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Ligand source activities (1 row/activity)

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Ligands					Receptor			Assay information							Chemical information
Sel. page	Common name	GPCRdb ID	#Vendors	Reference ligand	Fold selectivity (Potency)	# tested GPCRs (Potency)	Species	p-value (-log)	Type	Activity Relation	Activity Value	Assay Type	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI
	25174150	9014	0	None	64	2	Human	10.2	pIC50	=	10.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	582	18	2	6	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccncc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099326	9014	0	None	64	2	Human	10.2	pIC50	=	10.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	582	18	2	6	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccncc3)c2)c1CCC(=O)O	10.1021/jm1001919
	25191879	9023	0	None	-	1	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	599	18	2	5	8.0	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3cccc(F)c3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099335	9023	0	None	-	1	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	599	18	2	5	8.0	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3cccc(F)c3)c2)c1CCC(=O)O	10.1021/jm1001919
	25191880	9020	0	None	-	1	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	587	18	2	6	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099332	9020	0	None	-	1	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	587	18	2	6	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	25192021	9011	0	None	223	2	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	580	18	2	4	8.5	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099323	9011	0	None	223	2	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	580	18	2	4	8.5	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)c2)c1CCC(=O)O	10.1021/jm1001919
	25192023	8431	0	None	-	1	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	625	18	2	7	7.6	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1094346	8431	0	None	-	1	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	625	18	2	7	7.6	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	25192174	9019	0	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	586	18	2	5	8.5	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099331	9019	0	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	586	18	2	5	8.5	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	132379	111227	13	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonistic activity against LTB4 receptor using guinea pig (GP) spleen cell membraneAntagonistic activity against LTB4 receptor using guinea pig (GP) spleen cell membrane	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	CHEMBL328712	111227	13	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonistic activity against LTB4 receptor using guinea pig (GP) spleen cell membraneAntagonistic activity against LTB4 receptor using guinea pig (GP) spleen cell membrane	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	25192176	8432	0	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	626	18	2	8	7.0	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cncnc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1094347	8432	0	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	626	18	2	8	7.0	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cncnc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	25192175	9022	0	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	588	18	2	7	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cncnc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099334	9022	0	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	588	18	2	7	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cncnc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	25192022	3291	4	None	21	2	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	10.1021/jm1001919
	6158	3291	4	None	21	2	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	10.1021/jm1001919
	CHEMBL1098560	3291	4	None	21	2	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	10.1021/jm1001919
	23501721	9018	0	None	316	2	Human	9.3	pIC50	=	9.3	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	581	18	2	5	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)n2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099330	9018	0	None	316	2	Human	9.3	pIC50	=	9.3	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	581	18	2	5	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)n2)c1CCC(=O)O	10.1021/jm1001919
	25192325	9021	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	621	18	2	6	8.6	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccsc3)cc(-c3ccnc(Cl)c3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099333	9021	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	621	18	2	6	8.6	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccsc3)cc(-c3ccnc(Cl)c3)c2)c1CCC(=O)O	10.1021/jm1001919
	25192326	8927	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	592	18	2	6	8.6	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccsc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1098550	8927	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	592	18	2	6	8.6	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccsc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	25192327	9025	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	624	18	2	6	8.2	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099337	9025	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	624	18	2	6	8.2	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	25192468	8434	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	642	18	2	6	8.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc4c(c3)OCO4)cc(-c3ccccc3F)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1094349	8434	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	642	18	2	6	8.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc4c(c3)OCO4)cc(-c3ccccc3F)c2)c1CCC(=O)O	10.1021/jm1001919
	132379	111227	13	None	-	1	Human	9.1	pIC50	=	9.1	Functional	Concentration inhibiting 1 nM LTB4-induced aggregation in GP polymorphonuclear (PMN) leukocytes.Concentration inhibiting 1 nM LTB4-induced aggregation in GP polymorphonuclear (PMN) leukocytes.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	CHEMBL328712	111227	13	None	-	1	Human	9.1	pIC50	=	9.1	Functional	Concentration inhibiting 1 nM LTB4-induced aggregation in GP polymorphonuclear (PMN) leukocytes.Concentration inhibiting 1 nM LTB4-induced aggregation in GP polymorphonuclear (PMN) leukocytes.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	25192471	8433	0	None	15	2	Human	8.9	pIC50	=	8.9	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	642	18	2	6	8.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cccc(F)c3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1094348	8433	0	None	15	2	Human	8.9	pIC50	=	8.9	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	642	18	2	6	8.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cccc(F)c3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	10319829	25898	0	None	-	1	Human	7.0	pIC50	=	7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	417	11	1	3	6.9	CC(C)(CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL135612	25898	0	None	-	1	Human	7.0	pIC50	=	7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	417	11	1	3	6.9	CC(C)(CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10341135	29160	0	None	-	1	Human	7.0	pIC50	=	7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	403	10	1	3	6.5	CC(C)(CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL138380	29160	0	None	-	1	Human	7.0	pIC50	=	7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	403	10	1	3	6.5	CC(C)(CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10047140	27385	0	None	-	1	Human	6.0	pIC50	=	6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2cccc(Cl)c2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL136960	27385	0	None	-	1	Human	6.0	pIC50	=	6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2cccc(Cl)c2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	14946858	28933	0	None	-	1	Human	6.0	pIC50	=	6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	375	9	0	4	5.5	COC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL138174	28933	0	None	-	1	Human	6.0	pIC50	=	6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	375	9	0	4	5.5	COC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	6444688	186727	29	None	-	1	Human	6.0	pIC50	=	6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a008
	CHEMBL49302	186727	29	None	-	1	Human	6.0	pIC50	=	6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a008
	10071290	27875	0	None	-	1	Human	5.0	pIC50	=	5	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137303	27875	0	None	-	1	Human	5.0	pIC50	=	5	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	25192022	3291	4	None	21	2	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	10.1021/jm1001919
	6158	3291	4	None	21	2	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	10.1021/jm1001919
	CHEMBL1098560	3291	4	None	21	2	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	10.1021/jm1001919
	6444688	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Antagonistic activity against human polymorphonuclear (PMN) LTB4 receptorAntagonistic activity against human polymorphonuclear (PMN) LTB4 receptor	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00100a034
	CHEMBL49302	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Antagonistic activity against human polymorphonuclear (PMN) LTB4 receptorAntagonistic activity against human polymorphonuclear (PMN) LTB4 receptor	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00100a034
	10343923	27560	0	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	453	9	1	5	6.1	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137074	27560	0	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	453	9	1	5	6.1	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	10477988	27917	0	None	-	1	Human	6.9	pIC50	=	6.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	433	9	1	5	5.8	CC(C)(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137330	27917	0	None	-	1	Human	6.9	pIC50	=	6.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	433	9	1	5	5.8	CC(C)(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10364772	27934	0	None	-	1	Human	6.9	pIC50	=	6.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	419	9	1	5	5.4	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137341	27934	0	None	-	1	Human	6.9	pIC50	=	6.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	419	9	1	5	5.4	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	25192471	8433	0	None	15	2	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	642	18	2	6	8.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cccc(F)c3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1094348	8433	0	None	15	2	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	642	18	2	6	8.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cccc(F)c3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	6444688	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm960088k
	CHEMBL49302	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm960088k
	46888200	9024	0	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	637	18	3	4	9.1	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cccc(F)c3)cc(-c3ccc4[nH]ccc4c3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099336	9024	0	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	637	18	3	4	9.1	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cccc(F)c3)cc(-c3ccc4[nH]ccc4c3)c2)c1CCC(=O)O	10.1021/jm1001919
	10341242	27927	0	None	-	1	Human	5.9	pIC50	=	5.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	405	10	1	4	5.7	COc1cccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)c1	10.1021/jm00101a008
	CHEMBL137336	27927	0	None	-	1	Human	5.9	pIC50	=	5.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	405	10	1	4	5.7	COc1cccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)c1	10.1021/jm00101a008
	6450158	186581	14	None	-	1	Human	6.9	pIC50	=	6.9	Functional	The antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophilsThe antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1021/jm00064a006
	CHEMBL49210	186581	14	None	-	1	Human	6.9	pIC50	=	6.9	Functional	The antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophilsThe antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1021/jm00064a006
	46888199	9017	0	None	-	1	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	696	18	2	8	8.0	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc4c(c3)OCCO4)cc(-c3ccc4c(c3)OCCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099329	9017	0	None	-	1	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	696	18	2	8	8.0	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc4c(c3)OCCO4)cc(-c3ccc4c(c3)OCCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	114999	3469	15	None	-	1	Human	6.9	pIC50	=	6.9	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/0960-894X(95)00135-G
	6156	3469	15	None	-	1	Human	6.9	pIC50	=	6.9	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/0960-894X(95)00135-G
	CHEMBL14823	3469	15	None	-	1	Human	6.9	pIC50	=	6.9	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/0960-894X(95)00135-G
	44382384	59215	0	None	-	1	Human	4.9	pIC50	=	4.9	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL171666	59215	0	None	-	1	Human	4.9	pIC50	=	4.9	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	10092630	27598	0	None	-	1	Human	7.8	pIC50	=	7.8	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	404	9	2	4	5.7	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137104	27598	0	None	-	1	Human	7.8	pIC50	=	7.8	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	404	9	2	4	5.7	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10475503	27784	0	None	-	1	Human	7.8	pIC50	=	7.8	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	390	9	2	4	5.3	CC(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137247	27784	0	None	-	1	Human	7.8	pIC50	=	7.8	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	390	9	2	4	5.3	CC(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10023244	25942	1	None	-	1	Human	6.8	pIC50	=	6.8	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	389	9	1	3	6.1	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL135671	25942	1	None	-	1	Human	6.8	pIC50	=	6.8	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	389	9	1	3	6.1	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	44357534	26520	0	None	-	1	Human	6.7	pIC50	=	6.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	385	9	0	6	4.7	c1ccc(-c2cc(OCCCCCn3cnnn3)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136243	26520	0	None	-	1	Human	6.7	pIC50	=	6.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	385	9	0	6	4.7	c1ccc(-c2cc(OCCCCCn3cnnn3)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10406292	28169	0	None	-	1	Human	5.7	pIC50	=	5.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	361	9	1	3	5.4	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137504	28169	0	None	-	1	Human	5.7	pIC50	=	5.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	361	9	1	3	5.4	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	9865985	28446	0	None	-	1	Human	5.7	pIC50	=	5.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	405	9	1	5	5.2	O=C(O)CCCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137759	28446	0	None	-	1	Human	5.7	pIC50	=	5.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	405	9	1	5	5.2	O=C(O)CCCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10427789	27717	0	None	-	1	Human	4.7	pIC50	=	4.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	347	8	1	3	5.0	O=C(O)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137201	27717	0	None	-	1	Human	4.7	pIC50	=	4.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	347	8	1	3	5.0	O=C(O)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	23501721	9018	0	None	316	2	Human	6.7	pIC50	=	6.7	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	581	18	2	5	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)n2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099330	9018	0	None	316	2	Human	6.7	pIC50	=	6.7	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	581	18	2	5	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)n2)c1CCC(=O)O	10.1021/jm1001919
	9976757	28274	0	None	-	1	Human	7.7	pIC50	=	7.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	375	9	1	3	5.7	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137581	28274	0	None	-	1	Human	7.7	pIC50	=	7.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	375	9	1	3	5.7	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	44382378	58546	0	None	-	1	Human	6.7	pIC50	=	6.7	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL168854	58546	0	None	-	1	Human	6.7	pIC50	=	6.7	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	10474602	25759	0	None	-	1	Human	5.6	pIC50	=	5.6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	375	10	1	3	5.8	O=C(O)CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL135434	25759	0	None	-	1	Human	5.6	pIC50	=	5.6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	375	10	1	3	5.8	O=C(O)CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	46888201	9026	0	None	-	1	Human	8.5	pIC50	=	8.5	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	654	19	2	7	8.2	COc1ccc(-c2cc(OCCCCCCc3cccc(OCCCC(=O)O)c3CCC(=O)O)cc(-c3ccc4c(c3)OCO4)c2)cc1	10.1021/jm1001919
	CHEMBL1099338	9026	0	None	-	1	Human	8.5	pIC50	=	8.5	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	654	19	2	7	8.2	COc1ccc(-c2cc(OCCCCCCc3cccc(OCCCC(=O)O)c3CCC(=O)O)cc(-c3ccc4c(c3)OCO4)c2)cc1	10.1021/jm1001919
	3368	1146	18	None	-3	2	Mouse	7.5	pIC50	=	7.5	Functional	Tested for antagonistic activity in mouse spleen membrane against LTB4 receptorTested for antagonistic activity in mouse spleen membrane against LTB4 receptor	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	9867257	1146	18	None	-3	2	Mouse	7.5	pIC50	=	7.5	Functional	Tested for antagonistic activity in mouse spleen membrane against LTB4 receptorTested for antagonistic activity in mouse spleen membrane against LTB4 receptor	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	CHEMBL51770	1146	18	None	-3	2	Mouse	7.5	pIC50	=	7.5	Functional	Tested for antagonistic activity in mouse spleen membrane against LTB4 receptorTested for antagonistic activity in mouse spleen membrane against LTB4 receptor	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	10001576	28154	0	None	-	1	Human	5.5	pIC50	=	5.5	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccc(Cl)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137494	28154	0	None	-	1	Human	5.5	pIC50	=	5.5	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccc(Cl)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10046878	28206	0	None	-	1	Human	5.5	pIC50	=	5.5	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	405	10	1	4	5.7	COc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137531	28206	0	None	-	1	Human	5.5	pIC50	=	5.5	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	405	10	1	4	5.7	COc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	46888196	9013	0	None	-	1	Human	7.5	pIC50	=	7.5	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	640	20	2	6	8.5	COc1ccc(-c2cc(OCCCCCCc3cccc(OCCCC(=O)O)c3CCC(=O)O)cc(-c3ccc(OC)cc3)c2)cc1	10.1021/jm1001919
	CHEMBL1099325	9013	0	None	-	1	Human	7.5	pIC50	=	7.5	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	640	20	2	6	8.5	COc1ccc(-c2cc(OCCCCCCc3cccc(OCCCC(=O)O)c3CCC(=O)O)cc(-c3ccc(OC)cc3)c2)cc1	10.1021/jm1001919
	44382275	59410	0	None	-	1	Human	5.5	pIC50	=	5.5	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	C[C@@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL172457	59410	0	None	-	1	Human	5.5	pIC50	=	5.5	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	C[C@@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	25192021	9011	0	None	223	2	Human	7.4	pIC50	=	7.4	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	580	18	2	4	8.5	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099323	9011	0	None	223	2	Human	7.4	pIC50	=	7.4	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	580	18	2	4	8.5	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)c2)c1CCC(=O)O	10.1021/jm1001919
	44382276	119797	0	None	-	1	Human	4.4	pIC50	=	4.4	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL352814	119797	0	None	-	1	Human	4.4	pIC50	=	4.4	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	9978895	118458	0	None	-	1	Human	7.4	pIC50	=	7.4	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL342416	118458	0	None	-	1	Human	7.4	pIC50	=	7.4	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	10021742	9350	4	None	-	1	Human	5.3	pIC50	=	5.3	Functional	Antagonist activity at LTB4 receptor in fura-2 loaded human U937 cells assessed as inhibition of LTB4-induced calcium mobilizationAntagonist activity at LTB4 receptor in fura-2 loaded human U937 cells assessed as inhibition of LTB4-induced calcium mobilization	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	CHEMBL111825	9350	4	None	-	1	Human	5.3	pIC50	=	5.3	Functional	Antagonist activity at LTB4 receptor in fura-2 loaded human U937 cells assessed as inhibition of LTB4-induced calcium mobilizationAntagonist activity at LTB4 receptor in fura-2 loaded human U937 cells assessed as inhibition of LTB4-induced calcium mobilization	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	44356239	27619	0	None	-	1	Human	5.3	pIC50	=	5.3	Functional	Antagonistic activity in human polymorphonuclear (PMN) LTB4 receptorAntagonistic activity in human polymorphonuclear (PMN) LTB4 receptor	ChEMBL	361	8	0	2	4.9	CN(CCc1ccccc1)C(=O)CC1=CC=C(OCc2ccccc2)CC1	10.1021/jm00100a034
	CHEMBL137121	27619	0	None	-	1	Human	5.3	pIC50	=	5.3	Functional	Antagonistic activity in human polymorphonuclear (PMN) LTB4 receptorAntagonistic activity in human polymorphonuclear (PMN) LTB4 receptor	ChEMBL	361	8	0	2	4.9	CN(CCc1ccccc1)C(=O)CC1=CC=C(OCc2ccccc2)CC1	10.1021/jm00100a034
	46888197	9015	0	None	-	1	Human	8.3	pIC50	=	8.3	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	582	18	2	6	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3cncnc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099327	9015	0	None	-	1	Human	8.3	pIC50	=	8.3	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	582	18	2	6	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3cncnc3)c2)c1CCC(=O)O	10.1021/jm1001919
	46888198	9016	0	None	-	1	Human	8.3	pIC50	=	8.3	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	668	18	2	8	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc4c(c3)OCO4)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099328	9016	0	None	-	1	Human	8.3	pIC50	=	8.3	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	668	18	2	8	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc4c(c3)OCO4)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	9934323	99776	0	None	-	1	Human	6.3	pIC50	=	6.3	Functional	The antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophilsThe antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00064a006
	CHEMBL288758	99776	0	None	-	1	Human	6.3	pIC50	=	6.3	Functional	The antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophilsThe antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00064a006
	10091738	27580	0	None	-	1	Human	6.2	pIC50	=	6.2	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	389	9	1	3	6.0	Cc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137089	27580	0	None	-	1	Human	6.2	pIC50	=	6.2	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	389	9	1	3	6.0	Cc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	46888202	8435	0	None	-	1	Human	7.2	pIC50	=	7.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	656	18	2	6	8.4	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc(F)cc3)cc(-c3ccc4c(c3)OCCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1094350	8435	0	None	-	1	Human	7.2	pIC50	=	7.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	656	18	2	6	8.4	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc(F)cc3)cc(-c3ccc4c(c3)OCCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	44382468	58764	0	None	-	1	Human	5.2	pIC50	=	5.2	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	C[C@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL169639	58764	0	None	-	1	Human	5.2	pIC50	=	5.2	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	C[C@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	10430674	118820	0	None	-	1	Human	7.2	pIC50	=	7.2	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	393	9	1	3	5.8	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2F)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL344230	118820	0	None	-	1	Human	7.2	pIC50	=	7.2	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	393	9	1	3	5.8	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2F)n1)C(=O)O	10.1021/jm00101a008
	25174150	9014	0	None	64	2	Human	7.2	pIC50	=	7.2	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	582	18	2	6	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccncc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099326	9014	0	None	64	2	Human	7.2	pIC50	=	7.2	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	582	18	2	6	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccncc3)c2)c1CCC(=O)O	10.1021/jm1001919
	44357546	116240	0	None	-	1	Human	8.1	pIC50	=	8.1	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	399	9	0	6	5.2	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)n1cnnn1	10.1021/jm00101a008
