30199	5	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	808	11	8	8	2.0	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O	None
	13105142	214317	0	125I-LTT-SRIF28	-30199	5	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	808	11	8	8	2.0	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O	None
	13105142	214317	0	125I-Tyr10-CST14	-30199	5	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	808	11	8	8	2.0	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O	None
	None	214587	0	125I-LTT-SST-28	-93	5	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	584	17	5	8	2.8	CCCCC(C(=O)NC(CCCCN)C(=O)OC)NC(=O)NC(CC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-]	None
	2054	3899	11	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	3899	11	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	3899	11	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	3899	11	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	3899	11	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	3899	11	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	3899	11	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	3899	11	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	3899	11	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	3899	11	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	2851	43	125I-Tyr11-somatostatin-14	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-Tyr11-somatostatin-14	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-Tyr11-somatostatin-14	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-Tyr11-somatostatin-14	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-Tyr11-somatostatin-14	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-Tyr11-somatostatin-14	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	2851	43	125I-Tyr11-SRIF	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-Tyr11-SRIF	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-Tyr11-SRIF	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-Tyr11-SRIF	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-Tyr11-SRIF	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-Tyr11-SRIF	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	214587	0	125I-LTT-SST-28	-93	5	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase	584	17	5	8	2.8	CCCCC(C(=O)NC(CCCCN)C(=O)OC)NC(=O)NC(CC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-]	None
	None	214587	0	UNDEFINED	-93	5	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase	584	17	5	8	2.8	CCCCC(C(=O)NC(CCCCN)C(=O)OC)NC(=O)NC(CC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-]	None
	2054	3899	11	125I-SRIF-28	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	3899	11	125I-Tyr11-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	3899	11	125I-SRIF-28	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	3899	11	125I-Tyr11-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	3899	11	125I-SRIF-28	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	3899	11	125I-Tyr11-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	3899	11	125I-SRIF-28	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	3899	11	125I-Tyr11-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	3899	11	125I-SRIF-28	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	3899	11	125I-Tyr11-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	3899	11	125I-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	3899	11	125I-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	3899	11	125I-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	3899	11	125I-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	3899	11	125I-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	214585	0	125I-Tyr11-somatostatin-14	-112	9	Human	7.7	pKi	=	7.7	Binding	NoneNone	PDSP KiDatabase	1077	14	12	13	0.6	CC(C1C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)N)C(=O)N)CC6=CC=CC=C6)O	None
	None	214585	0	UNDEFINED	-112	9	Human	7.7	pKi	=	7.7	Binding	NoneNone	PDSP KiDatabase	1077	14	12	13	0.6	CC(C1C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)N)C(=O)N)CC6=CC=CC=C6)O	None
	None	214588	0	125I-LTT-SST-28	-537	5	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase	485	11	4	4	3.1	COC(=O)C(CCCN=C(N)N)NC(=O)CCCC1=C(NC2=C(C=C(C=C12)F)F)C3=CC=CC=C3	None
	None	214588	0	UNDEFINED	-537	5	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase	485	11	4	4	3.1	COC(=O)C(CCCN=C(N)N)NC(=O)CCCC1=C(NC2=C(C=C(C=C12)F)F)C3=CC=CC=C3	None
	16161315	214315	0	125I-Tyr11-SRIF	-6	13	Human	8.7	pKi	=	8.7	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-Tyr11-somatostatin-14	-6	13	Human	8.7	pKi	=	8.7	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-SOMATOSTATIN	-6	13	Human	8.7	pKi	=	8.7	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	214315	0	125I-Tyr11-somatostatin-14	-6	13	Human	8.7	pKi	=	8.7	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	2055	2851	43	125I-LTT-SRIF28	-1047	14	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-LTT-SRIF28	-1047	14	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-LTT-SRIF28	-1047	14	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-LTT-SRIF28	-1047	14	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-LTT-SRIF28	-1047	14	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-LTT-SRIF28	-1047	14	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	3899	11	125I-CGP23996	-741	11	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	3899	11	125I-CGP23996	-741	11	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	3899	11	125I-CGP23996	-741	11	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	3899	11	125I-CGP23996	-741	11	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	3899	11	125I-CGP23996	-741	11	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	2851	43	125I-LTT-SST-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-LTT-SST-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-LTT-SST-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-LTT-SST-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-LTT-SST-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-LTT-SST-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	2851	43	