	CHEMBL337563	116240	0	None	-	1	Human	8.1	pIC50	=	8.1	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	399	9	0	6	5.2	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)n1cnnn1	10.1021/jm00101a008
	46888195	9012	0	None	-	1	Human	8.1	pIC50	=	8.1	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	616	18	2	4	8.7	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc(F)cc3)cc(-c3ccc(F)cc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099324	9012	0	None	-	1	Human	8.1	pIC50	=	8.1	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	616	18	2	4	8.7	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc(F)cc3)cc(-c3ccc(F)cc3)c2)c1CCC(=O)O	10.1021/jm1001919
	122023	50508	56	None	1	3	Human	7.1	pIC50	=	7.1	Functional	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1021/jm960088k
	CHEMBL15766	50508	56	None	1	3	Human	7.1	pIC50	=	7.1	Functional	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1021/jm960088k
	CHEMBL45460	50508	56	None	1	3	Human	7.1	pIC50	=	7.1	Functional	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1021/jm960088k
	132379	111227	13	None	-	1	Human	8.1	pIC50	=	8.1	Functional	Antagonistic activity against monkey neutrophil LTB4 receptor 2 min after an iv dose of 3 mg/kg. Antagonistic activity against monkey neutrophil LTB4 receptor 2 min after an iv dose of 3 mg/kg.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	CHEMBL328712	111227	13	None	-	1	Human	8.1	pIC50	=	8.1	Functional	Antagonistic activity against monkey neutrophil LTB4 receptor 2 min after an iv dose of 3 mg/kg. Antagonistic activity against monkey neutrophil LTB4 receptor 2 min after an iv dose of 3 mg/kg.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	3368	1146	18	None	3	2	Human	8.0	pIC50	=	8.0	Functional	Tested for antagonistic activity against LTB4 receptor in guinea pig spleen membraneTested for antagonistic activity against LTB4 receptor in guinea pig spleen membrane	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	9867257	1146	18	None	3	2	Human	8.0	pIC50	=	8.0	Functional	Tested for antagonistic activity against LTB4 receptor in guinea pig spleen membraneTested for antagonistic activity against LTB4 receptor in guinea pig spleen membrane	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	CHEMBL51770	1146	18	None	3	2	Human	8.0	pIC50	=	8.0	Functional	Tested for antagonistic activity against LTB4 receptor in guinea pig spleen membraneTested for antagonistic activity against LTB4 receptor in guinea pig spleen membrane	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	10022413	27436	0	None	-	1	Human	6.1	pIC50	=	6.1	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	376	9	2	4	5.0	Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136991	27436	0	None	-	1	Human	6.1	pIC50	=	6.1	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	376	9	2	4	5.0	Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10692884	187572	0	None	-	0	Human	8.0	pKi	=	8.0	Functional	Leukotriene B4 receptor antagonistic activity was measured by the inhibition of LTB4 induced [Ca2+] release from human PMNsLeukotriene B4 receptor antagonistic activity was measured by the inhibition of LTB4 induced [Ca2+] release from human PMNs	ChEMBL	409	10	1	3	5.1	CCN(CC)C(=O)/C=C(\C)c1ccc(OC(C)c2ccccc2)c(CCC(=O)O)c1	10.1021/jm980540v
	CHEMBL49866	187572	0	None	-	0	Human	8.0	pKi	=	8.0	Functional	Leukotriene B4 receptor antagonistic activity was measured by the inhibition of LTB4 induced [Ca2+] release from human PMNsLeukotriene B4 receptor antagonistic activity was measured by the inhibition of LTB4 induced [Ca2+] release from human PMNs	ChEMBL	409	10	1	3	5.1	CCN(CC)C(=O)/C=C(\C)c1ccc(OC(C)c2ccccc2)c(CCC(=O)O)c1	10.1021/jm980540v
	60490	205520	104	None	-8	2	Human	8.2	pIC50	=	8.2	Functional	In vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophilsIn vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophils	Drug Central	236	2	2	3	2.7	CC(c1cc2ccccc2s1)N(O)C(N)=O	None
	CHEMBL93	205520	104	None	-8	2	Human	8.2	pIC50	=	8.2	Functional	In vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophilsIn vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophils	Drug Central	236	2	2	3	2.7	CC(c1cc2ccccc2s1)N(O)C(N)=O	None
	71398	105945	37	None	3	2	Human	8.2	pIC50	=	8.2	Functional	The compound was tested for its inhibitory activity against LTB4 in human PMNThe compound was tested for its inhibitory activity against LTB4 in human PMN	Drug Central	302	5	4	4	3.6	C[C@@H](Cc1ccc(O)c(O)c1)[C@H](C)Cc1ccc(O)c(O)c1	None
	CHEMBL313972	105945	37	None	3	2	Human	8.2	pIC50	=	8.2	Functional	The compound was tested for its inhibitory activity against LTB4 in human PMNThe compound was tested for its inhibitory activity against LTB4 in human PMN	Drug Central	302	5	4	4	3.6	C[C@@H](Cc1ccc(O)c(O)c1)[C@H](C)Cc1ccc(O)c(O)c1	None
	6157	2878	16	None	-	1	Human	5.8	pIC50	=	5.8	Functional	UnclassifiedUnclassified	Guide to Pharmacology	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	1332129
	6438358	2878	16	None	-	1	Human	5.8	pIC50	=	5.8	Functional	UnclassifiedUnclassified	Guide to Pharmacology	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	1332129
	CHEMBL422420	2878	16	None	-	1	Human	5.8	pIC50	=	5.8	Functional	UnclassifiedUnclassified	Guide to Pharmacology	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	1332129
	114999	3469	15	None	-	1	Human	6.1	pIC50	=	6.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	7786309
	6156	3469	15	None	-	1	Human	6.1	pIC50	=	6.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	7786309
	CHEMBL14823	3469	15	None	-	1	Human	6.1	pIC50	=	6.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	7786309
	3368	1146	18	None	3	2	Human	8.1	pIC50	=	8.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	7714764
	9867257	1146	18	None	3	2	Human	8.1	pIC50	=	8.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	7714764
	CHEMBL51770	1146	18	None	3	2	Human	8.1	pIC50	=	8.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	7714764
	25192022	3291	4	None	21	2	Human	8.1	pIC50	=	8.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	20214997
	6158	3291	4	None	21	2	Human	8.1	pIC50	=	8.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	20214997
	CHEMBL1098560	3291	4	None	21	2	Human	8.1	pIC50	=	8.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	20214997
	177941	1551	40	None	-	1	Human	8.4	pIC50	=	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	2948	1551	40	None	-	1	Human	8.4	pIC50	=	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	CHEMBL329123	1551	40	None	-	1	Human	8.4	pIC50	=	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	DB12850	1551	40	None	-	1	Human	8.4	pIC50	=	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	6154	627	0	None	-	1	Human	8.5	pIC50	=	8.5	Functional	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	11259574
	6154	627	0	None	-	1	Human	8.5	pIC50	=	8.5	Functional	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	17170051
	9956189	627	0	None	-	1	Human	8.5	pIC50	=	8.5	Functional	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	11259574
	9956189	627	0	None	-	1	Human	8.5	pIC50	=	8.5	Functional	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	17170051
	6155	1149	0	None	1318	2	Human	8.6	pIC50	=	8.6	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	9823886	1149	0	None	1318	2	Human	8.6	pIC50	=	8.6	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	CHEMBL301829	1149	0	None	1318	2	Human	8.6	pIC50	=	8.6	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	DB13053	1149	0	None	1318	2	Human	8.6	pIC50	=	8.6	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393

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Ligands					Receptor			Assay information							Chemical information
Sel. page	Common name	GPCRdb ID	#Vendors	Reference ligand	Fold selectivity (Affinity)	# tested GPCRs (Affinity)	Species	p-value (-log)	Type	Activity Relation	Activity Value	Assay Type	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI
	44379678	164359	0	None	-	0	Human	10.0	pIC50	=	10	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	527	14	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC(C)C)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL422388	164359	0	None	-	0	Human	10.0	pIC50	=	10	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	527	14	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC(C)C)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	44379453	57764	0	None	-	0	Human	9.8	pIC50	=	9.8	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	513	13	1	6	4.9	CCCc1c(OCCCOc2ccc(C(=O)N(C)C)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL167350	57764	0	None	-	0	Human	9.8	pIC50	=	9.8	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	513	13	1	6	4.9	CCCc1c(OCCCOc2ccc(C(=O)N(C)C)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	15817161	57812	0	None	-	0	Human	9.1	pIC50	=	9.1	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	499	13	2	6	4.6	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL167804	57812	0	None	-	0	Human	9.1	pIC50	=	9.1	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	499	13	2	6	4.6	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	9865985	28446	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	405	9	1	5	5.2	O=C(O)CCCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137759	28446	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	405	9	1	5	5.2	O=C(O)CCCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1	10.1021/jm00101a008
	114999	3469	15	None	-	1	Human	9.0	pIC50	=	9	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/S0960-894X(01)80853-2
	6156	3469	15	None	-	1	Human	9.0	pIC50	=	9	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/S0960-894X(01)80853-2
	CHEMBL14823	3469	15	None	-	1	Human	9.0	pIC50	=	9	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/S0960-894X(01)80853-2
	204058	162895	5	None	-	1	Human	8.9	pIC50	=	8.9	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@H](CCC(=O)O)CC2	10.1021/jm960088k
	CHEMBL419948	162895	5	None	-	1	Human	8.9	pIC50	=	8.9	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@H](CCC(=O)O)CC2	10.1021/jm960088k
	196905	111128	8	None	-	0	Human	8.8	pIC50	=	8.8	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2	10.1021/jm960088k
	CHEMBL328492	111128	8	None	-	0	Human	8.8	pIC50	=	8.8	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2	10.1021/jm960088k
	2487	2326	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	5280492	2326	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL65061	2326	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	DB12961	2326	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	6444688	186727	29	None	-	1	Human	8.7	pIC50	=	8.7	Binding	Inhibition of binding of [3H]LTB4 to receptor on nonradioactive LTB4Inhibition of binding of [3H]LTB4 to receptor on nonradioactive LTB4	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00064a006
	CHEMBL49302	186727	29	None	-	1	Human	8.7	pIC50	=	8.7	Binding	Inhibition of binding of [3H]LTB4 to receptor on nonradioactive LTB4Inhibition of binding of [3H]LTB4 to receptor on nonradioactive LTB4	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00064a006
	2487	2326	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophilsInhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00172a020
	5280492	2326	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophilsInhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00172a020
	CHEMBL65061	2326	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophilsInhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00172a020
	DB12961	2326	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophilsInhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00172a020
	11799000	16971	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Compound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membraneCompound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membrane	ChEMBL	482	9	1	4	5.1	CN(O)C(=O)c1cc(CC(=O)N(C)CCc2ccccc2)c2cccc(OCc3ccccc3)c2c1	10.1021/jm950699x
	CHEMBL125611	16971	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Compound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membraneCompound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membrane	ChEMBL	482	9	1	4	5.1	CN(O)C(=O)c1cc(CC(=O)N(C)CCc2ccccc2)c2cccc(OCc3ccccc3)c2c1	10.1021/jm950699x
	10385899	27185	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	393	9	1	4	5.6	COc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	CHEMBL136805	27185	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	393	9	1	4	5.6	COc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	9999755	26352	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2F)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL136094	26352	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2F)cc(-c2ccccc2)n1	10.1021/jm00101a008
	44357534	26520	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	385	9	0	6	4.7	c1ccc(-c2cc(OCCCCCn3cnnn3)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136243	26520	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	385	9	0	6	4.7	c1ccc(-c2cc(OCCCCCn3cnnn3)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10071290	27875	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137303	27875	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	196905	111128	8	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL328492	111128	8	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	11756030	58437	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	509	13	1	7	5.9	CCCc1c(OCCCOc2ccc(-c3cocn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL168658	58437	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	509	13	1	7	5.9	CCCc1c(OCCCOc2ccc(-c3cocn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	14946858	28933	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	375	9	0	4	5.5	COC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL138174	28933	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	375	9	0	4	5.5	COC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10407251	118563	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	377	8	1	3	5.9	Cc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	CHEMBL342688	118563	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	377	8	1	3	5.9	Cc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	15666577	9096	1	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptors at the concentration of 10e-5 MCapability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptors at the concentration of 10e-5 M	ChEMBL	330	11	1	2	5.5	O=C(O)CCCCCCc1ccsc1CCCc1ccccc1	10.1021/jm00095a011
	CHEMBL110402	9096	1	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptors at the concentration of 10e-5 MCapability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptors at the concentration of 10e-5 M	ChEMBL	330	11	1	2	5.5	O=C(O)CCCCCCc1ccsc1CCCc1ccccc1	10.1021/jm00095a011
	15666579	5536	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	364	11	1	2	6.2	O=C(O)CCCCCCc1ccsc1CCCc1ccc(Cl)cc1	10.1021/jm00095a011
	CHEMBL107760	5536	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	364	11	1	2	6.2	O=C(O)CCCCCCc1ccsc1CCCc1ccc(Cl)cc1	10.1021/jm00095a011
	15666578	7807	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	364	11	1	2	6.2	O=C(O)CCCCCCc1csc(CCCc2ccc(Cl)cc2)c1	10.1021/jm00095a011
	CHEMBL109015	7807	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	364	11	1	2	6.2	O=C(O)CCCCCCc1csc(CCCc2ccc(Cl)cc2)c1	10.1021/jm00095a011
	15666603	8039	1	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	330	11	1	2	5.5	O=C(O)CCCCCCc1sccc1CCCc1ccccc1	10.1021/jm00095a011
	CHEMBL109176	8039	1	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	330	11	1	2	5.5	O=C(O)CCCCCCc1sccc1CCCc1ccccc1	10.1021/jm00095a011
	15666621	9137	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	406	12	1	2	7.2	O=C(O)CCCCCCc1sc(-c2ccccc2)cc1CCCc1ccccc1	10.1021/jm00095a011
	CHEMBL110707	9137	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	406	12	1	2	7.2	O=C(O)CCCCCCc1sc(-c2ccccc2)cc1CCCc1ccccc1	10.1021/jm00095a011
	44315785	14467	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	326	11	3	3	4.1	CCCCCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CC(=O)O)C1	10.1016/0960-894X(96)00424-6
	CHEMBL1205307	14467	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	326	11	3	3	4.1	CCCCCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CC(=O)O)C1	10.1016/0960-894X(96)00424-6
	CHEMBL80541	14467	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	326	11	3	3	4.1	CCCCCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CC(=O)O)C1	10.1016/0960-894X(96)00424-6
	11741184	27936	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	391	10	1	4	5.4	COc1ccc(-c2cc(-c3ccccc3)cc(OCCCCCC(=O)O)n2)cc1	10.1021/jm00101a008
	CHEMBL137342	27936	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	391	10	1	4	5.4	COc1ccc(-c2cc(-c3ccccc3)cc(OCCCCCC(=O)O)n2)cc1	10.1021/jm00101a008
	15666575	5102	1	None	-	0	Human	5.0	pIC50	=	5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	316	10	1	2	5.1	O=C(O)CCCCCCc1csc(CCc2ccccc2)c1	10.1021/jm00095a011
	CHEMBL106055	5102	1	None	-	0	Human	5.0	pIC50	=	5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	316	10	1	2	5.1	O=C(O)CCCCCCc1csc(CCc2ccccc2)c1	10.1021/jm00095a011
	15666597	109137	1	None	-	0	Human	5.0	pIC50	=	5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	302	9	1	2	4.9	O=C(O)CCCCCCc1csc(Cc2ccccc2)c1	10.1021/jm00095a011
	CHEMBL322290	109137	1	None	-	0	Human	5.0	pIC50	=	5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	302	9	1	2	4.9	O=C(O)CCCCCCc1csc(Cc2ccccc2)c1	10.1021/jm00095a011
	135531245	203543	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	398	10	2	7	3.8	CCc1cc(-c2ccnn2C)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1	10.1021/jm00041a021
	CHEMBL78966	203543	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	398	10	2	7	3.8	CCc1cc(-c2ccnn2C)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1	10.1021/jm00041a021
	10046878	28206	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	405	10	1	4	5.7	COc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137531	28206	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	405	10	1	4	5.7	COc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	135503765	203492	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	396	10	3	5	3.8	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1cccc(CC(=O)O)c1	10.1021/jm00041a021
	CHEMBL78605	203492	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	396	10	3	5	3.8	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1cccc(CC(=O)O)c1	10.1021/jm00041a021
	15666618	9149	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	344	11	1	2	5.7	CC(CCCCCc1sccc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	CHEMBL110767	9149	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	344	11	1	2	5.7	CC(CCCCCc1sccc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	10024190	25753	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	404	10	1	4	5.5	CN(C)c1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL135431	25753	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	404	10	1	4	5.5	CN(C)c1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10052488	58727	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	523	13	1	7	6.2	CCCc1c(OCCCOc2ccc(-c3coc(C)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL169446	58727	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	523	13	1	7	6.2	CCCc1c(OCCCOc2ccc(-c3coc(C)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	10069417	164345	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2cccc(Cl)c2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL422282	164345	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2cccc(Cl)c2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	18373405	31467	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	525	7	1	3	7.3	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Br)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL140539	31467	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	525	7	1	3	7.3	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Br)cc12	10.1016/j.bmcl.2003.08.070
	9985159	58799	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	555	14	1	8	6.4	CCCc1c(OCCCOc2ccc(-c3csc(OC)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL169835	58799	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	555	14	1	8	6.4	CCCc1c(OCCCOc2ccc(-c3csc(OC)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	44385218	59344	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	343	5	2	2	4.7	O=C(/C=C/c1ccc(-c2ccccc2)cc1)Nc1cccc(C(=O)O)c1	10.1016/S0960-894X(97)00134-0
	CHEMBL172201	59344	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	343	5	2	2	4.7	O=C(/C=C/c1ccc(-c2ccccc2)cc1)Nc1cccc(C(=O)O)c1	10.1016/S0960-894X(97)00134-0
	44385131	128964	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	373	6	2	3	4.7	COc1cccc(C(=O)O)c1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL367291	128964	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	373	6	2	3	4.7	COc1cccc(C(=O)O)c1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	6444688	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Binding affinity to leukotriene B4 receptor on intact human PMNs by displacing radioligand [3H]LTB4Binding affinity to leukotriene B4 receptor on intact human PMNs by displacing radioligand [3H]LTB4	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00046a017
	CHEMBL49302	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Binding affinity to leukotriene B4 receptor on intact human PMNs by displacing radioligand [3H]LTB4Binding affinity to leukotriene B4 receptor on intact human PMNs by displacing radioligand [3H]LTB4	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00046a017
	18963028	14438	0	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	376	11	2	6	4.2	CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205053	14438	0	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	376	11	2	6	4.2	CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL47716	14438	0	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	376	11	2	6	4.2	CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	10343923	27560	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	453	9	1	5	6.1	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137074	27560	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	453	9	1	5	6.1	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	135401173	104287	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	396	10	3	5	3.8	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1ccccc1CC(=O)O	10.1021/jm00041a021
	CHEMBL310870	104287	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	396	10	3	5	3.8	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1ccccc1CC(=O)O	10.1021/jm00041a021
	6444688	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00070a015
	CHEMBL49302	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00070a015
	10053662	59333	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	565	15	1	7	7.1	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2	10.1021/jm00006a002
	CHEMBL172168	59333	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	565	15	1	7	7.1	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2	10.1021/jm00006a002
	44337707	109241	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	434	12	1	2	7.8	CC(C)(CCCCCc1cc(-c2ccccc2)sc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	CHEMBL322985	109241	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	434	12	1	2	7.8	CC(C)(CCCCCc1cc(-c2ccccc2)sc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	9980059	28132	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccc(C(F)(F)F)cc2)n1	10.1021/jm00101a008
	CHEMBL137480	28132	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccc(C(F)(F)F)cc2)n1	10.1021/jm00101a008
	44385159	61007	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.0	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)c(C)c1	10.1016/S0960-894X(97)00134-0
	CHEMBL176747	61007	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.0	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)c(C)c1	10.1016/S0960-894X(97)00134-0
	6444688	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	CHEMBL49302	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	10091738	27580	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	389	9	1	3	6.0	Cc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137089	27580	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	389	9	1	3	6.0	Cc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	6444688	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Inhibition of specific binding of [3H]LTB4 ( 0.1 nM) to LTB4 receptor on intact human neutrophilsInhibition of specific binding of [3H]LTB4 ( 0.1 nM) to LTB4 receptor on intact human neutrophils	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00064a006
	CHEMBL49302	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Inhibition of specific binding of [3H]LTB4 ( 0.1 nM) to LTB4 receptor on intact human neutrophilsInhibition of specific binding of [3H]LTB4 ( 0.1 nM) to LTB4 receptor on intact human neutrophils	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00064a006
	6444688	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophilsInhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophils	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00172a020
	CHEMBL49302	186727	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophilsInhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophils	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00172a020
	6435820	164453	6	None	-	1	Human	6.9	pIC50	=	6.9	Binding	Inhibitory concentration against LTB4 receptors in human PMNsInhibitory concentration against LTB4 receptors in human PMNs	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00070a015
	CHEMBL422598	164453	6	None	-	1	Human	6.9	pIC50	=	6.9	Binding	Inhibitory concentration against LTB4 receptors in human PMNsInhibitory concentration against LTB4 receptors in human PMNs	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00070a015
	204058	162895	5	None	-	1	Human	7.8	pIC50	=	7.8	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@H](CCC(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL419948	162895	5	None	-	1	Human	7.8	pIC50	=	7.8	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@H](CCC(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	9805394	57264	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	485	13	2	6	4.3	CCCc1c(OCCCOc2ccc(C(N)=O)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL166699	57264	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	485	13	2	6	4.3	CCCc1c(OCCCOc2ccc(C(N)=O)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	10385899	27185	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	393	9	1	4	5.6	COc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	CHEMBL136805	27185	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	393	9	1	4	5.6	COc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	10474602	25759	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	375	10	1	3	5.8	O=C(O)CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL135434	25759	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	375	10	1	3	5.8	O=C(O)CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10069416	28158	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL137497	28158	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	10341135	29160	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	403	10	1	3	6.5	CC(C)(CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL138380	29160	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	403	10	1	3	6.5	CC(C)(CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	44381856	167980	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	509	13	1	7	6.1	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC2C(=O)O	10.1021/jm00006a002
	CHEMBL435665	167980	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	509	13	1	7	6.1	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC2C(=O)O	10.1021/jm00006a002
	9930128	60082	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.1	COc1ccc(C(=O)O)cc1NC(=O)/C=C(\C)c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL175073	60082	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.1	COc1ccc(C(=O)O)cc1NC(=O)/C=C(\C)c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	11726048	27376	1	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	360	9	1	3	4.8	NC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL136953	27376	1	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	360	9	1	3	4.8	NC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10071290	27875	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137303	27875	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10318241	28121	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	390	10	2	4	5.5	CNc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137472	28121	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	390	10	2	4	5.5	CNc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10250881	24851	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	408	9	1	5	5.5	CC(C)(CCCCOc1cc(-c2ccc([N+](=O)[O-])cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL134698	24851	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	408	9	1	5	5.5	CC(C)(CCCCOc1cc(-c2ccc([N+](=O)[O-])cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	10390056	116036	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	472	10	2	4	5.9	O=C(O)CCCCCOc1cc(-c2ccc(NC(=O)C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL336303	116036	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	472	10	2	4	5.9	O=C(O)CCCCCOc1cc(-c2ccc(NC(=O)C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10451768	27673	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	369	8	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1	10.1021/jm00101a007
	CHEMBL137168	27673	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	369	8	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1	10.1021/jm00101a007
	15666613	9138	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	344	11	1	2	5.8	Cc1cc(CCCc2ccccc2)c(CCCCCCC(=O)O)s1	10.1021/jm00095a011
	CHEMBL110708	9138	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	344	11	1	2	5.8	Cc1cc(CCCc2ccccc2)c(CCCCCCC(=O)O)s1	10.1021/jm00095a011
	44385199	59316	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	375	7	2	3	4.6	COc1ccc(C(=O)O)cc1NC(=O)CCc1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL172091	59316	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	375	7	2	3	4.6	COc1ccc(C(=O)O)cc1NC(=O)CCc1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	20704716	184132	0	None	-	1	Human	4.8	pIC50	=	4.8	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	488	5	1	9	2.4	CN1C(=N)N(C)/C(=N/c2nc(Cc3ccc4c(c3)OCO4)c(Cc3ccc4c(c3)OCO4)n2C)C1=O	10.1021/np50100a005
	CHEMBL485054	184132	0	None	-	1	Human	4.8	pIC50	=	4.8	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	488	5	1	9	2.4	CN1C(=N)N(C)/C(=N/c2nc(Cc3ccc4c(c3)OCO4)c(Cc3ccc4c(c3)OCO4)n2C)C1=O	10.1021/np50100a005
	11549986	155654	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	1542	48	11	26	1.8	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)c1ccc(N/N=C/c2ccccc2)nc1	10.1021/jm050383h
	CHEMBL406432	155654	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	1542	48	11	26	1.8	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)c1ccc(N/N=C/c2ccccc2)nc1	10.1021/jm050383h
	44386172	165226	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	397	6	2	5	4.2	COc1ccc(-c2nn[nH]n2)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL424779	165226	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	397	6	2	5	4.2	COc1ccc(-c2nn[nH]n2)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	11726048	27376	1	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	360	9	1	3	4.8	NC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL136953	27376	1	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	360	9	1	3	4.8	NC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	44359651	118665	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	481	7	1	3	7.2	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Cl)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL343124	118665	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	481	7	1	3	7.2	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Cl)cc12	10.1016/j.bmcl.2003.08.070
	6441619	205045	13	None	-	1	Human	4.8	pIC50	=	4.8	Binding	Inhibitory concentration LTB4 with [3H]LTD4 in LTD4 receptor binding assayInhibitory concentration LTB4 with [3H]LTD4 in LTD4 receptor binding assay	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960248s
	CHEMBL90214	205045	13	None	-	1	Human	4.8	pIC50	=	4.8	Binding	Inhibitory concentration LTB4 with [3H]LTD4 in LTD4 receptor binding assayInhibitory concentration LTB4 with [3H]LTD4 in LTD4 receptor binding assay	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960248s
	15718079	100954	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1cc2oc3c(C(=O)O)cccc3c(=O)c2cc1CCC(=O)O	10.1021/jm00064a006
	CHEMBL297501	100954	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1cc2oc3c(C(=O)O)cccc3c(=O)c2cc1CCC(=O)O	10.1021/jm00064a006
	10430674	118820	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	393	9	1	3	5.8	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2F)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL344230	118820	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	393	9	1	3	5.8	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2F)n1)C(=O)O	10.1021/jm00101a008
	10315808	26728	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	349	9	1	3	5.3	O=C(O)CCCCCCOc1cc(-c2ccccc2)c2ccccc2n1	10.1021/jm00101a007
	CHEMBL136433	26728	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	349	9	1	3	5.3	O=C(O)CCCCCCOc1cc(-c2ccccc2)c2ccccc2n1	10.1021/jm00101a007
	10248148	115482	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	363	8	1	3	5.6	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL335525	115482	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	363	8	1	3	5.6	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	15839736	14456	0	None	-	1	Human	6.7	pIC50	=	6.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	476	9	2	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1	10.1016/S0960-894X(01)80999-9
	CHEMBL1205143	14456	0	None	-	1	Human	6.7	pIC50	=	6.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	476	9	2	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1	10.1016/S0960-894X(01)80999-9
	CHEMBL58534	14456	0	None	-	1	Human	6.7	pIC50	=	6.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	476	9	2	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1	10.1016/S0960-894X(01)80999-9
	44385258	60034	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	7	2	3	5.1	CCOc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL174638	60034	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	7	2	3	5.1	CCOc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	6444688	186727	29	None	-	1	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a007
	CHEMBL49302	186727	29	None	-	1	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a007
	10022413	27436	0	None	-	0	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	376	9	2	4	5.0	Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136991	27436	0	None	-	0	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	376	9	2	4	5.0	Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10343923	27560	0	None	-	0	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	453	9	1	5	6.1	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137074	27560	0	None	-	0	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	453	9	1	5	6.1	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	10341242	27927	0	None	-	0	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	405	10	1	4	5.7	COc1cccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)c1	10.1021/jm00101a008
	CHEMBL137336	27927	0	None	-	0	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	405	10	1	4	5.7	COc1cccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)c1	10.1021/jm00101a008
	6444688	186727	29	None	-	1	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a008
	CHEMBL49302	186727	29	None	-	1	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a008
	9805394	57264	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	485	13	2	6	4.3	CCCc1c(OCCCOc2ccc(C(N)=O)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL166699	57264	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	485	13	2	6	4.3	CCCc1c(OCCCOc2ccc(C(N)=O)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	18963032	100610	0	None	-	1	Human	8.5	pIC50	=	8.5	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	444	11	2	6	4.5	CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	CHEMBL294987	100610	0	None	-	1	Human	8.5	pIC50	=	8.5	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	444	11	2	6	4.5	CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	114999	3469	15	None	-	1	Human	7.7	pIC50	=	7.7	Binding	Compound was tested for inhibitory activity against LTB4 (leukotriene) bindingCompound was tested for inhibitory activity against LTB4 (leukotriene) binding	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm960088k
	6156	3469	15	None	-	1	Human	7.7	pIC50	=	7.7	Binding	Compound was tested for inhibitory activity against LTB4 (leukotriene) bindingCompound was tested for inhibitory activity against LTB4 (leukotriene) binding	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm960088k
	CHEMBL14823	3469	15	None	-	1	Human	7.7	pIC50	=	7.7	Binding	Compound was tested for inhibitory activity against LTB4 (leukotriene) bindingCompound was tested for inhibitory activity against LTB4 (leukotriene) binding	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm960088k
	10477988	27917	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	433	9	1	5	5.8	CC(C)(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137330	27917	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	433	9	1	5	5.8	CC(C)(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	44357546	116240	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	399	9	0	6	5.2	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)n1cnnn1	10.1021/jm00101a008
	CHEMBL337563	116240	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	399	9	0	6	5.2	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)n1cnnn1	10.1021/jm00101a008
	178581	139711	1	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 hr at 37 degree CInhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C	ChEMBL	413	9	1	5	5.5	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnn[nH]1	10.1021/jm050383h
	CHEMBL380555	139711	1	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 hr at 37 degree CInhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C	ChEMBL	413	9	1	5	5.5	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnn[nH]1	10.1021/jm050383h
	15666615	9072	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Capability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	372	11	1	2	6.4	Cc1cc(CCCc2ccccc2)c(CCCCCC(C)(C)C(=O)O)s1	10.1021/jm00095a011
	CHEMBL110243	9072	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Capability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	372	11	1	2	6.4	Cc1cc(CCCc2ccccc2)c(CCCCCC(C)(C)C(=O)O)s1	10.1021/jm00095a011
	10386030	118753	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	395	9	1	3	6.1	O=C(O)CCCCCOc1cc(-c2ccccc2Cl)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL343710	118753	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	395	9	1	3	6.1	O=C(O)CCCCCOc1cc(-c2ccccc2Cl)cc(-c2ccccc2)n1	10.1021/jm00101a008
	44379592	56848	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	387	10	3	4	4.7	[N-]=[N+]=Nc1ccc(CCCCC(O)/C=C/C2CCCC(O)(CC(=O)O)C2)cc1	10.1016/s0960-894x(00)00103-7
	CHEMBL164721	56848	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	387	10	3	4	4.7	[N-]=[N+]=Nc1ccc(CCCCC(O)/C=C/C2CCCC(O)(CC(=O)O)C2)cc1	10.1016/s0960-894x(00)00103-7
	44379573	57779	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	414	10	2	4	4.7	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccc(N=[N+]=[N-])cc2)C1	10.1016/s0960-894x(00)00103-7
	CHEMBL167465	57779	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	414	10	2	4	4.7	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccc(N=[N+]=[N-])cc2)C1	10.1016/s0960-894x(00)00103-7
	10021622	28373	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	363	10	1	3	5.7	O=C(O)CCCCCCCOc1cc(-c2ccccc2)c2ccccc2n1	10.1021/jm00101a007
	CHEMBL137676	28373	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	363	10	1	3	5.7	O=C(O)CCCCCCCOc1cc(-c2ccccc2)c2ccccc2n1	10.1021/jm00101a007
	10430946	114980	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccc(Cl)cc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL335142	114980	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccc(Cl)cc2n1)C(=O)O	10.1021/jm00101a007
	15718082	186580	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1ccc2c(=O)c3cccc(C(=O)O)c3oc2c1CCC(=O)O	10.1021/jm00064a006
	CHEMBL49209	186580	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1ccc2c(=O)c3cccc(C(=O)O)c3oc2c1CCC(=O)O	10.1021/jm00064a006
	195214	183247	14	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	454	16	2	4	6.2	CCCCCCCCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1021/jm00064a006
	CHEMBL48068	183247	14	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	454	16	2	4	6.2	CCCCCCCCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1021/jm00064a006
	443292	4941	11	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsTested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophils	ChEMBL	299	3	2	5	3.6	CNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1	10.1021/jm00045a011
	CHEMBL105139	4941	11	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsTested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophils	ChEMBL	299	3	2	5	3.6	CNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1	10.1021/jm00045a011
	9934500	165038	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	472	7	1	4	6.4	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C#N)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL424290	165038	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	472	7	1	4	6.4	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C#N)cc12	10.1016/j.bmcl.2003.08.070
	10319829	25898	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	417	11	1	3	6.9	CC(C)(CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL135612	25898	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	417	11	1	3	6.9	CC(C)(CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10387303	27378	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	418	11	2	4	6.3	CC(C)Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136955	27378	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	418	11	2	4	6.3	CC(C)Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	15839732	45416	0	None	-	1	Human	7.6	pIC50	=	7.6	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	444	13	2	6	4.8	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(C)C(=O)O	10.1016/S0960-894X(00)80304-2
	CHEMBL15299	45416	0	None	-	1	Human	7.6	pIC50	=	7.6	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	444	13	2	6	4.8	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(C)C(=O)O	10.1016/S0960-894X(00)80304-2
	44404447	168182	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	2973	97	22	50	0.7	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](NC(=O)c1ccc(N/N=C/c2ccccc2)nc1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	CHEMBL437275	168182	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	2973	97	22	50	0.7	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](NC(=O)c1ccc(N/N=C/c2ccccc2)nc1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	10007005	120267	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	523	13	1	7	6.1	C=CCc1c(OCCCOc2ccc3c(c2CCC)OC(C(=O)O)CC3)ccc(-c2cscn2)c1OC	10.1021/jm00006a002
	CHEMBL355503	120267	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	523	13	1	7	6.1	C=CCc1c(OCCCOc2ccc3c(c2CCC)OC(C(=O)O)CC3)ccc(-c2cscn2)c1OC	10.1021/jm00006a002
	10474602	25759	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	10	1	3	5.8	O=C(O)CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL135434	25759	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	10	1	3	5.8	O=C(O)CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	9999718	24847	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	378	8	2	4	5.1	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL134697	24847	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	378	8	2	4	5.1	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	10046386	28348	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2ccccc2)c2cc(Cl)ccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL137654	28348	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2ccccc2)c2cc(Cl)ccc2n1)C(=O)O	10.1021/jm00101a007
	10482767	168036	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	553	15	1	7	7.1	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CCC)ccc2c1OC(CCC(=O)O)CC2	10.1021/jm00006a002
	CHEMBL436047	168036	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	553	15	1	7	7.1	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CCC)ccc2c1OC(CCC(=O)O)CC2	10.1021/jm00006a002
	44384958	59551	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.0	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccc(C)cc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL172974	59551	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.0	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccc(C)cc2)cc1	10.1016/S0960-894X(97)00134-0
	135507252	203875	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	438	13	3	5	5.0	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCOc1ccc(CCC(=O)O)cc1	10.1021/jm00041a021
	CHEMBL81503	203875	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	438	13	3	5	5.0	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCOc1ccc(CCC(=O)O)cc1	10.1021/jm00041a021
	10483151	59244	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	571	14	1	8	7.1	CCCc1c(OCCCOc2ccc(-c3csc(SC)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL171780	59244	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	571	14	1	8	7.1	CCCc1c(OCCCOc2ccc(-c3csc(SC)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	18373300	118807	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	492	8	1	5	6.5	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc([N+](=O)[O-])cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL344176	118807	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	492	8	1	5	6.5	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc([N+](=O)[O-])cc12	10.1016/j.bmcl.2003.08.070
	10406292	28169	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	361	9	1	3	5.4	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137504	28169	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	361	9	1	3	5.4	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	204055	206560	5	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	537	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL99099	206560	5	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	537	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	6444688	186727	29	None	-	1	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a008
	CHEMBL49302	186727	29	None	-	1	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a008
	6444688	186727	29	None	-	1	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a007
	CHEMBL49302	186727	29	None	-	1	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a007
	10023244	25942	1	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	389	9	1	3	6.1	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL135671	25942	1	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	389	9	1	3	6.1	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	9999755	26352	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2F)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL136094	26352	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2F)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10091738	27580	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	389	9	1	3	6.0	Cc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137089	27580	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	389	9	1	3	6.0	Cc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10475503	27784	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	390	9	2	4	5.3	CC(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137247	27784	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	390	9	2	4	5.3	CC(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10406292	28169	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	361	9	1	3	5.4	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137504	28169	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	361	9	1	3	5.4	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	9976757	28274	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	375	9	1	3	5.7	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137581	28274	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	375	9	1	3	5.7	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10362331	28497	4	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccc(F)cc2)n1	10.1021/jm00101a008
	CHEMBL137801	28497	4	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccc(F)cc2)n1	10.1021/jm00101a008
	10451768	27673	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	369	8	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1	10.1021/jm00101a007
	CHEMBL137168	27673	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	369	8	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1	10.1021/jm00101a007
	10387480	27788	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	421	8	1	5	5.6	CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)c1nnn[nH]1	10.1021/jm00101a007
	CHEMBL137248	27788	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	421	8	1	5	5.6	CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)c1nnn[nH]1	10.1021/jm00101a007
	10407251	118563	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	377	8	1	3	5.9	Cc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	CHEMBL342688	118563	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	377	8	1	3	5.9	Cc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	10024190	25753	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	404	10	1	4	5.5	CN(C)c1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL135431	25753	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	404	10	1	4	5.5	CN(C)c1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10362331	28497	4	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccc(F)cc2)n1	10.1021/jm00101a008
	CHEMBL137801	28497	4	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccc(F)cc2)n1	10.1021/jm00101a008
	44403823	161384	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	3125	109	25	54	-4.2	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](NC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	CHEMBL415548	161384	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	3125	109	25	54	-4.2	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](NC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	129065	107046	22	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsTested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophils	ChEMBL	377	4	3	6	3.2	Cc1c(O)c(C)c2sc(NCc3ccc(S(N)(=O)=O)cc3)nc2c1C	10.1021/jm00045a011