125I-SRIF-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-SRIF-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-SRIF-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-SRIF-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-SRIF-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-SRIF-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	2851	43	125I-SOMATOSTATIN 14	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	2851	43	125I-SRIF	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-SOMATOSTATIN 14	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-SRIF	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-SOMATOSTATIN 14	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-SRIF	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-SOMATOSTATIN 14	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-SRIF	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-SOMATOSTATIN 14	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-SRIF	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-SOMATOSTATIN 14	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-SRIF	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	214586	0	125I-LTT-SST-28	-54954	5	Human	5.6	pKi	=	5.6	Binding	NoneNone	PDSP KiDatabase	585	8	5	5	4.2	CC(C1=CNC2=CC=CC=C21)C(C(=O)NCC3CCCC(C3)CN)NC(=O)N4CCC(CC4)N5C6=CC=CC=C6NC5=O	None
	None	214586	0	UNDEFINED	-54954	5	Human	5.6	pKi	=	5.6	Binding	NoneNone	PDSP KiDatabase	585	8	5	5	4.2	CC(C1=CNC2=CC=CC=C21)C(C(=O)NCC3CCCC(C3)CN)NC(=O)N4CCC(CC4)N5C6=CC=CC=C6NC5=O	None
	2055	2851	43	UNDEFINED	-1047	14	Human	6.5	pKi	=	6.5	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	UNDEFINED	-1047	14	Human	6.5	pKi	=	6.5	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	UNDEFINED	-1047	14	Human	6.5	pKi	=	6.5	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	UNDEFINED	-1047	14	Human	6.5	pKi	=	6.5	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	UNDEFINED	-1047	14	Human	6.5	pKi	=	6.5	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	UNDEFINED	-1047	14	Human	6.5	pKi	=	6.5	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	214589	0	125I-LTT-SST-28	-4	5	Human	8.5	pKi	=	8.5	Binding	NoneNone	PDSP KiDatabase	536	11	4	5	5.2	CC(COC(=O)C(CCCCN)NC(=O)CC1=C(NC2=C1C=CC3=CC=CC=C32)C4=CC5=CC=CC=C5C=C4)N	None
	None	214589	0	UNDEFINED	-4	5	Human	8.5	pKi	=	8.5	Binding	NoneNone	PDSP KiDatabase	536	11	4	5	5.2	CC(COC(=O)C(CCCCN)NC(=O)CC1=C(NC2=C1C=CC3=CC=CC=C32)C4=CC5=CC=CC=C5C=C4)N	None
	2055	2851	43	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	2851	43	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	16161315	214315	0	125I-Tyr11-SRIF	-3	13	Rat	8.4	pKi	=	8.4	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	2054	3899	11	125I-SOMATOSTATIN	-741	11	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	3899	11	125I-SOMATOSTATIN	-741	11	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	3899	11	125I-SOMATOSTATIN	-741	11	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	3899	11	125I-SOMATOSTATIN	-741	11	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	3899	11	125I-SOMATOSTATIN	-741	11	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2031	2232	0	UNDEFINED	-851	9	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71349	2232	0	UNDEFINED	-851	9	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB06791	2232	0	UNDEFINED	-851	9	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	214744	0	125I-LTT-SST-28	-11220	5	Human	5.3	pKi	=	5.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	214585	0	125I-SOMATOSTATIN	-112	9	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase	1077	14	12	13	0.6	CC(C1C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)N)C(=O)N)CC6=CC=CC=C6)O	None
	2055	2851	43	125I-CGP23996	-1047	14	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-CGP23996	-1047	14	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-CGP23996	-1047	14	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-CGP23996	-1047	14	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-CGP23996	-1047	14	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-CGP23996	-1047	14	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	2851	43	None	-1047	14	Human	8.2	pKi	=	8.2	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	Drug Central		None	None	None		None	None
	383414	2851	43	None	-1047	14	Human	8.2	pKi	=	8.2	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	Drug Central		None	None	None		None	None
	90488715	2851	43	None	-1047	14	Human	8.2	pKi	=	8.2	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	Drug Central		None	None	None		None	None
	CHEMBL1680	2851	43	None	-1047	14	Human	8.2	pKi	=	8.2	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	Drug Central		None	None	None		None	None
	CHEMBL262746	2851	43	None	-1047	14	Human	8.2	pKi	=	8.2	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	Drug Central		None	None	None		None	None
	DB00104	2851	43	None	-1047	14	Human	8.2	pKi	=	8.2	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	Drug Central		None	None	None		None	None
	2054	3899	11	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	3899	11	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	3899	11	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	3899	11	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	3899	11	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	3899	11	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	3899	11	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	3899	11	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	3899	11	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	3899	11	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	2851	43	125I-SOMATOSTATIN	-1047	14	Human	6.1	pKi	=	6.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	2851	43	125I-SOMATOSTATIN	-1047	14	Human	6.1	pKi	=	6.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	2851	43	125I-SOMATOSTATIN	-1047	14	Human	6.1	pKi	=	6.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	2851	43	125I-SOMATOSTATIN	-1047	14	Human	6.1	pKi	=	6.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	2851	43	125I-SOMATOSTATIN	-1047	14	Human	6.1	pKi	=	6.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	2851	43	125I-SOMATOSTATIN	-1047	14	Human	6.1	pKi	=	6.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	16161315	214315	0	None	-6	13	Human	8.0	pKi	=	8.0	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	Drug Central	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	2028	1473	0	None	-2238	6	Human	5.2	pKi	=	5.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	12616335