	CHEMBL318809	107046	22	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsTested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophils	ChEMBL	377	4	3	6	3.2	Cc1c(O)c(C)c2sc(NCc3ccc(S(N)(=O)=O)cc3)nc2c1C	10.1021/jm00045a011
	18963030	14439	0	None	-	1	Human	7.5	pIC50	=	7.5	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	442	12	2	6	5.1	CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205054	14439	0	None	-	1	Human	7.5	pIC50	=	7.5	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	442	12	2	6	5.1	CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL47725	14439	0	None	-	1	Human	7.5	pIC50	=	7.5	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	442	12	2	6	5.1	CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	15666588	96415	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	358	11	1	2	6.1	Cc1cc(CCCCCC(C)C(=O)O)c(CCCc2ccccc2)s1	10.1021/jm00095a011
	CHEMBL265563	96415	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	358	11	1	2	6.1	Cc1cc(CCCCCC(C)C(=O)O)c(CCCc2ccccc2)s1	10.1021/jm00095a011
	15666614	110802	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	358	11	1	2	6.1	Cc1cc(CCCc2ccccc2)c(CCCCCC(C)C(=O)O)s1	10.1021/jm00095a011
	CHEMBL326650	110802	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	358	11	1	2	6.1	Cc1cc(CCCc2ccccc2)c(CCCCCC(C)C(=O)O)s1	10.1021/jm00095a011
	9841175	14465	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	CHEMBL1205297	14465	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	CHEMBL77513	14465	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	114999	3469	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Compound was evaluated in a human neutrophil leukotriene B4 receptor binding assayCompound was evaluated in a human neutrophil leukotriene B4 receptor binding assay	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00126a001
	6156	3469	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Compound was evaluated in a human neutrophil leukotriene B4 receptor binding assayCompound was evaluated in a human neutrophil leukotriene B4 receptor binding assay	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00126a001
	CHEMBL14823	3469	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Compound was evaluated in a human neutrophil leukotriene B4 receptor binding assayCompound was evaluated in a human neutrophil leukotriene B4 receptor binding assay	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00126a001
	44213761	120208	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	346	9	3	3	3.7	O=C(O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccccc2)C1	10.1016/s0960-894x(00)00103-7
	CHEMBL354872	120208	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	346	9	3	3	3.7	O=C(O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccccc2)C1	10.1016/s0960-894x(00)00103-7
	114999	3469	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Concentration inhibiting the binding of [3H]LTB4 to human neutrophilsConcentration inhibiting the binding of [3H]LTB4 to human neutrophils	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00100a034
	6156	3469	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Concentration inhibiting the binding of [3H]LTB4 to human neutrophilsConcentration inhibiting the binding of [3H]LTB4 to human neutrophils	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00100a034
	CHEMBL14823	3469	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Concentration inhibiting the binding of [3H]LTB4 to human neutrophilsConcentration inhibiting the binding of [3H]LTB4 to human neutrophils	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00100a034
	10387303	27378	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	418	11	2	4	6.3	CC(C)Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136955	27378	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	418	11	2	4	6.3	CC(C)Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10427789	27717	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	347	8	1	3	5.0	O=C(O)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137201	27717	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	347	8	1	3	5.0	O=C(O)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10455429	28734	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	431	8	1	3	6.6	CC(C)(CCCCOc1cc(-c2ccc(C(F)(F)F)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL138018	28734	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	431	8	1	3	6.6	CC(C)(CCCCOc1cc(-c2ccc(C(F)(F)F)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	10430678	167834	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	393	9	1	4	5.6	COc1cccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)c1	10.1021/jm00101a007
	CHEMBL434810	167834	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	393	9	1	4	5.6	COc1cccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)c1	10.1021/jm00101a007
	10314767	28315	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	333	7	1	3	4.7	O=C(O)CCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137633	28315	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	333	7	1	3	4.7	O=C(O)CCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10407131	161395	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	9	1	3	5.7	Cc1ccc(-c2cc(-c3ccccc3)cc(OCCCCCC(=O)O)n2)cc1	10.1021/jm00101a008
	CHEMBL415687	161395	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	9	1	3	5.7	Cc1ccc(-c2cc(-c3ccccc3)cc(OCCCCCC(=O)O)n2)cc1	10.1021/jm00101a008
	114999	3469	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00070a015
	6156	3469	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00070a015
	CHEMBL14823	3469	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00070a015
	15666630	7990	0	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	362	11	1	3	6.0	Cc1cc(CCCc2ccccc2)c(SCCCCCC(=O)O)s1	10.1021/jm00095a011
	CHEMBL109129	7990	0	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	362	11	1	3	6.0	Cc1cc(CCCc2ccccc2)c(SCCCCCC(=O)O)s1	10.1021/jm00095a011
	15666582	110184	0	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	360	12	1	3	5.5	COc1ccc(CCCc2sccc2CCCCCCC(=O)O)cc1	10.1021/jm00095a011
	CHEMBL326000	110184	0	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	360	12	1	3	5.5	COc1ccc(CCCc2sccc2CCCCCCC(=O)O)cc1	10.1021/jm00095a011
	44317392	203526	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	511	13	2	7	4.8	CCCc1c(OCCCOc2cc(O)c(C(=O)/C=C/N(C)C)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00041a021
	CHEMBL78859	203526	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	511	13	2	7	4.8	CCCc1c(OCCCOc2cc(O)c(C(=O)/C=C/N(C)C)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00041a021
	2487	2326	32	None	31	2	Human	7.5	pIC50	=	7.5	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80853-2
	5280492	2326	32	None	31	2	Human	7.5	pIC50	=	7.5	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80853-2
	CHEMBL65061	2326	32	None	31	2	Human	7.5	pIC50	=	7.5	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80853-2
	DB12961	2326	32	None	31	2	Human	7.5	pIC50	=	7.5	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80853-2
	114999	3469	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00006a002
	6156	3469	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00006a002
	CHEMBL14823	3469	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00006a002
	10053028	58682	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	540	13	2	8	5.9	CCCc1c(OCCCOc2ccc(-c3csc(N)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL169120	58682	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	540	13	2	8	5.9	CCCc1c(OCCCOc2ccc(-c3csc(N)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	6441619	205045	13	None	-	1	Human	5.5	pIC50	=	5.5	Binding	Inhibitory concentration against LTB4 with [3H]- fMLP in receptor binding assayInhibitory concentration against LTB4 with [3H]- fMLP in receptor binding assay	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960248s
	CHEMBL90214	205045	13	None	-	1	Human	5.5	pIC50	=	5.5	Binding	Inhibitory concentration against LTB4 with [3H]- fMLP in receptor binding assayInhibitory concentration against LTB4 with [3H]- fMLP in receptor binding assay	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960248s
	18963062	14598	0	None	-	1	Human	7.5	pIC50	=	7.5	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	404	13	2	6	4.8	CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1206683	14598	0	None	-	1	Human	7.5	pIC50	=	7.5	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	404	13	2	6	4.8	CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL295799	14598	0	None	-	1	Human	7.5	pIC50	=	7.5	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	404	13	2	6	4.8	CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	15666601	6054	1	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	302	9	1	2	4.7	O=C(O)CCCCc1sccc1CCCc1ccccc1	10.1021/jm00095a011
	CHEMBL108094	6054	1	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	302	9	1	2	4.7	O=C(O)CCCCc1sccc1CCCc1ccccc1	10.1021/jm00095a011
	15839733	45365	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	458	14	2	6	5.2	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(CC)C(=O)O	10.1016/S0960-894X(00)80304-2
	CHEMBL15295	45365	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	458	14	2	6	5.2	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(CC)C(=O)O	10.1016/S0960-894X(00)80304-2
	44296838	193162	0	None	-	0	Human	5.4	pIC50	=	5.4	Binding	Compound was tested for its antagonist activity in a LTB4 human neutrophil receptor binding assay using the natural ligand itselfCompound was tested for its antagonist activity in a LTB4 human neutrophil receptor binding assay using the natural ligand itself	ChEMBL	334	14	2	2	5.4	CCCCC/C=C\C[C@@H](C)/C=C/C=C/C=C/[C@@H](O)CCCC(=O)O	10.1016/S0960-894X(01)80795-2
	CHEMBL53967	193162	0	None	-	0	Human	5.4	pIC50	=	5.4	Binding	Compound was tested for its antagonist activity in a LTB4 human neutrophil receptor binding assay using the natural ligand itselfCompound was tested for its antagonist activity in a LTB4 human neutrophil receptor binding assay using the natural ligand itself	ChEMBL	334	14	2	2	5.4	CCCCC/C=C\C[C@@H](C)/C=C/C=C/C=C/[C@@H](O)CCCC(=O)O	10.1016/S0960-894X(01)80795-2
	15839729	205151	1	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm960088k
	CHEMBL15559	205151	1	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm960088k
	CHEMBL90788	205151	1	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm960088k
	15839729	205151	1	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	CHEMBL15559	205151	1	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	CHEMBL90788	205151	1	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	9955657	204919	11	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingCompound was tested for inhibitory activity against Leukotriene B4 receptor binding	ChEMBL	455	13	2	5	4.9	COc1cc(C(=O)N(C(C)C)C(C)C)ccc1OCCCCCOc1ccc(C(=N)N)cc1	10.1021/jm960088k
	CHEMBL89326	204919	11	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingCompound was tested for inhibitory activity against Leukotriene B4 receptor binding	ChEMBL	455	13	2	5	4.9	COc1cc(C(=O)N(C(C)C)C(C)C)ccc1OCCCCCOc1ccc(C(=N)N)cc1	10.1021/jm960088k
	9893718	204765	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm960088k
	CHEMBL292768	204765	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm960088k
	CHEMBL88337	204765	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm960088k
	9893718	204765	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL292768	204765	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL88337	204765	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	10046878	28206	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	405	10	1	4	5.7	COc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137531	28206	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	405	10	1	4	5.7	COc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	9976757	28274	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	9	1	3	5.7	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137581	28274	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	9	1	3	5.7	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10430674	118820	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	393	9	1	3	5.8	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2F)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL344230	118820	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	393	9	1	3	5.8	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2F)n1)C(=O)O	10.1021/jm00101a008
	9912012	161643	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	458	12	2	6	4.9	CCCc1c(OCCCOc2cc(O)c(OCC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	CHEMBL416277	161643	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	458	12	2	6	4.9	CCCc1c(OCCCOc2cc(O)c(OCC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	10364772	27934	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	419	9	1	5	5.4	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137341	27934	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	419	9	1	5	5.4	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	204055	206560	5	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	537	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL99099	206560	5	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	537	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	135543808	203862	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	480	11	3	6	4.9	CCCc1c(OCCCOc2cc(O)c(-c3cc[nH]n3)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00041a021
	CHEMBL81401	203862	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	480	11	3	6	4.9	CCCc1c(OCCCOc2cc(O)c(-c3cc[nH]n3)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00041a021
	132379	111227	13	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsCompound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cells	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm9506985
	CHEMBL328712	111227	13	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsCompound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cells	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm9506985
	132379	111227	13	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Concentration inhibiting the binding of [3H]LTB4 to human whole cell neutrophilsConcentration inhibiting the binding of [3H]LTB4 to human whole cell neutrophils	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	CHEMBL328712	111227	13	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Concentration inhibiting the binding of [3H]LTB4 to human whole cell neutrophilsConcentration inhibiting the binding of [3H]LTB4 to human whole cell neutrophils	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	10292143	116084	1	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL336665	116084	1	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL48667	116084	1	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	10292143	116084	1	None	-	1	Human	8.3	pIC50	=	8.3	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80454-0
	CHEMBL336665	116084	1	None	-	1	Human	8.3	pIC50	=	8.3	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80454-0
	CHEMBL48667	116084	1	None	-	1	Human	8.3	pIC50	=	8.3	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80454-0
	10090758	58676	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	373	9	2	3	3.7	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccccc2)C1	10.1016/s0960-894x(00)00103-7
	CHEMBL169055	58676	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	373	9	2	3	3.7	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccccc2)C1	10.1016/s0960-894x(00)00103-7
	10047140	27385	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2cccc(Cl)c2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL136960	27385	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2cccc(Cl)c2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10001576	28154	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccc(Cl)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137494	28154	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccc(Cl)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	9999718	24847	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	378	8	2	4	5.1	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL134697	24847	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	378	8	2	4	5.1	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	14946858	28933	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	9	0	4	5.5	COC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL138174	28933	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	9	0	4	5.5	COC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10068808	27487	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	387	8	1	5	4.9	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)c1nnn[nH]1	10.1021/jm00101a007
	CHEMBL137030	27487	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	387	8	1	5	4.9	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)c1nnn[nH]1	10.1021/jm00101a007
	18373405	31467	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	525	7	1	3	7.3	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Br)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL140539	31467	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	525	7	1	3	7.3	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Br)cc12	10.1016/j.bmcl.2003.08.070
	18373357	116280	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	461	7	1	3	6.9	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL337790	116280	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	461	7	1	3	6.9	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C)cc12	10.1016/j.bmcl.2003.08.070
	44359651	118665	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	481	7	1	3	7.2	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Cl)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL343124	118665	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	481	7	1	3	7.2	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Cl)cc12	10.1016/j.bmcl.2003.08.070
	10021742	9350	4	None	-	1	Human	5.4	pIC50	=	5.4	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	CHEMBL111825	9350	4	None	-	1	Human	5.4	pIC50	=	5.4	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	10248148	115482	0	None	-	0	Human	5.4	pIC50	=	5.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	363	8	1	3	5.6	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL335525	115482	0	None	-	0	Human	5.4	pIC50	=	5.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	363	8	1	3	5.6	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	44270188	51096	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	484	13	1	6	5.4	CCCc1cc(OCCCOc2ccc(C(C)=O)c(OC)c2CCC)cc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	CHEMBL15817	51096	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	484	13	1	6	5.4	CCCc1cc(OCCCOc2ccc(C(C)=O)c(OC)c2CCC)cc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	18963059	14440	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	402	11	2	6	4.7	CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205055	14440	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	402	11	2	6	4.7	CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL47726	14440	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	402	11	2	6	4.7	CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	204055	206560	5	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	537	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL99099	206560	5	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	537	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	60490	205520	104	None	-	0	Human	6.4	pIC50	=	6.4	Binding	In vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophilsIn vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophils	ChEMBL	236	2	2	3	2.7	CC(c1cc2ccccc2s1)N(O)C(N)=O	10.1021/jm950725r
	CHEMBL93	205520	104	None	-	0	Human	6.4	pIC50	=	6.4	Binding	In vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophilsIn vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophils	ChEMBL	236	2	2	3	2.7	CC(c1cc2ccccc2s1)N(O)C(N)=O	10.1021/jm950725r
	114999	3469	15	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. (Experiment conducted in the absence of NDGA)Binding affinity towards Leukotriene B4 (LTB4) Receptor. (Experiment conducted in the absence of NDGA)	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00006a002
	6156	3469	15	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. (Experiment conducted in the absence of NDGA)Binding affinity towards Leukotriene B4 (LTB4) Receptor. (Experiment conducted in the absence of NDGA)	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00006a002
	CHEMBL14823	3469	15	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. (Experiment conducted in the absence of NDGA)Binding affinity towards Leukotriene B4 (LTB4) Receptor. (Experiment conducted in the absence of NDGA)	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00006a002
	9934323	99776	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00064a006
	CHEMBL288758	99776	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00064a006
	10170399	14638	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	1018	33	4	16	7.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)c1ccc(N/N=C/c2ccccc2S(=O)(=O)O)nc1	10.1021/jm050383h
	CHEMBL1207275	14638	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	1018	33	4	16	7.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)c1ccc(N/N=C/c2ccccc2S(=O)(=O)O)nc1	10.1021/jm050383h
	CHEMBL384950	14638	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	1018	33	4	16	7.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)c1ccc(N/N=C/c2ccccc2S(=O)(=O)O)nc1	10.1021/jm050383h
	10415107	14714	0	None	-	0	Human	4.4	pIC50	=	4.4	Binding	Displacement of [3H]LTB4 from LTB4 receptor in human neutrophilsDisplacement of [3H]LTB4 from LTB4 receptor in human neutrophils	ChEMBL	504	4	2	7	4.1	CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@]1(C)OCc3c(OS(=O)(=O)O)ccc(OS(=O)(=O)O)c3C[C@H]21	10.1021/np50120a024
	CHEMBL1207951	14714	0	None	-	0	Human	4.4	pIC50	=	4.4	Binding	Displacement of [3H]LTB4 from LTB4 receptor in human neutrophilsDisplacement of [3H]LTB4 from LTB4 receptor in human neutrophils	ChEMBL	504	4	2	7	4.1	CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@]1(C)OCc3c(OS(=O)(=O)O)ccc(OS(=O)(=O)O)c3C[C@H]21	10.1021/np50120a024
	CHEMBL462734	14714	0	None	-	0	Human	4.4	pIC50	=	4.4	Binding	Displacement of [3H]LTB4 from LTB4 receptor in human neutrophilsDisplacement of [3H]LTB4 from LTB4 receptor in human neutrophils	ChEMBL	504	4	2	7	4.1	CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@]1(C)OCc3c(OS(=O)(=O)O)ccc(OS(=O)(=O)O)c3C[C@H]21	10.1021/np50120a024
	10022413	27436	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	376	9	2	4	5.0	Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136991	27436	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	376	9	2	4	5.0	Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10170399	14638	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer upon incubation for 1 hr at 37 degree C; (n=4)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer upon incubation for 1 hr at 37 degree C; (n=4)	ChEMBL	1018	33	4	16	7.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)c1ccc(N/N=C/c2ccccc2S(=O)(=O)O)nc1	10.1021/jm050383h
	CHEMBL1207275	14638	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer upon incubation for 1 hr at 37 degree C; (n=4)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer upon incubation for 1 hr at 37 degree C; (n=4)	ChEMBL	1018	33	4	16	7.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)c1ccc(N/N=C/c2ccccc2S(=O)(=O)O)nc1	10.1021/jm050383h
	CHEMBL384950	14638	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer upon incubation for 1 hr at 37 degree C; (n=4)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer upon incubation for 1 hr at 37 degree C; (n=4)	ChEMBL	1018	33	4	16	7.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)c1ccc(N/N=C/c2ccccc2S(=O)(=O)O)nc1	10.1021/jm050383h
	15666610	7808	1	None	-	0	Human	5.4	pIC50	=	5.4	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	316	10	1	2	5.1	O=C(O)CCCCCc1sccc1CCCc1ccccc1	10.1021/jm00095a011
	CHEMBL109016	7808	1	None	-	0	Human	5.4	pIC50	=	5.4	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	316	10	1	2	5.1	O=C(O)CCCCCc1sccc1CCCc1ccccc1	10.1021/jm00095a011
	44385160	61008	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.0	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2C)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL176748	61008	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.0	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2C)cc1	10.1016/S0960-894X(97)00134-0
	19427041	14459	0	None	-	1	Human	7.3	pIC50	=	7.3	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	534	14	3	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL1205171	14459	0	None	-	1	Human	7.3	pIC50	=	7.3	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	534	14	3	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL60881	14459	0	None	-	1	Human	7.3	pIC50	=	7.3	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	534	14	3	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	10023244	25942	1	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	389	9	1	3	6.1	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL135671	25942	1	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	389	9	1	3	6.1	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10047140	27385	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2cccc(Cl)c2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL136960	27385	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2cccc(Cl)c2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10475503	27784	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	390	9	2	4	5.3	CC(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137247	27784	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	390	9	2	4	5.3	CC(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10318241	28121	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	390	10	2	4	5.5	CNc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137472	28121	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	390	10	2	4	5.5	CNc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10001576	28154	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccc(Cl)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137494	28154	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccc(Cl)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10436331	120020	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	509	13	2	7	5.0	CCCc1c(OCCCOc2ccc(-c3c[nH]nn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL354553	120020	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	509	13	2	7	5.0	CCCc1c(OCCCOc2ccc(-c3c[nH]nn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	15237280	57780	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	511	13	2	6	4.6	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL167474	57780	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	511	13	2	6	4.6	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	3368	1146	18	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Tested for binding activity against [3H]LTB4 to whole human neutrophil with halh maximal inhibitionTested for binding activity against [3H]LTB4 to whole human neutrophil with halh maximal inhibition	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	9867257	1146	18	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Tested for binding activity against [3H]LTB4 to whole human neutrophil with halh maximal inhibitionTested for binding activity against [3H]LTB4 to whole human neutrophil with halh maximal inhibition	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	CHEMBL51770	1146	18	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Tested for binding activity against [3H]LTB4 to whole human neutrophil with halh maximal inhibitionTested for binding activity against [3H]LTB4 to whole human neutrophil with halh maximal inhibition	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	135543742	203667	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	410	11	3	5	4.2	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1cccc(CCC(=O)O)c1	10.1021/jm00041a021
	CHEMBL79991	203667	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	410	11	3	5	4.2	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1cccc(CCC(=O)O)c1	10.1021/jm00041a021
	44348541	16626	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsCompound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cells	ChEMBL	323	7	1	2	3.0	CN(CCc1ccccc1)C(=O)Cc1cccc(/C=C/C(=O)O)c1	10.1021/jm9506985
	CHEMBL124717	16626	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsCompound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cells	ChEMBL	323	7	1	2	3.0	CN(CCc1ccccc1)C(=O)Cc1cccc(/C=C/C(=O)O)c1	10.1021/jm9506985
	44357534	26520	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	385	9	0	6	4.7	c1ccc(-c2cc(OCCCCCn3cnnn3)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136243	26520	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	385	9	0	6	4.7	c1ccc(-c2cc(OCCCCCn3cnnn3)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10341135	29160	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	403	10	1	3	6.5	CC(C)(CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL138380	29160	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	403	10	1	3	6.5	CC(C)(CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10427789	27717	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	347	8	1	3	5.0	O=C(O)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137201	27717	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	347	8	1	3	5.0	O=C(O)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10363959	28286	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	406	10	1	5	5.3	O=C(O)CCCCCOc1cc(-c2ccc([N+](=O)[O-])cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137594	28286	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	406	10	1	5	5.3	O=C(O)CCCCCOc1cc(-c2ccc([N+](=O)[O-])cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10387480	27788	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	421	8	1	5	5.6	CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)c1nnn[nH]1	10.1021/jm00101a007
	CHEMBL137248	27788	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	421	8	1	5	5.6	CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)c1nnn[nH]1	10.1021/jm00101a007
	11725988	27763	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	359	8	1	5	4.2	c1ccc(-c2cc(OCCCCCc3nnn[nH]3)nc3ccccc23)cc1	10.1021/jm00101a007
	CHEMBL137234	27763	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	359	8	1	5	4.2	c1ccc(-c2cc(OCCCCCc3nnn[nH]3)nc3ccccc23)cc1	10.1021/jm00101a007
	10340408	118047	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	391	10	1	4	5.4	COc1cccc(-c2cc(-c3ccccc3)cc(OCCCCCC(=O)O)n2)c1	10.1021/jm00101a008
	CHEMBL341565	118047	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	391	10	1	4	5.4	COc1cccc(-c2cc(-c3ccccc3)cc(OCCCCCC(=O)O)n2)c1	10.1021/jm00101a008
	18373300	118807	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	492	8	1	5	6.5	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc([N+](=O)[O-])cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL344176	118807	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	492	8	1	5	6.5	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc([N+](=O)[O-])cc12	10.1016/j.bmcl.2003.08.070
	15666581	5557	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	346	11	2	3	5.2	O=C(O)CCCCCCc1csc(CCCc2ccc(O)cc2)c1	10.1021/jm00095a011
	CHEMBL107781	5557	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	346	11	2	3	5.2	O=C(O)CCCCCCc1csc(CCCc2ccc(O)cc2)c1	10.1021/jm00095a011
	10391552	119803	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	508	13	2	6	5.6	CCCc1c(OCCCOc2ccc(-c3c[nH]cn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL352863	119803	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	508	13	2	6	5.6	CCCc1c(OCCCOc2ccc(-c3c[nH]cn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	135507183	203919	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	396	10	3	5	3.8	CCc1cc(-c2ccn[nH]2)c(O)cc1OCCCOc1ccc(CC(=O)O)cc1	10.1021/jm00041a021
	CHEMBL81817	203919	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	396	10	3	5	3.8	CCc1cc(-c2ccn[nH]2)c(O)cc1OCCCOc1ccc(CC(=O)O)cc1	10.1021/jm00041a021
	44403823	161384	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)	ChEMBL	3125	109	25	54	-4.2	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](NC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	CHEMBL415548	161384	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)	ChEMBL	3125	109	25	54	-4.2	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](NC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	135507225	103731	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	424	12	3	5	4.6	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCOc1ccc(CC(=O)O)cc1	10.1021/jm00041a021
	CHEMBL309883	103731	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	424	12	3	5	4.6	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCOc1ccc(CC(=O)O)cc1	10.1021/jm00041a021
	10247237	28260	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	349	8	1	3	5.2	CC(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL137570	28260	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	349	8	1	3	5.2	CC(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	10032156	58693	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	647	16	1	8	8.6	CCCc1c(OCCCOc2ccc(-c3csc(SCc4ccccc4)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL169246	58693	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	647	16	1	8	8.6	CCCc1c(OCCCOc2ccc(-c3csc(SCc4ccccc4)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	9906324	14435	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205046	14435	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL46820	14435	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	9906324	14435	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80454-0
	CHEMBL1205046	14435	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80454-0
	CHEMBL46820	14435	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80454-0
	9865985	28446	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	405	9	1	5	5.2	O=C(O)CCCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137759	28446	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	405	9	1	5	5.2	O=C(O)CCCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1	10.1021/jm00101a008
	9978895	118458	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor of human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor of human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL342416	118458	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor of human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor of human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	6450158	186581	14	None	-	1	Human	8.2	pIC50	=	8.2	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	CHEMBL49210	186581	14	None	-	1	Human	8.2	pIC50	=	8.2	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	6450158	186581	14	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1021/jm00064a006
	CHEMBL49210	186581	14	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1021/jm00064a006
	135516891	156962	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	384	10	3	6	3.8	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1	10.1021/jm00041a021
	CHEMBL407983	156962	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	384	10	3	6	3.8	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1	10.1021/jm00041a021
	18963040	14684	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL1207571	14684	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL416259	14684	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	10364772	27934	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	419	9	1	5	5.4	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137341	27934	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	419	9	1	5	5.4	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10092630	27598	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	404	9	2	4	5.7	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137104	27598	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	404	9	2	4	5.7	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	132425	6772	4	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	358	11	1	2	6.1	CC(C)(CCCCCc1sccc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	CHEMBL108415	6772	4	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	358	11	1	2	6.1	CC(C)(CCCCCc1sccc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	11799000	16971	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Compound was evaluated for LTB4 receptor binding, obtained from radioligand binding assay using human intact neutrophils PMNCompound was evaluated for LTB4 receptor binding, obtained from radioligand binding assay using human intact neutrophils PMN	ChEMBL	482	9	1	4	5.1	CN(O)C(=O)c1cc(CC(=O)N(C)CCc2ccccc2)c2cccc(OCc3ccccc3)c2c1	10.1021/jm950699x
	CHEMBL125611	16971	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Compound was evaluated for LTB4 receptor binding, obtained from radioligand binding assay using human intact neutrophils PMNCompound was evaluated for LTB4 receptor binding, obtained from radioligand binding assay using human intact neutrophils PMN	ChEMBL	482	9	1	4	5.1	CN(O)C(=O)c1cc(CC(=O)N(C)CCc2ccccc2)c2cccc(OCc3ccccc3)c2c1	10.1021/jm950699x
	10319829	25898	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	417	11	1	3	6.9	CC(C)(CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL135612	25898	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	417	11	1	3	6.9	CC(C)(CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10363959	28286	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	406	10	1	5	5.3	O=C(O)CCCCCOc1cc(-c2ccc([N+](=O)[O-])cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137594	28286	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	406	10	1	5	5.3	O=C(O)CCCCCOc1cc(-c2ccc([N+](=O)[O-])cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	15666631	7988	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	346	11	2	3	5.0	O=C(O)CCCCCC(O)c1sccc1CCCc1ccccc1	10.1021/jm00095a011
	CHEMBL109128	7988	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	346	11	2	3	5.0	O=C(O)CCCCCC(O)c1sccc1CCCc1ccccc1	10.1021/jm00095a011
	44379572	119781	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	540	10	2	4	5.3	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccc(N=[N+]=[N-])c(I)c2)C1	10.1016/s0960-894x(00)00103-7
	CHEMBL352717	119781	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	540	10	2	4	5.3	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccc(N=[N+]=[N-])c(I)c2)C1	10.1016/s0960-894x(00)00103-7
	9849151	58772	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	508	13	2	6	5.6	CCCc1c(OCCCOc2ccc(-c3cc[nH]n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL169683	58772	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	508	13	2	6	5.6	CCCc1c(OCCCOc2ccc(-c3cc[nH]n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	15839731	49171	0	None	-	1	Human	7.2	pIC50	=	7.2	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	430	13	2	6	4.4	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OCC(=O)O	10.1016/S0960-894X(00)80304-2
	CHEMBL15648	49171	0	None	-	1	Human	7.2	pIC50	=	7.2	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	430	13	2	6	4.4	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OCC(=O)O	10.1016/S0960-894X(00)80304-2
	10339300	129690	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	373	6	2	3	4.7	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL367943	129690	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	373	6	2	3	4.7	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	10341242	27927	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	405	10	1	4	5.7	COc1cccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)c1	10.1021/jm00101a008
	CHEMBL137336	27927	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	405	10	1	4	5.7	COc1cccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)c1	10.1021/jm00101a008
	10477988	27917	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	433	9	1	5	5.8	CC(C)(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137330	27917	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	433	9	1	5	5.8	CC(C)(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	44357546	116240	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	399	9	0	6	5.2	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)n1cnnn1	10.1021/jm00101a008
	CHEMBL337563	116240	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	399	9	0	6	5.2	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)n1cnnn1	10.1021/jm00101a008
	9911868	17835	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibitory concentration of compound against Leukotriene B4 receptor binding to human neutrophils was determinedInhibitory concentration of compound against Leukotriene B4 receptor binding to human neutrophils was determined	ChEMBL	455	11	1	7	4.9	COc1cc(C(=O)N(C(C)C)C(C)C)ccc1OCCCCOc1ccc2c(N)noc2c1	10.1016/S0960-894X(97)00025-5
	CHEMBL126463	17835	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibitory concentration of compound against Leukotriene B4 receptor binding to human neutrophils was determinedInhibitory concentration of compound against Leukotriene B4 receptor binding to human neutrophils was determined	ChEMBL	455	11	1	7	4.9	COc1cc(C(=O)N(C(C)C)C(C)C)ccc1OCCCCOc1ccc2c(N)noc2c1	10.1016/S0960-894X(97)00025-5
	15666586	108067	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	344	11	1	2	5.8	Cc1cc(CCCCCCC(=O)O)c(CCCc2ccccc2)s1	10.1021/jm00095a011
	CHEMBL320258	108067	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	344	11	1	2	5.8	Cc1cc(CCCCCCC(=O)O)c(CCCc2ccccc2)s1	10.1021/jm00095a011
	44379573	57779	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	414	10	2	4	4.7	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccc(N=[N+]=[N-])cc2)C1	10.1016/s0960-894x(00)00103-7
	CHEMBL167465	57779	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	414	10	2	4	4.7	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccc(N=[N+]=[N-])cc2)C1	10.1016/s0960-894x(00)00103-7
	10019853	28309	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	335	8	1	3	4.9	O=C(O)CCCCCOc1cc(-c2ccccc2)c2ccccc2n1	10.1021/jm00101a007
	CHEMBL137625	28309	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	335	8	1	3	4.9	O=C(O)CCCCCOc1cc(-c2ccccc2)c2ccccc2n1	10.1021/jm00101a007
	10337448	27882	1	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	342	8	0	3	5.9	N#CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137307	27882	1	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	342	8	0	3	5.9	N#CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	9841175	14465	0	None	-	0	Human	4.2	pIC50	=	4.2	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	CHEMBL1205297	14465	0	None	-	0	Human	4.2	pIC50	=	4.2	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	CHEMBL77513	14465	0	None	-	0	Human	4.2	pIC50	=	4.2	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	44315539	14613	0	None	-	0	Human	4.2	pIC50	=	4.2	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	312	10	3	3	3.7	CCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CCCC(=O)O)C1	10.1016/0960-894X(96)00424-6
	CHEMBL1206776	14613	0	None	-	0	Human	4.2	pIC50	=	4.2	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	312	10	3	3	3.7	CCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CCCC(=O)O)C1	10.1016/0960-894X(96)00424-6
	CHEMBL305933	14613	0	None	-	0	Human	4.2	pIC50	=	4.2	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	312	10	3	3	3.7	CCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CCCC(=O)O)C1	10.1016/0960-894X(96)00424-6
	135430350	167480	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	452	13	3	5	5.2	CCCc1ccc(CCC(=O)O)cc1OCCCOc1cc(O)c(-c2cc[nH]n2)cc1CC	10.1021/jm00041a021
	CHEMBL432363	167480	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	452	13	3	5	5.2	CCCc1ccc(CCC(=O)O)cc1OCCCOc1cc(O)c(-c2cc[nH]n2)cc1CC	10.1021/jm00041a021
	10021742	9350	4	None	-	1	Human	6.1	pIC50	=	6.1	Binding	Binding affinity to LTB4 receptor in human U937 cells by whole cell assayBinding affinity to LTB4 receptor in human U937 cells by whole cell assay	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	CHEMBL111825	9350	4	None	-	1	Human	6.1	pIC50	=	6.1	Binding	Binding affinity to LTB4 receptor in human U937 cells by whole cell assayBinding affinity to LTB4 receptor in human U937 cells by whole cell assay	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	10349070	130353	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	630	16	2	7	7.9	CCCc1c(OCCCOc2ccc(-c3c[nH]c(SCc4ccccc4)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL368540	130353	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	630	16	2	7	7.9	CCCc1c(OCCCOc2ccc(-c3c[nH]c(SCc4ccccc4)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	10481412	59458	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	509	13	1	7	5.9	CCCc1c(OCCCOc2ccc(-c3ccno3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL172628	59458	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	509	13	1	7	5.9	CCCc1c(OCCCOc2ccc(-c3ccno3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	44384957	165674	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	389	7	2	4	4.3	COc1ccc(C(=O)O)cc1NC(=O)CC(=O)c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL426773	165674	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	389	7	2	4	4.3	COc1ccc(C(=O)O)cc1NC(=O)CC(=O)c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	44403368	160768	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)	ChEMBL	2750	92	21	47	-1.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](N)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	CHEMBL412510	160768	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)	ChEMBL	2750	92	21	47	-1.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](N)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	3368	1146	18	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingCompound was tested for inhibitory activity against Leukotriene B4 receptor binding	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm960088k
	9867257	1146	18	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingCompound was tested for inhibitory activity against Leukotriene B4 receptor binding	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm960088k
	CHEMBL51770	1146	18	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingCompound was tested for inhibitory activity against Leukotriene B4 receptor binding	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm960088k
	9958915	57800	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@@H](CCC(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL167669	57800	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@@H](CCC(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	10741106	117286	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Compound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membraneCompound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membrane	ChEMBL	426	9	0	4	4.7	CN(CCc1ccccc1)C(=O)Cn1cc(C=O)c2cc(OCc3ccccc3)ccc21	10.1021/jm950699x
	CHEMBL340180	117286	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Compound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membraneCompound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membrane	ChEMBL	426	9	0	4	4.7	CN(CCc1ccccc1)C(=O)Cn1cc(C=O)c2cc(OCc3ccccc3)ccc21	10.1021/jm950699x
	15666623	167222	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	434	12	1	2	7.8	CC(C)(CCCCCc1sc(-c2ccccc2)cc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	CHEMBL430520	167222	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	434	12	1	2	7.8	CC(C)(CCCCCc1sc(-c2ccccc2)cc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	9841175	14465	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	CHEMBL1205297	14465	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	CHEMBL77513	14465	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	11740566	118929	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	381	8	1	3	5.7	CC(C)(CCCCOc1cc(-c2ccccc2F)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL345047	118929	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	381	8	1	3	5.7	CC(C)(CCCCOc1cc(-c2ccccc2F)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	9934500	165038	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	472	7	1	4	6.4	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C#N)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL424290	165038	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	472	7	1	4	6.4	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C#N)cc12	10.1016/j.bmcl.2003.08.070
	44315583	14464	0	None	-	0	Human	5.1	pIC50	=	5.1	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	284	8	3	3	2.9	CCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CC(=O)O)C1	10.1016/0960-894X(96)00424-6
	CHEMBL1205289	14464	0	None	-	0	Human	5.1	pIC50	=	5.1	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	284	8	3	3	2.9	CCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CC(=O)O)C1	10.1016/0960-894X(96)00424-6
	CHEMBL76530	14464	0	None	-	0	Human	5.1	pIC50	=	5.1	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	284	8	3	3	2.9	CCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CC(=O)O)C1	10.1016/0960-894X(96)00424-6
	9976891	27941	0	None	-	0	Human	5.1	pIC50	=	5.1	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	377	8	1	3	5.9	Cc1c(OCCCCC(C)(C)C(=O)O)nc2ccccc2c1-c1ccccc1	10.1021/jm00101a007
	CHEMBL137346	27941	0	None	-	0	Human	5.1	pIC50	=	5.1	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	377	8	1	3	5.9	Cc1c(OCCCCC(C)(C)C(=O)O)nc2ccccc2c1-c1ccccc1	10.1021/jm00101a007
	135543741	203874	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	410	11	3	5	4.7	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCOc1ccc(C(=O)O)cc1	10.1021/jm00041a021
	CHEMBL81489	203874	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	410	11	3	5	4.7	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCOc1ccc(C(=O)O)cc1	10.1021/jm00041a021
	44385920	61038	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	343	5	2	2	4.7	O=C(/C=C/c1ccc(-c2ccccc2)cc1)Nc1ccccc1C(=O)O	10.1016/S0960-894X(97)00134-0
	CHEMBL176974	61038	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	343	5	2	2	4.7	O=C(/C=C/c1ccc(-c2ccccc2)cc1)Nc1ccccc1C(=O)O	10.1016/S0960-894X(97)00134-0
	15718085	100862	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1cc2oc3ccc(C(=O)O)cc3c(=O)c2cc1CCC(=O)O	10.1021/jm00064a006
	CHEMBL296869	100862	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1cc2oc3ccc(C(=O)O)cc3c(=O)c2cc1CCC(=O)O	10.1021/jm00064a006