	2029	2333	0	None	-281	6	Human	5.8	pKi	=	5.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	12616335
	2014	2175	0	None	-281	9	Human	6.2	pKi	=	6.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2014	2175	0	None	-281	9	Human	6.2	pKi	=	6.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2017	2693	0	None	-10	3	Human	7.4	pKi	=	7.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	16130961	876	0	None	-5	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	16130961	876	0	None	-5	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	16130961	876	0	None	-5	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2005	876	0	None	-5	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2005	876	0	None	-5	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	2005	876	0	None	-5	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2015	2217	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	607	16	3	4	6.2	NCCC(CC(CNC(=O)[C@@H](Cc1cccc2c1cccc2)NC(=O)N(CCc1ccccn1)CCc1ccccc1)(C)C)C	9784130
	9938757	2217	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	607	16	3	4	6.2	NCCC(CC(CNC(=O)[C@@H](Cc1cccc2c1cccc2)NC(=O)N(CCc1ccccn1)CCc1ccccc1)(C)C)C	9784130
	154734381	215975	0	None	1	9	Human	8.2	pKi	None	8.2	Binding	NoneNone	Drug Central	1095	17	13	14	0.8	CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@@H](N)CC1=CC=C2C=CC=CC2=C1	None
	2007	1143	0	None	-12	6	Human	8.4	pKi	None	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2007	1143	0	None	-12	6	Human	8.4	pKi	None	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2004	635	0	None	-4	7	Human	8.4	pKi	None	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2004	635	0	None	-4	7	Human	8.4	pKi	None	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	2004	635	0	None	-4	7	Human	8.4	pKi	None	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2016	2220	3	None	-7	2	Human	8.5	pKi	None	8.5	Binding	UnclassifiedUnclassified	Guide to Pharmacology	536	11	4	5	5.2	NCCCC[C@@H](C(=O)OC[C@@H](N)C)NC(=O)Cc1c([nH]c2c1ccc1c2cccc1)c1ccc2c(c1)cccc2	9784130
	5311375	2220	3	None	-7	2	Human	8.5	pKi	None	8.5	Binding	UnclassifiedUnclassified	Guide to Pharmacology	536	11	4	5	5.2	NCCCC[C@@H](C(=O)OC[C@@H](N)C)NC(=O)Cc1c([nH]c2c1ccc1c2cccc1)c1ccc2c(c1)cccc2	9784130
	CHEMBL252764	2220	3	None	-7	2	Human	8.5	pKi	None	8.5	Binding	UnclassifiedUnclassified	Guide to Pharmacology	536	11	4	5	5.2	NCCCC[C@@H](C(=O)OC[C@@H](N)C)NC(=O)Cc1c([nH]c2c1ccc1c2cccc1)c1ccc2c(c1)cccc2	9784130
	16133849	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	16133849	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	16133849	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	16133849	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	16133849	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	16133849	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2020	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2020	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	2020	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	2020	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	2020	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	2020	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	91935900	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	91935900	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	91935900	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	91935900	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	91935900	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	91935900	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	CHEMBL501796	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	CHEMBL501796	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	CHEMBL501796	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	CHEMBL501796	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	CHEMBL501796	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	CHEMBL501796	3606	10	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2019	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2019	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	11520208
	2019	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	2019	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	2019	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	2019	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	2019	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2019	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9724791
	2019	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9784130
	44386062	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	44386062	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	11520208
	44386062	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	44386062	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	44386062	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	44386062	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	44386062	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	44386062	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9724791
	44386062	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9784130
	CHEMBL440072	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	CHEMBL440072	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	11520208
	CHEMBL440072	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	CHEMBL440072	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	CHEMBL440072	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	CHEMBL440072	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	CHEMBL440072	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	CHEMBL440072	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9724791
	CHEMBL440072	3605	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9784130
	2008	1181	0	None	1	6	Human	9.4	pKi	None	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2008	1181	0	None	1	6	Human	9.4	pKi	None	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	2008	1181	0	None	1	6	Human	9.4	pKi	None	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799

Join us

Cite us

Main reference

Ligand source activities (1 row/activity)