	135507273	203574	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	452	13	3	5	5.2	CCCc1c(CCC(=O)O)cccc1OCCCOc1cc(O)c(-c2cc[nH]n2)cc1CC	10.1021/jm00041a021
	CHEMBL79233	203574	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	452	13	3	5	5.2	CCCc1c(CCC(=O)O)cccc1OCCCOc1cc(O)c(-c2cc[nH]n2)cc1CC	10.1021/jm00041a021
	122023	50508	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80999-9
	CHEMBL15766	50508	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80999-9
	CHEMBL45460	50508	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80999-9
	4534	191295	89	None	-	0	Human	7.1	pIC50	=	7.1	Binding	The compound was tested for its inhibitory activity against LTB4 in human PMNThe compound was tested for its inhibitory activity against LTB4 in human PMN	ChEMBL	302	5	4	4	3.6	CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1	10.1021/jm00085a019
	CHEMBL52	191295	89	None	-	0	Human	7.1	pIC50	=	7.1	Binding	The compound was tested for its inhibitory activity against LTB4 in human PMNThe compound was tested for its inhibitory activity against LTB4 in human PMN	ChEMBL	302	5	4	4	3.6	CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1	10.1021/jm00085a019
	122023	50508	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL15766	50508	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL45460	50508	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	122023	50508	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80304-2
	CHEMBL15766	50508	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80304-2
	CHEMBL45460	50508	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80304-2
	122023	50508	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1021/jm00041a021
	CHEMBL15766	50508	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1021/jm00041a021
	CHEMBL45460	50508	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1021/jm00041a021
	135500104	163210	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	410	11	3	5	4.2	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1ccc(CCC(=O)O)cc1	10.1021/jm00041a021
	CHEMBL420576	163210	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	410	11	3	5	4.2	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1ccc(CCC(=O)O)cc1	10.1021/jm00041a021
	10347709	58778	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	557	13	2	8	6.6	CCCc1c(OCCCOc2ccc(-c3csc(S)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL169722	58778	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	557	13	2	8	6.6	CCCc1c(OCCCOc2ccc(-c3csc(S)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	135457469	105147	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	398	10	2	7	3.8	CCc1cc(-c2ccn(C)n2)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1	10.1021/jm00041a021
	CHEMBL312483	105147	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	398	10	2	7	3.8	CCc1cc(-c2ccn(C)n2)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1	10.1021/jm00041a021
	10092630	27598	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	404	9	2	4	5.7	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137104	27598	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	404	9	2	4	5.7	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10737187	15329	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsCompound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cells	ChEMBL	359	8	0	2	4.5	CN(CCc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2)cc1	10.1021/jm9506985
	CHEMBL121748	15329	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsCompound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cells	ChEMBL	359	8	0	2	4.5	CN(CCc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2)cc1	10.1021/jm9506985
	18373357	116280	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	461	7	1	3	6.9	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL337790	116280	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	461	7	1	3	6.9	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C)cc12	10.1016/j.bmcl.2003.08.070
	44386171	61030	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	377	5	2	2	5.4	O=C(/C=C/c1ccc(-c2ccccc2)cc1)Nc1cc(C(=O)O)ccc1Cl	10.1016/S0960-894X(97)00134-0
	CHEMBL176903	61030	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	377	5	2	2	5.4	O=C(/C=C/c1ccc(-c2ccccc2)cc1)Nc1cc(C(=O)O)ccc1Cl	10.1016/S0960-894X(97)00134-0
	10052575	58631	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	525	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL168944	58631	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	525	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	44385966	60090	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	4.8	COc1ccc(C(=O)O)cc1NC(=O)[C@H]1C[C@@H]1c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL175128	60090	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	4.8	COc1ccc(C(=O)O)cc1NC(=O)[C@H]1C[C@@H]1c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	192617	100271	16	None	-	1	Human	10.4	pKi	=	10.4	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL292782	100271	16	None	-	1	Human	10.4	pKi	=	10.4	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	192617	100271	16	None	-	1	Human	10.4	pKi	=	10.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL292782	100271	16	None	-	1	Human	10.4	pKi	=	10.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	19600933	201103	0	None	-	1	Human	10.1	pKi	=	10.1	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	534	13	3	5	5.8	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc(C#CCCC(=O)O)cc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL62265	201103	0	None	-	1	Human	10.1	pKi	=	10.1	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	534	13	3	5	5.8	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc(C#CCCC(=O)O)cc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	10745838	117546	0	None	-	1	Human	10.0	pKi	=	10.0	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	582	12	3	7	6.4	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL340460	117546	0	None	-	1	Human	10.0	pKi	=	10.0	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	582	12	3	7	6.4	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	2487	2326	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	5280492	2326	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL65061	2326	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	DB12961	2326	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	2487	2326	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	5280492	2326	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL65061	2326	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	DB12961	2326	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	2487	2326	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	5280492	2326	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	CHEMBL65061	2326	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	DB12961	2326	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	132379	111227	13	None	-	1	Human	9.9	pKi	=	9.9	Binding	Affinity for guinea pig PMN LTB-4 receptors.Affinity for guinea pig PMN LTB-4 receptors.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	CHEMBL328712	111227	13	None	-	1	Human	9.9	pKi	=	9.9	Binding	Affinity for guinea pig PMN LTB-4 receptors.Affinity for guinea pig PMN LTB-4 receptors.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	10120811	95992	0	None	-	1	Human	9.9	pKi	=	9.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cccc(Oc2ccc(C(=O)O)cc2)c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL262231	95992	0	None	-	1	Human	9.9	pKi	=	9.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cccc(Oc2ccc(C(=O)O)cc2)c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	192617	100271	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00046a017
	CHEMBL292782	100271	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00046a017
	192617	100271	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm960088k
	CHEMBL292782	100271	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm960088k
	192617	100271	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL292782	100271	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	192617	100271	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL292782	100271	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	10745838	117546	0	None	-	1	Human	9.2	pKi	=	9.2	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	582	12	3	7	6.4	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL340460	117546	0	None	-	1	Human	9.2	pKi	=	9.2	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	582	12	3	7	6.4	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	6441619	205045	13	None	-	1	Human	9.1	pKi	=	9.1	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960248s
	CHEMBL90214	205045	13	None	-	1	Human	9.1	pKi	=	9.1	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960248s
	6441619	205045	13	None	-	1	Human	9.1	pKi	=	9.1	Binding	Compound was tested for binding affinity against human neutrophil LTB4 (leukotriene) receptorCompound was tested for binding affinity against human neutrophil LTB4 (leukotriene) receptor	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960088k
	CHEMBL90214	205045	13	None	-	1	Human	9.1	pKi	=	9.1	Binding	Compound was tested for binding affinity against human neutrophil LTB4 (leukotriene) receptorCompound was tested for binding affinity against human neutrophil LTB4 (leukotriene) receptor	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960088k
	9850643	205942	0	None	-	1	Human	9.0	pKi	=	9	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	554	19	2	6	6.4	CCCc1c(OCCCCCCc2cccc(OCCCCC(=O)O)c2CCC(=O)O)ccc2c1OCCC2=O	10.1021/jm00046a017
	CHEMBL95453	205942	0	None	-	1	Human	9.0	pKi	=	9	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	554	19	2	6	6.4	CCCc1c(OCCCCCCc2cccc(OCCCCC(=O)O)c2CCC(=O)O)ccc2c1OCCC2=O	10.1021/jm00046a017
	15658147	9478	0	None	-	1	Human	9.0	pKi	=	9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	411	13	3	4	5.2	CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a013
	CHEMBL112487	9478	0	None	-	1	Human	9.0	pKi	=	9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	411	13	3	4	5.2	CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a013
	CHEMBL112520	9478	0	None	-	1	Human	9.0	pKi	=	9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	411	13	3	4	5.2	CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a013
	9850974	204534	0	None	-	1	Human	9.0	pKi	=	9	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	568	20	2	6	6.8	CCCc1c(OCCCCCCc2cccc(OCCCCCC(=O)O)c2CCC(=O)O)ccc2c1OCCC2=O	10.1021/jm960088k
	CHEMBL86900	204534	0	None	-	1	Human	9.0	pKi	=	9	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	568	20	2	6	6.8	CCCc1c(OCCCCCCc2cccc(OCCCCCC(=O)O)c2CCC(=O)O)ccc2c1OCCC2=O	10.1021/jm960088k
	15658147	9478	0	None	-	1	Human	9.0	pKi	=	9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	411	13	3	4	5.2	CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a012
	CHEMBL112487	9478	0	None	-	1	Human	9.0	pKi	=	9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	411	13	3	4	5.2	CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a012
	CHEMBL112520	9478	0	None	-	1	Human	9.0	pKi	=	9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	411	13	3	4	5.2	CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a012
	10120811	95992	0	None	-	1	Human	9.0	pKi	=	9.0	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cccc(Oc2ccc(C(=O)O)cc2)c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL262231	95992	0	None	-	1	Human	9.0	pKi	=	9.0	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cccc(Oc2ccc(C(=O)O)cc2)c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	19600933	201103	0	None	-	1	Human	9.0	pKi	=	9.0	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	534	13	3	5	5.8	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc(C#CCCC(=O)O)cc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL62265	201103	0	None	-	1	Human	9.0	pKi	=	9.0	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	534	13	3	5	5.8	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc(C#CCCC(=O)O)cc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	9893718	204765	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL292768	204765	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL88337	204765	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	10529082	18615	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	489	10	1	5	6.4	COc1ccc(CCOc2ccc(CSc3c(Cl)cccc3Cl)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	CHEMBL127913	18615	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	489	10	1	5	6.4	COc1ccc(CCOc2ccc(CSc3c(Cl)cccc3Cl)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	9893718	204765	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL292768	204765	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL88337	204765	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	204058	162895	5	None	-	1	Human	8.9	pKi	=	8.9	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@H](CCC(=O)O)CC2	10.1021/jm00046a017
	CHEMBL419948	162895	5	None	-	1	Human	8.9	pKi	=	8.9	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@H](CCC(=O)O)CC2	10.1021/jm00046a017
	10529241	18311	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	493	9	1	4	7.1	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccc(Cl)cc1	10.1021/jm960248s
	CHEMBL127376	18311	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	493	9	1	4	7.1	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccc(Cl)cc1	10.1021/jm960248s
	10648186	17968	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	473	10	1	4	6.8	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCCc1ccccc1	10.1021/jm960248s
	CHEMBL126976	17968	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	473	10	1	4	6.8	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCCc1ccccc1	10.1021/jm960248s
	11798848	16340	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	477	9	1	4	6.5	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccc(F)cc1	10.1021/jm960248s
	CHEMBL123722	16340	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	477	9	1	4	6.5	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccc(F)cc1	10.1021/jm960248s
	9958441	116321	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	517	12	1	5	7.2	COc1ccc(CCCCOc2ccc(CSc3c(Cl)cccc3Cl)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	CHEMBL337995	116321	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	517	12	1	5	7.2	COc1ccc(CCCCOc2ccc(CSc3c(Cl)cccc3Cl)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	2487	2326	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	5280492	2326	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL65061	2326	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	DB12961	2326	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	2487	2326	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	5280492	2326	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	CHEMBL65061	2326	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	DB12961	2326	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	18963032	100610	0	None	-	1	Human	8.7	pKi	=	8.7	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	444	11	2	6	4.5	CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	CHEMBL294987	100610	0	None	-	1	Human	8.7	pKi	=	8.7	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	444	11	2	6	4.5	CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	44340787	14397	0	None	-	1	Human	8.0	pKi	=	8	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	435	12	3	4	6.0	CCCCCCCCC(O)c1ccc2ccc(CC(O)c3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL1204561	14397	0	None	-	1	Human	8.0	pKi	=	8	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	435	12	3	4	6.0	CCCCCCCCC(O)c1ccc2ccc(CC(O)c3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL326397	14397	0	None	-	1	Human	8.0	pKi	=	8	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	435	12	3	4	6.0	CCCCCCCCC(O)c1ccc2ccc(CC(O)c3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	15839729	205151	1	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	CHEMBL15559	205151	1	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	CHEMBL90788	205151	1	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	10046307	14612	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	374	12	2	5	4.7	CCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1206771	14612	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	374	12	2	5	4.7	CCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL305560	14612	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	374	12	2	5	4.7	CCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	15658110	14390	0	None	-	1	Human	7.0	pKi	=	7	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	419	12	2	3	6.5	CCCCCCCCC(O)c1ccc2ccc(CCc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL113528	14390	0	None	-	1	Human	7.0	pKi	=	7	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	419	12	2	3	6.5	CCCCCCCCC(O)c1ccc2ccc(CCc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL1204495	14390	0	None	-	1	Human	7.0	pKi	=	7	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	419	12	2	3	6.5	CCCCCCCCC(O)c1ccc2ccc(CCc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	15658157	14391	0	None	-	1	Human	6.0	pKi	=	6	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	449	12	3	5	4.9	CCCCOc1cccc(C(O)CCc2cccc(CC(O)c3cccc(C(=O)O)c3)n2)c1	10.1021/jm00074a012
	CHEMBL114454	14391	0	None	-	1	Human	6.0	pKi	=	6	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	449	12	3	5	4.9	CCCCOc1cccc(C(O)CCc2cccc(CC(O)c3cccc(C(=O)O)c3)n2)c1	10.1021/jm00074a012
	CHEMBL1204496	14391	0	None	-	1	Human	6.0	pKi	=	6	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	449	12	3	5	4.9	CCCCOc1cccc(C(O)CCc2cccc(CC(O)c3cccc(C(=O)O)c3)n2)c1	10.1021/jm00074a012
	10037501	184131	3	None	-	1	Human	4.0	pKi	=	4	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	245	1	1	5	0.5	CN1C(=O)/C(=C/c2ccc3c(c2)OCO3)N=C1N	10.1021/np50100a005
	CHEMBL485053	184131	3	None	-	1	Human	4.0	pKi	=	4	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	245	1	1	5	0.5	CN1C(=O)/C(=C/c2ccc3c(c2)OCO3)N=C1N	10.1021/np50100a005
	18963059	14440	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	402	11	2	6	4.7	CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205055	14440	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	402	11	2	6	4.7	CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL47726	14440	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	402	11	2	6	4.7	CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	14977959	9381	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	506	15	2	5	6.0	Nc1cccc([S+]([O-])Cc2ccc(OCCCCCCCCc3ccccc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	CHEMBL112018	9381	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	506	15	2	5	6.0	Nc1cccc([S+]([O-])Cc2ccc(OCCCCCCCCc3ccccc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	18963030	14439	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	442	12	2	6	5.1	CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205054	14439	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	442	12	2	6	5.1	CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL47725	14439	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	442	12	2	6	5.1	CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	21765776	163128	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3ccccc3C(=O)O)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL420488	163128	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3ccccc3C(=O)O)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	14977907	9444	0	None	-	1	Human	6.0	pKi	=	6.0	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	483	18	2	5	6.8	CCCCCCCCCCCCOc1ccc(COc2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL112310	9444	0	None	-	1	Human	6.0	pKi	=	6.0	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	483	18	2	5	6.8	CCCCCCCCCCCCOc1ccc(COc2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	14977965	110848	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	524	15	2	5	6.2	Nc1cccc([S+]([O-])Cc2ccc(OCCCCCCCCc3ccc(F)cc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	CHEMBL326909	110848	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	524	15	2	5	6.2	Nc1cccc([S+]([O-])Cc2ccc(OCCCCCCCCc3ccc(F)cc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	11798329	18304	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	463	8	1	4	6.5	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCc1ccc(F)cc1	10.1021/jm960248s
	CHEMBL127341	18304	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	463	8	1	4	6.5	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCc1ccc(F)cc1	10.1021/jm960248s
	11800543	19179	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	538	11	2	6	6.7	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL129272	19179	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	538	11	2	6	6.7	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	122023	50508	56	None	-	1	Human	6.9	pKi	=	6.9	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL15766	50508	56	None	-	1	Human	6.9	pKi	=	6.9	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL45460	50508	56	None	-	1	Human	6.9	pKi	=	6.9	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	23257866	9360	0	None	-	1	Human	6.9	pKi	=	6.9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	515	18	2	5	6.5	CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL111908	9360	0	None	-	1	Human	6.9	pKi	=	6.9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	515	18	2	5	6.5	CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	10021742	9350	4	None	-	1	Human	5.9	pKi	=	5.9	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	CHEMBL111825	9350	4	None	-	1	Human	5.9	pKi	=	5.9	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	14977963	9537	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	574	15	2	5	7.1	Nc1cccc([S+]([O-])Cc2ccc(OCCCCCCCCc3ccc(C(F)(F)F)cc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	CHEMBL112737	9537	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	574	15	2	5	7.1	Nc1cccc([S+]([O-])Cc2ccc(OCCCCCCCCc3ccc(C(F)(F)F)cc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	9829619	100272	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cc(Oc2ccc(C(=O)O)cc2)ccc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL292783	100272	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cc(Oc2ccc(C(=O)O)cc2)ccc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	9977200	29148	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	360	11	2	5	4.3	CCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL138370	29148	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	360	11	2	5	4.3	CCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL60617	29148	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	360	11	2	5	4.3	CCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	10292143	116084	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL336665	116084	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL48667	116084	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	10292143	116084	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL336665	116084	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL48667	116084	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	10292143	116084	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80454-0
	CHEMBL336665	116084	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80454-0
	CHEMBL48667	116084	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80454-0
	18963040	14684	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1207571	14684	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL416259	14684	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	15658122	9657	0	None	-	1	Human	6.9	pKi	=	6.9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	453	12	2	4	6.0	CCCCCCCCC(O)c1ccc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL113514	9657	0	None	-	1	Human	6.9	pKi	=	6.9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	453	12	2	4	6.0	CCCCCCCCC(O)c1ccc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	15658098	168739	0	None	-	1	Human	5.9	pKi	=	5.9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	383	13	2	3	6.3	CCCCCCCCC(O)c1ccc2ccc(/C=C/CCCC(=O)O)nc2c1	10.1021/jm00074a012
	CHEMBL441647	168739	0	None	-	1	Human	5.9	pKi	=	5.9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	383	13	2	3	6.3	CCCCCCCCC(O)c1ccc2ccc(/C=C/CCCC(=O)O)nc2c1	10.1021/jm00074a012
	14977952	108537	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	676	19	2	7	7.3	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(NS(=O)(=O)c4ccccc4)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL321261	108537	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	676	19	2	7	7.3	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(NS(=O)(=O)c4ccccc4)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	14977946	110078	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	531	18	2	6	6.2	CCCCCCCCCCCCOc1ccc(CS(=O)(=O)c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL325423	110078	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	531	18	2	6	6.2	CCCCCCCCCCCCOc1ccc(CS(=O)(=O)c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	44270188	51096	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	484	13	1	6	5.4	CCCc1cc(OCCCOc2ccc(C(C)=O)c(OC)c2CCC)cc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	CHEMBL15817	51096	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	484	13	1	6	5.4	CCCc1cc(OCCCOc2ccc(C(C)=O)c(OC)c2CCC)cc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	9984593	9531	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	533	17	2	5	7.3	O=C(O)/C=C/c1nc(CSCc2cccc(C(=O)O)c2)ccc1OCCCCCCCCc1ccccc1	10.1021/jm00046a017
	CHEMBL112707	9531	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	533	17	2	5	7.3	O=C(O)/C=C/c1nc(CSCc2cccc(C(=O)O)c2)ccc1OCCCCCCCCc1ccccc1	10.1021/jm00046a017
	15839733	45365	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	458	14	2	6	5.2	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(CC)C(=O)O	10.1016/S0960-894X(00)80304-2
	CHEMBL15295	45365	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	458	14	2	6	5.2	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(CC)C(=O)O	10.1016/S0960-894X(00)80304-2
	14977913	9156	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	549	17	2	6	5.7	COc1ccc(CCCCCCCCOc2ccc(COc3cccc(C(=O)O)c3)[n+]([O-])c2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL110797	9156	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	549	17	2	6	5.7	COc1ccc(CCCCCCCCOc2ccc(COc3cccc(C(=O)O)c3)[n+]([O-])c2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	14977924	110445	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	565	17	2	6	6.2	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL326192	110445	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	565	17	2	6	6.2	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10812265	57824	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	424	11	2	6	5.1	CCc1cc(-c2cccc(OC)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL167923	57824	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	424	11	2	6	5.1	CCc1cc(-c2cccc(OC)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	10475982	161263	0	None	-15	2	Human	4.8	pKi	=	4.8	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2cc(OCc3ccc4ccccc4n3)ccc2OC[C@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	CHEMBL414462	161263	0	None	-15	2	Human	4.8	pKi	=	4.8	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2cc(OCc3ccc4ccccc4n3)ccc2OC[C@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	21765774	9594	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	579	18	2	6	6.3	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])Cc3ccc(C(=O)O)cc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL113146	9594	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	579	18	2	6	6.3	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])Cc3ccc(C(=O)O)cc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	14977898	9980	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	519	15	3	6	5.3	COc1ccc(CCCCCCOc2ccc(CC(O)c3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL115437	9980	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	519	15	3	6	5.3	COc1ccc(CCCCCCOc2ccc(CC(O)c3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	14977924	110445	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	565	17	2	6	6.2	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL326192	110445	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	565	17	2	6	6.2	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	10405361	14461	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	346	10	2	5	3.9	CCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1205188	14461	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	346	10	2	5	3.9	CCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL62051	14461	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	346	10	2	5	3.9	CCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	15839732	45416	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	444	13	2	6	4.8	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(C)C(=O)O	10.1016/S0960-894X(00)80304-2
	CHEMBL15299	45416	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	444	13	2	6	4.8	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(C)C(=O)O	10.1016/S0960-894X(00)80304-2
	44382468	58764	0	None	-	1	Human	5.7	pKi	=	5.7	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	C[C@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL169639	58764	0	None	-	1	Human	5.7	pKi	=	5.7	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	C[C@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	44341107	9354	0	None	-	1	Human	4.7	pKi	=	4.7	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	277	4	1	3	3.2	Cn1c(N)nc(Cc2ccccc2)c1Cc1ccccc1	10.1021/jm00074a014
	CHEMBL111872	9354	0	None	-	1	Human	4.7	pKi	=	4.7	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	277	4	1	3	3.2	Cn1c(N)nc(Cc2ccccc2)c1Cc1ccccc1	10.1021/jm00074a014
	23257889	9396	0	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	535	17	1	6	7.5	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(OC)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL112088	9396	0	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	535	17	1	6	7.5	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(OC)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	132379	111227	13	None	-	1	Human	8.7	pKi	=	8.7	Binding	Affinity for human PMN LTB-4 receptors.Affinity for human PMN LTB-4 receptors.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	CHEMBL328712	111227	13	None	-	1	Human	8.7	pKi	=	8.7	Binding	Affinity for human PMN LTB-4 receptors.Affinity for human PMN LTB-4 receptors.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	132379	111227	13	None	-	1	Human	8.7	pKi	=	8.7	Binding	Binding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligandBinding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligand	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00070a015
	CHEMBL328712	111227	13	None	-	1	Human	8.7	pKi	=	8.7	Binding	Binding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligandBinding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligand	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00070a015
	132379	111227	13	None	-	1	Human	8.7	pKi	=	8.7	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00046a017
	CHEMBL328712	111227	13	None	-	1	Human	8.7	pKi	=	8.7	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00046a017
	10694814	16378	0	None	-	1	Human	8.6	pKi	=	8.6	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	449	12	1	5	5.9	COc1ccc(CCCCOc2ccc(CSc3ccccc3)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	CHEMBL123862	16378	0	None	-	1	Human	8.6	pKi	=	8.6	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	449	12	1	5	5.9	COc1ccc(CCCCOc2ccc(CSc3ccccc3)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	2487	2326	32	None	31	2	Human	8.5	pKi	=	8.5	Binding	Displacement of [3H]LTB4 from LTB4RDisplacement of [3H]LTB4 from LTB4R	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/np50094a001
	5280492	2326	32	None	31	2	Human	8.5	pKi	=	8.5	Binding	Displacement of [3H]LTB4 from LTB4RDisplacement of [3H]LTB4 from LTB4R	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/np50094a001
	CHEMBL65061	2326	32	None	31	2	Human	8.5	pKi	=	8.5	Binding	Displacement of [3H]LTB4 from LTB4RDisplacement of [3H]LTB4 from LTB4R	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/np50094a001
	DB12961	2326	32	None	31	2	Human	8.5	pKi	=	8.5	Binding	Displacement of [3H]LTB4 from LTB4RDisplacement of [3H]LTB4 from LTB4R	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/np50094a001
	10182429	57816	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	428	10	2	5	5.7	CCc1cc(-c2ccc(Cl)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL167850	57816	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	428	10	2	5	5.7	CCc1cc(-c2ccc(Cl)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	11800543	19179	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	538	11	2	6	6.7	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL129272	19179	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	538	11	2	6	6.7	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	18963040	14684	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1207571	14684	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL416259	14684	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	18963040	14684	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL1207571	14684	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL416259	14684	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	114999	3469	15	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00074a014
	6156	3469	15	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00074a014
	CHEMBL14823	3469	15	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00074a014
	44341141	9328	0	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	667	18	1	7	6.9	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(CS(=O)(=O)C(F)(F)F)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL111723	9328	0	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	667	18	1	7	6.9	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(CS(=O)(=O)C(F)(F)F)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	23257891	9598	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	551	17	1	6	6.5	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(OC)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL113167	9598	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	551	17	1	6	6.5	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(OC)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10325873	9413	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	579	18	2	6	6.3	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])Cc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL112169	9413	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	579	18	2	6	6.3	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])Cc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	44382378	58546	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL168854	58546	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	44341318	9443	0	None	-	1	Human	5.6	pKi	=	5.6	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	349	8	2	4	3.5	Cn1c(N)nc(Cc2ccc(CCCCO)cc2)c1Cc1ccccc1	10.1021/jm00074a014
	CHEMBL112309	9443	0	None	-	1	Human	5.6	pKi	=	5.6	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	349	8	2	4	3.5	Cn1c(N)nc(Cc2ccc(CCCCO)cc2)c1Cc1ccccc1	10.1021/jm00074a014
	23257882	109913	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	564	17	1	6	6.5	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(N(C)C)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL324478	109913	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	564	17	1	6	6.5	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(N(C)C)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10745069	29867	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	542	13	2	4	7.9	CCCc1c(Cc2ccccc2C(=O)O)cccc1OCCCOc1cc(O)c(-c2ccc(F)cc2)cc1CC	10.1021/jm00022a006
	CHEMBL138954	29867	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	542	13	2	4	7.9	CCCc1c(Cc2ccccc2C(=O)O)cccc1OCCCOc1cc(O)c(-c2ccc(F)cc2)cc1CC	10.1021/jm00022a006
	177941	1551	40	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	10.1021/jm960088k
	2948	1551	40	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	10.1021/jm960088k
	CHEMBL329123	1551	40	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	10.1021/jm960088k
	DB12850	1551	40	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	10.1021/jm960088k
	9906324	14435	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity against Guinea pig membrane LTB4 ReceptorBinding affinity against Guinea pig membrane LTB4 Receptor	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL1205046	14435	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity against Guinea pig membrane LTB4 ReceptorBinding affinity against Guinea pig membrane LTB4 Receptor	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL46820	14435	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity against Guinea pig membrane LTB4 ReceptorBinding affinity against Guinea pig membrane LTB4 Receptor	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	9906324	14435	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205046	14435	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL46820	14435	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	9906324	14435	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80454-0
	CHEMBL1205046	14435	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80454-0
	CHEMBL46820	14435	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80454-0
	14977920	9373	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	515	18	2	5	6.5	CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2ccc(C(=O)O)cc2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL111969	9373	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	515	18	2	5	6.5	CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2ccc(C(=O)O)cc2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	44341073	10018	0	None	-	1	Human	4.6	pKi	=	4.6	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	307	5	1	4	3.2	COc1cccc(Cc2nc(N)n(C)c2Cc2ccccc2)c1	10.1021/jm00074a014
	CHEMBL115679	10018	0	None	-	1	Human	4.6	pKi	=	4.6	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	307	5	1	4	3.2	COc1cccc(Cc2nc(N)n(C)c2Cc2ccccc2)c1	10.1021/jm00074a014
	10324028	9918	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	509	15	2	6	5.6	COc1ccc(CCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2CCC(=O)O)cc1	10.1021/jm00046a017
	CHEMBL115040	9918	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	509	15	2	6	5.6	COc1ccc(CCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2CCC(=O)O)cc1	10.1021/jm00046a017
	44302963	14457	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	402	14	2	5	5.5	CCCCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1205145	14457	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	402	14	2	5	5.5	CCCCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL58794	14457	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	402	14	2	5	5.5	CCCCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	9826485	105870	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity against LTB4 receptors in human PMNsBinding affinity against LTB4 receptors in human PMNs	ChEMBL	469	16	3	5	5.7	CCCCCCCCCCOc1ccc(CC(O)c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00070a015
	CHEMBL313923	105870	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity against LTB4 receptors in human PMNsBinding affinity against LTB4 receptors in human PMNs	ChEMBL	469	16	3	5	5.7	CCCCCCCCCCOc1ccc(CC(O)c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00070a015
	114999	3469	15	None	-	1	Human	6.6	pKi	=	6.6	Binding	In vitro antagonist activity against leukotriene B4 (LTB4) receptor in [3H]-LTB4 human neutrophil receptor binding assayIn vitro antagonist activity against leukotriene B4 (LTB4) receptor in [3H]-LTB4 human neutrophil receptor binding assay	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/0960-894X(95)00135-G
	6156	3469	15	None	-	1	Human	6.6	pKi	=	6.6	Binding	In vitro antagonist activity against leukotriene B4 (LTB4) receptor in [3H]-LTB4 human neutrophil receptor binding assayIn vitro antagonist activity against leukotriene B4 (LTB4) receptor in [3H]-LTB4 human neutrophil receptor binding assay	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/0960-894X(95)00135-G
	CHEMBL14823	3469	15	None	-	1	Human	6.6	pKi	=	6.6	Binding	In vitro antagonist activity against leukotriene B4 (LTB4) receptor in [3H]-LTB4 human neutrophil receptor binding assayIn vitro antagonist activity against leukotriene B4 (LTB4) receptor in [3H]-LTB4 human neutrophil receptor binding assay	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/0960-894X(95)00135-G
	15658099	162769	0	None	-	1	Human	5.6	pKi	=	5.6	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	385	14	2	3	6.2	CCCCCCCCC(O)c1ccc2ccc(CCCCCC(=O)O)nc2c1	10.1021/jm00074a012
	CHEMBL419036	162769	0	None	-	1	Human	5.6	pKi	=	5.6	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	385	14	2	3	6.2	CCCCCCCCC(O)c1ccc2ccc(CCCCCC(=O)O)nc2c1	10.1021/jm00074a012
	9826485	105870	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	469	16	3	5	5.7	CCCCCCCCCCOc1ccc(CC(O)c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL313923	105870	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	469	16	3	5	5.7	CCCCCCCCCCOc1ccc(CC(O)c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	14977927	10144	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	652	18	2	7	7.7	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(NS(=O)(=O)C(F)(F)F)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL116101	10144	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	652	18	2	7	7.7	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(NS(=O)(=O)C(F)(F)F)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	15658155	14388	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	447	11	3	5	5.0	CCCCOc1cccc(C(O)/C=C/c2cccc(CC(O)c3cccc(C(=O)O)c3)n2)c1	10.1021/jm00074a012
	CHEMBL113288	14388	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	447	11	3	5	5.0	CCCCOc1cccc(C(O)/C=C/c2cccc(CC(O)c3cccc(C(=O)O)c3)n2)c1	10.1021/jm00074a012
	CHEMBL1204493	14388	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	447	11	3	5	5.0	CCCCOc1cccc(C(O)/C=C/c2cccc(CC(O)c3cccc(C(=O)O)c3)n2)c1	10.1021/jm00074a012
	10179915	57785	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	412	10	2	5	5.2	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL167520	57785	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	412	10	2	5	5.2	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	44302965	197266	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Binding affinity to leukotriene B4 receptorBinding affinity to leukotriene B4 receptor	ChEMBL	551	14	1	7	6.5	CCCc1c(OCCCOc2ccc(-c3cscn3)c(COC)c2CC2CC2)ccc2c1O[C@@H](C(=O)O)CC2	10.1021/jm990504b
	CHEMBL58495	197266	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Binding affinity to leukotriene B4 receptorBinding affinity to leukotriene B4 receptor	ChEMBL	551	14	1	7	6.5	CCCc1c(OCCCOc2ccc(-c3cscn3)c(COC)c2CC2CC2)ccc2c1O[C@@H](C(=O)O)CC2	10.1021/jm990504b
	192624	167915	2	None	-	1	Human	8.5	pKi	=	8.5	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	394	10	2	5	5.1	CCc1cc(-c2ccccc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL435273	167915	2	None	-	1	Human	8.5	pKi	=	8.5	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	394	10	2	5	5.1	CCc1cc(-c2ccccc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	9912012	161643	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	458	12	2	6	4.9	CCCc1c(OCCCOc2cc(O)c(OCC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	CHEMBL416277	161643	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	458	12	2	6	4.9	CCCc1c(OCCCOc2cc(O)c(OCC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	9906324	14435	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Binding affinity against human neutrophil ReceptorBinding affinity against human neutrophil Receptor	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL1205046	14435	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Binding affinity against human neutrophil ReceptorBinding affinity against human neutrophil Receptor	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL46820	14435	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Binding affinity against human neutrophil ReceptorBinding affinity against human neutrophil Receptor	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	6157	2878	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm960088k
	6438358	2878	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm960088k
	CHEMBL422420	2878	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm960088k
	44302966	96039	0	None	-	1	Human	6.5	pKi	=	6.5	Binding	Binding affinity to leukotriene B4 receptorBinding affinity to leukotriene B4 receptor	ChEMBL	484	13	2	6	4.9	CCCc1c(OCCCOc2ccc3c(c2CCC)O[C@@H](C(=O)O)CC3)ccc(C(C)=O)c1CO	10.1021/jm990504b
	CHEMBL262530	96039	0	None	-	1	Human	6.5	pKi	=	6.5	Binding	Binding affinity to leukotriene B4 receptorBinding affinity to leukotriene B4 receptor	ChEMBL	484	13	2	6	4.9	CCCc1c(OCCCOc2ccc3c(c2CCC)O[C@@H](C(=O)O)CC3)ccc(C(C)=O)c1CO	10.1021/jm990504b
	10554820	30050	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	556	13	2	5	7.5	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1C(=O)c1ccccc1C(=O)O	10.1021/jm00022a006
	CHEMBL139115	30050	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	556	13	2	5	7.5	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1C(=O)c1ccccc1C(=O)O	10.1021/jm00022a006
	44302963	14457	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	402	14	2	5	5.5	CCCCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1205145	14457	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	402	14	2	5	5.5	CCCCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL58794	14457	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	402	14	2	5	5.5	CCCCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	9845585	57833	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	408	10	2	5	5.4	CCc1cc(-c2ccc(C)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL168011	57833	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	408	10	2	5	5.4	CCc1cc(-c2ccc(C)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	44382275	59410	0	None	-	1	Human	6.5	pKi	=	6.5	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	C[C@@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL172457	59410	0	None	-	1	Human	6.5	pKi	=	6.5	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	C[C@@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	44382384	59215	0	None	-	1	Human	5.5	pKi	=	5.5	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL171666	59215	0	None	-	1	Human	5.5	pKi	=	5.5	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	14977911	9493	0	None	-	1	Human	6.5	pKi	=	6.5	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	499	18	2	5	6.0	CCCCCCCCCCCCOc1ccc(COc2cccc(C(=O)O)c2)[n+]([O-])c1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL112544	9493	0	None	-	1	Human	6.5	pKi	=	6.5	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	499	18	2	5	6.0	CCCCCCCCCCCCOc1ccc(COc2cccc(C(=O)O)c2)[n+]([O-])c1/C=C/C(=O)O	10.1021/jm00074a013
	14977931	9550	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	520	16	2	6	7.0	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL112808	9550	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	520	16	2	6	7.0	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10021742	9350	4	None	-	1	Human	5.5	pKi	=	5.5	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/jm00074a014
	CHEMBL111825	9350	4	None	-	1	Human	5.5	pKi	=	5.5	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/jm00074a014
	14977957	9414	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	490	15	2	5	7.0	Nc1cccc(SCc2ccc(OCCCCCCCCc3ccccc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	CHEMBL112176	9414	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	490	15	2	5	7.0	Nc1cccc(SCc2ccc(OCCCCCCCCc3ccccc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	14977933	9782	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	552	16	2	7	5.7	COc1ccc(CCCCCCCCOc2ccc(CS(=O)(=O)c3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL114290	9782	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	552	16	2	7	5.7	COc1ccc(CCCCCCCCOc2ccc(CS(=O)(=O)c3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10507666	30687	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	592	13	2	6	7.1	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1S(=O)(=O)c1ccccc1C(=O)O	10.1021/jm00022a006
	CHEMBL139799	30687	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	592	13	2	6	7.1	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1S(=O)(=O)c1ccccc1C(=O)O	10.1021/jm00022a006
	9807782	19215	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	556	11	2	6	6.9	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL129463	19215	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	556	11	2	6	6.9	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	6444688	186727	29	None	-	1	Human	6.4	pKi	=	6.4	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00074a014
	CHEMBL49302	186727	29	None	-	1	Human	6.4	pKi	=	6.4	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00074a014
	23257894	9549	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	521	16	1	5	6.5	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3ccccc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL112804	9549	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	521	16	1	5	6.5	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3ccccc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10342316	57828	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	424	11	2	6	5.1	CCc1cc(-c2ccc(OC)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL167972	57828	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	424	11	2	6	5.1	CCc1cc(-c2ccc(OC)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	10363485	58779	0	None	-29	2	Human	4.4	pKi	=	4.4	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2ccc(OCc3ccc4ccccc4n3)cc2OC[C@@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	CHEMBL169743	58779	0	None	-29	2	Human	4.4	pKi	=	4.4	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2ccc(OCc3ccc4ccccc4n3)cc2OC[C@@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	9800998	98896	1	None	-32	2	Human	4.4	pKi	=	4.4	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2cc(OCc3ccc4ccccc4n3)ccc2OC[C@@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	CHEMBL282524	98896	1	None	-32	2	Human	4.4	pKi	=	4.4	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2cc(OCc3ccc4ccccc4n3)ccc2OC[C@@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	9829619	100272	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cc(Oc2ccc(C(=O)O)cc2)ccc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL292783	100272	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cc(Oc2ccc(C(=O)O)cc2)ccc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	44382463	58897	0	None	-9	2	Human	4.4	pKi	=	4.4	Binding	In vitro inhibitory activity was evaluated against leukotriene B4 (LTB4) in guinea pig binding assayIn vitro inhibitory activity was evaluated against leukotriene B4 (LTB4) in guinea pig binding assay	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2ccc(OCc3ccc4ccccc4n3)cc2OC[C@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	CHEMBL170226	58897	0	None	-9	2	Human	4.4	pKi	=	4.4	Binding	In vitro inhibitory activity was evaluated against leukotriene B4 (LTB4) in guinea pig binding assayIn vitro inhibitory activity was evaluated against leukotriene B4 (LTB4) in guinea pig binding assay	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2ccc(OCc3ccc4ccccc4n3)cc2OC[C@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	6157	2878	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Binding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligandBinding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligand	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm00070a015
	6438358	2878	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Binding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligandBinding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligand	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm00070a015
	CHEMBL422420	2878	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Binding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligandBinding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligand	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm00070a015
	6157	2878	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm00046a017
	6438358	2878	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm00046a017
	CHEMBL422420	2878	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm00046a017
	9807782	19215	0	None	-	1	Human	8.4	pKi	=	8.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	556	11	2	6	6.9	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL129463	19215	0	None	-	1	Human	8.4	pKi	=	8.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	556	11	2	6	6.9	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	9893718	204765	0	None	-	1	Human	8.4	pKi	=	8.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL292768	204765	0	None	-	1	Human	8.4	pKi	=	8.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL88337	204765	0	None	-	1	Human	8.4	pKi	=	8.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	3083459	119869	1	None	-	1	Human	8.3	pKi	=	8.3	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	412	10	2	5	5.2	CCc1cc(-c2cccc(F)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL353378	119869	1	None	-	1	Human	8.3	pKi	=	8.3	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	412	10	2	5	5.2	CCc1cc(-c2cccc(F)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	6439436	9448	2	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	536	16	2	6	6.0	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL112338	9448	2	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	536	16	2	6	6.0	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	6439436	9448	2	None	-	1	Human	8.3	pKi	=	8.3	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	536	16	2	6	6.0	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	CHEMBL112338	9448	2	None	-	1	Human	8.3	pKi	=	8.3	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	536	16	2	6	6.0	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	10292143	116084	1	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL336665	116084	1	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL48667	116084	1	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	10050724	10014	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	477	13	2	5	5.7	O=C(O)/C=C/c1nc(CSCc2cccc(C(=O)O)c2)ccc1OCCCCc1ccccc1	10.1021/jm00046a017
	CHEMBL115658	10014	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	477	13	2	5	5.7	O=C(O)/C=C/c1nc(CSCc2cccc(C(=O)O)c2)ccc1OCCCCc1ccccc1	10.1021/jm00046a017
	15839731	49171	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	430	13	2	6	4.4	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OCC(=O)O	10.1016/S0960-894X(00)80304-2
	CHEMBL15648	49171	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	430	13	2	6	4.4	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OCC(=O)O	10.1016/S0960-894X(00)80304-2
	9872540	30212	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	560	13	2	5	8.4	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1Sc1ccccc1C(=O)O	10.1021/jm00022a006
	CHEMBL139254	30212	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	560	13	2	5	8.4	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1Sc1ccccc1C(=O)O	10.1021/jm00022a006
	14977894	110105	0	None	-	1	Human	6.4	pKi	=	6.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	471	17	3	5	5.6	CCCCCCCCCCOc1ccc(CC(O)c2cccc(C(=O)O)c2)nc1CCC(=O)O	10.1021/jm00074a013
	CHEMBL325615	110105	0	None	-	1	Human	6.4	pKi	=	6.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	471	17	3	5	5.6	CCCCCCCCCCOc1ccc(CC(O)c2cccc(C(=O)O)c2)nc1CCC(=O)O	10.1021/jm00074a013
	14977961	9404	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	558	15	2	5	8.0	Nc1cccc(SCc2ccc(OCCCCCCCCc3ccc(C(F)(F)F)cc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	CHEMBL112135	9404	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	558	15	2	5	8.0	Nc1cccc(SCc2ccc(OCCCCCCCCc3ccc(C(F)(F)F)cc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	6450158	186581	14	None	-	1	Human	7.4	pKi	=	7.4	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	CHEMBL49210	186581	14	None	-	1	Human	7.4	pKi	=	7.4	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	14977916	110824	0	None	-	1	Human	6.3	pKi	=	6.3	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	515	18	2	5	6.5	CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2ccccc2C(=O)O)nc1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL326779	110824	0	None	-	1	Human	6.3	pKi	=	6.3	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	515	18	2	5	6.5	CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2ccccc2C(=O)O)nc1/C=C/C(=O)O	10.1021/jm00074a013
	10405361	14461	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	346	10	2	5	3.9	CCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1205188	14461	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	346	10	2	5	3.9	CCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL62051	14461	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	346	10	2	5	3.9	CCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	9977200	29148	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	360	11	2	5	4.3	CCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL138370	29148	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	360	11	2	5	4.3	CCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL60617	29148	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	360	11	2	5	4.3	CCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	21765772	110108	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3ccc(C(=O)O)cc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL325637	110108	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3ccc(C(=O)O)cc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	10793277	30854	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	576	13	2	5	7.4	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1[S+]([O-])c1ccccc1C(=O)O	10.1021/jm00022a006
	CHEMBL139969	30854	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	576	13	2	5	7.4	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1[S+]([O-])c1ccccc1C(=O)O	10.1021/jm00022a006
	6450158	186581	14	None	-	1	Human	8.2	pKi	=	8.2	Binding	Inhibition constant against binding of [3H]LTB4 to human neutrophilsInhibition constant against binding of [3H]LTB4 to human neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1021/jm00064a006
	CHEMBL49210	186581	14	None	-	1	Human	8.2	pKi	=	8.2	Binding	Inhibition constant against binding of [3H]LTB4 to human neutrophilsInhibition constant against binding of [3H]LTB4 to human neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1021/jm00064a006
	15658112	62829	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	419	12	2	3	6.5	CCCCCCCC[C@@H](O)c1ccc2ccc(CCc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL1788228	62829	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	419	12	2	3	6.5	CCCCCCCC[C@@H](O)c1ccc2ccc(CCc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL1789864	62829	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	419	12	2	3	6.5	CCCCCCCC[C@@H](O)c1ccc2ccc(CCc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	15658139	14392	0	None	-	1	Human	6.3	pKi	=	6.3	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	452	12	2	3	6.6	CCCCCCCCC(O)c1ccc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)cc2c1	10.1021/jm00074a012
	CHEMBL115826	14392	0	None	-	1	Human	6.3	pKi	=	6.3	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	452	12	2	3	6.6	CCCCCCCCC(O)c1ccc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)cc2c1	10.1021/jm00074a012
	CHEMBL1204497	14392	0	None	-	1	Human	6.3	pKi	=	6.3	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	452	12	2	3	6.6	CCCCCCCCC(O)c1ccc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)cc2c1	10.1021/jm00074a012
	18963028	14438	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	376	11	2	6	4.2	CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205053	14438	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	376	11	2	6	4.2	CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL47716	14438	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	376	11	2	6	4.2	CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	44382276	119797	0	None	-	1	Human	5.3	pKi	=	5.3	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL352814	119797	0	None	-	1	Human	5.3	pKi	=	5.3	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	10371282	110111	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	595	18	2	7	6.0	COc1ccc(CCCCCCCCOc2ccc(CS(=O)(=O)Cc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL325643	110111	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	595	18	2	7	6.0	COc1ccc(CCCCCCCCOc2ccc(CS(=O)(=O)Cc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	20704716	184132	0	None	-	1	Human	5.3	pKi	=	5.3	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	488	5	1	9	2.4	CN1C(=N)N(C)/C(=N/c2nc(Cc3ccc4c(c3)OCO4)c(Cc3ccc4c(c3)OCO4)n2C)C1=O	10.1021/np50100a005
	CHEMBL485054	184132	0	None	-	1	Human	5.3	pKi	=	5.3	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	488	5	1	9	2.4	CN1C(=N)N(C)/C(=N/c2nc(Cc3ccc4c(c3)OCO4)c(Cc3ccc4c(c3)OCO4)n2C)C1=O	10.1021/np50100a005
	10159791	57687	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	408	10	2	5	5.4	CCc1cc(-c2ccccc2C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL167261	57687	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	408	10	2	5	5.4	CCc1cc(-c2ccccc2C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	10046307	14612	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	374	12	2	5	4.7	CCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1206771	14612	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	374	12	2	5	4.7	CCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL305560	14612	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	374	12	2	5	4.7	CCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	19427041	14459	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	534	14	3	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL1205171	14459	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	534	14	3	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL60881	14459	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	534	14	3	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	15658149	14387	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	413	14	3	4	5.1	CCCCCCCCC(O)CCc1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a012
	CHEMBL111811	14387	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	413	14	3	4	5.1	CCCCCCCCC(O)CCc1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a012
	CHEMBL1204492	14387	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	413	14	3	4	5.1	CCCCCCCCC(O)CCc1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a012
	15658119	9703	0	None	-	1	Human	6.2	pKi	=	6.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	437	12	2	4	7.0	CCCCCCCCC(O)c1ccc2ccc(CSc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL113792	9703	0	None	-	1	Human	6.2	pKi	=	6.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	437	12	2	4	7.0	CCCCCCCCC(O)c1ccc2ccc(CSc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	14977948	9486	0	None	-	1	Human	6.2	pKi	=	6.2	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	660	19	2	7	8.2	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(NS(=O)(=O)c4ccccc4)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL112510	9486	0	None	-	1	Human	6.2	pKi	=	6.2	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	660	19	2	7	8.2	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(NS(=O)(=O)c4ccccc4)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	9845587	165066	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	408	10	2	5	5.4	CCc1cc(-c2cccc(C)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL424361	165066	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	408	10	2	5	5.4	CCc1cc(-c2cccc(C)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	10670634	57356	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	437	11	2	6	5.1	CCc1cc(-c2ccc(N(C)C)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL166862	57356	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	437	11	2	6	5.1	CCc1cc(-c2ccc(N(C)C)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	122023	50508	56	None	-	1	Human	7.2	pKi	=	7.2	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL15766	50508	56	None	-	1	Human	7.2	pKi	=	7.2	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL45460	50508	56	None	-	1	Human	7.2	pKi	=	7.2	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	10600128	57788	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	462	10	2	5	6.1	CCc1cc(-c2cccc(C(F)(F)F)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL167580	57788	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	462	10	2	5	6.1	CCc1cc(-c2cccc(C(F)(F)F)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	6435820	164453	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity against LTB4 receptors in human PMNsBinding affinity against LTB4 receptors in human PMNs	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00070a015
	CHEMBL422598	164453	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity against LTB4 receptors in human PMNsBinding affinity against LTB4 receptors in human PMNs	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00070a015
	6435820	164453	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL422598	164453	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	6435820	164453	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Compound was tested for binding affinity against Leukotriene B4 receptorCompound was tested for binding affinity against Leukotriene B4 receptor	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm960088k
	CHEMBL422598	164453	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Compound was tested for binding affinity against Leukotriene B4 receptorCompound was tested for binding affinity against Leukotriene B4 receptor	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm960088k
	6435820	164453	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	CHEMBL422598	164453	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	6444688	186727	29	None	-	1	Human	8.1	pKi	=	8.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	CHEMBL49302	186727	29	None	-	1	Human	8.1	pKi	=	8.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	6852392	17073	4	None	-	1	Human	6.2	pKi	=	6.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	361	14	3	4	4.0	CCCCC/C=C\C[C@H](O)/C=C/c1cccc(C[C@H](O)CCCCO)n1	10.1021/jm00074a012
	CHEMBL1256923	17073	4	None	-	1	Human	6.2	pKi	=	6.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	361	14	3	4	4.0	CCCCC/C=C\C[C@H](O)/C=C/c1cccc(C[C@H](O)CCCCO)n1	10.1021/jm00074a012
	14977943	114451	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	592	17	3	7	6.5	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(NC(=O)C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL334267	114451	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	592	17	3	7	6.5	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(NC(=O)C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	14977939	96256	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	505	16	1	5	7.4	COc1ccc(CCCCCCCCOc2ccc(CSc3ccccc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL264197	96256	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	505	16	1	5	7.4	COc1ccc(CCCCCCCCOc2ccc(CSc3ccccc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	15839736	14456	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	476	9	2	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1	10.1016/S0960-894X(01)80999-9
	CHEMBL1205143	14456	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	476	9	2	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1	10.1016/S0960-894X(01)80999-9
	CHEMBL58534	14456	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	476	9	2	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1	10.1016/S0960-894X(01)80999-9
	122023	50508	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80999-9
	CHEMBL15766	50508	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80999-9
	CHEMBL45460	50508	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80999-9
	122023	50508	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80304-2
	CHEMBL15766	50508	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80304-2
	CHEMBL45460	50508	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80304-2
	122023	50508	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL15766	50508	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL45460	50508	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	14977955	9470	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	548	17	1	6	7.5	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(N(C)C)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL112455	9470	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	548	17	1	6	7.5	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(N(C)C)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10257351	110140	0	None	-	1	Human	8.1	pKi	=	8.1	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	565	19	2	6	7.2	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2CCC(=O)O)cc1	10.1021/jm00046a017
	CHEMBL325773	110140	0	None	-	1	Human	8.1	pKi	=	8.1	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	565	19	2	6	7.2	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2CCC(=O)O)cc1	10.1021/jm00046a017
	9959228	9965	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	549	17	2	6	7.1	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL115362	9965	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	549	17	2	6	7.1	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	9959228	9965	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	549	17	2	6	7.1	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL115362	9965	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	549	17	2	6	7.1	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	18963062	14598	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	404	13	2	6	4.8	CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1206683	14598	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	404	13	2	6	4.8	CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL295799	14598	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	404	13	2	6	4.8	CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	10346127	9571	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	507	14	2	6	5.7	COc1ccc(CCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL112972	9571	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	507	14	2	6	5.7	COc1ccc(CCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	15658097	9628	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	401	14	3	4	5.2	CCCCCCCCC(O)c1ccc2ccc(CC(O)CCCC(=O)O)nc2c1	10.1021/jm00074a012
	CHEMBL113351	9628	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	401	14	3	4	5.2	CCCCCCCCC(O)c1ccc2ccc(CC(O)CCCC(=O)O)nc2c1	10.1021/jm00074a012
	44341265	10292	0	None	-	1	Human	5.1	pKi	=	5.1	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	263	4	2	2	3.2	Nc1nc(Cc2ccccc2)c(Cc2ccccc2)[nH]1	10.1021/jm00074a014
	CHEMBL116278	10292	0	None	-	1	Human	5.1	pKi	=	5.1	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	263	4	2	2	3.2	Nc1nc(Cc2ccccc2)c(Cc2ccccc2)[nH]1	10.1021/jm00074a014
	15658135	14389	0	None	-	1	Human	5.1	pKi	=	5.1	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	436	12	2	3	7.6	CCCCCCCCC(O)c1ccc2ccc(CSc3cccc(C(=O)O)c3)cc2c1	10.1021/jm00074a012
	CHEMBL113401	14389	0	None	-	1	Human	5.1	pKi	=	5.1	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	436	12	2	3	7.6	CCCCCCCCC(O)c1ccc2ccc(CSc3cccc(C(=O)O)c3)cc2c1	10.1021/jm00074a012
	CHEMBL1204494	14389	0	None	-	1	Human	5.1	pKi	=	5.1	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	436	12	2	3	7.6	CCCCCCCCC(O)c1ccc2ccc(CSc3cccc(C(=O)O)c3)cc2c1	10.1021/jm00074a012
	None	214434	0	3H-LTB4	3	2	Human	9.2	pKi	=	9.2	Binding	NoneNone	PDSP KiDatabase	336	14	3	3	4.2	CCCCCC=CCC(C=CC=CC=CC(CCCC(=O)O)O)O	None
	None	214437	0	3H-LTB4	-6	2	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	318	14	1	2	5.4	CCCCCC=CCC(=O)C=CC=CCC=CCCCC(=O)O	None
	None	214439	0	3H-LTB4	1	2	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	318	14	1	2	5.4	CCCCCC=CCC=CCC=CC=CC(=O)CCCC(=O)O	None
	None	214440	0	3H-LTB4	-1	2	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	320	14	2	2	5.2	CCCCCC=CCC=CCC=CC=CC(CCCC(=O)O)O	None
	None	214443	0	3H-LTB4	1	2	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	302	12	1	1	5.7	CCCCCC=CCC=CCC=CCC#CCCCC(=O)O	None
	None	214436	0	3H-LTB4	-57	2	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	320	14	2	2	5.2	CCCCCC(C=CC=CCC=CCC=CCCCC(=O)O)O	None
	None	214440	0	3H-LTB4	-1	2	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	320	14	2	2	5.2	CCCCCC=CCC=CCC=CC=CC(CCCC(=O)O)O	None
	None	214441	0	3H-LTB4	-10	2	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	320	15	2	2	5.2	C(CCC=CCC=CCC=CCC=CCCCC(=O)O)CCO	None
	None	214442	0	3H-LTB4	-10	2	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	320	14	2	2	5.2	CCCCCC=CCC=CC=CC(CC=CCCCC(=O)O)O	None
	None	214445	0	3H-LTB4	-4365	4	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	473	7	2	3	7.9	CC(C)(C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)S)O	None
	None	214450	0	3H-LTB4	1	2	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	332	13	0	3	5.3	CCCCCC=CCC=CC=CC=CC1C(O1)CCCC(=O)OC	None
	132191096	214444	0	3H-LTB4	-1	2	Human	5.8	pKi	=	5.8	Binding	NoneNone	PDSP KiDatabase	352	14	4	4	3.1	CCCCCC(C=CC=CC=CC=CC(C(CCCC(=O)O)O)O)O	None
	None	214446	0	3H-LTB4	4	2	Human	5.7	pKi	=	5.7	Binding	NoneNone	PDSP KiDatabase	625	25	7	8	2.8	CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N	None
	None	214448	0	3H-LTB4	2	2	Human	5.6	pKi	=	5.6	Binding	NoneNone	PDSP KiDatabase	439	18	4	5	4.3	CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)O)N	None
	None	214438	0	3H-LTB4	218	2	Human	7.6	pKi	=	7.6	Binding	NoneNone	PDSP KiDatabase	361	14	3	4	4.0	CCCCCC=CCC(C=CC1=NC(=CC=C1)CC(CCCCO)O)O	None
	None	214435	0	3H-LTB4	2	2	Human	8.4	pKi	=	8.4	Binding	NoneNone	PDSP KiDatabase	334	13	3	3	3.9	CCC=CCC=CCC(C=CC=CC=CC(CCCC(=O)O)O)O	None
	None	214447	0	3H-LTB4	2	2	Human	5.4	pKi	=	5.4	Binding	NoneNone	PDSP KiDatabase	496	20	5	6	3.4	CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)NCC(=O)O)N	None
	None	214449	0	3H-LTB4	1	2	Human	5.2	pKi	=	5.2	Binding	NoneNone	PDSP KiDatabase	568	23	6	7	3.7	CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)O)NC(=O)CCC(C(=O)O)N	None
	2855	4056	100	3H-LTB4	-147	6	Human	5.2	pKi	=	5.2	Binding	NoneNone	PDSP KiDatabase	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	3322	4056	100	3H-LTB4	-147	6	Human	5.2	pKi	=	5.2	Binding	NoneNone	PDSP KiDatabase	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	5717	4056	100	3H-LTB4	-147	6	Human	5.2	pKi	=	5.2	Binding	NoneNone	PDSP KiDatabase	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	CHEMBL603	4056	100	3H-LTB4	-147	6	Human	5.2	pKi	=	5.2	Binding	NoneNone	PDSP KiDatabase	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	DB00549	4056	100	3H-LTB4	-147	6	Human	5.2	pKi	=	5.2	Binding	NoneNone	PDSP KiDatabase	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	3325	3829	0	None	-	1	Human	6.4	pKi	=	6.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	361	14	3	4	4.0	CCCCC/C=C\C[C@H](/C=C/c1cccc(n1)C[C@H](CCCCO)O)O	10513580
	6449854	3829	0	None	-	1	Human	6.4	pKi	=	6.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	361	14	3	4	4.0	CCCCC/C=C\C[C@H](/C=C/c1cccc(n1)C[C@H](CCCCO)O)O	10513580
	3351	2360	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	UnclassifiedUnclassified	Guide to Pharmacology	360	10	2	6	3.6	CCc1c(OCCCCCC(c2nnn[nH]2)(C)C)cc(cc1C(=O)C)O	1659282
	35025716	2360	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	UnclassifiedUnclassified	Guide to Pharmacology	360	10	2	6	3.6	CCc1c(OCCCCCC(c2nnn[nH]2)(C)C)cc(cc1C(=O)C)O	1659282
	3405	11	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	UnclassifiedUnclassified	Guide to Pharmacology	320	14	2	2	5.2	CCCCC/C=C\C[C@H](/C=C/C=C\C/C=C\CCCC(=O)O)O	9177352
	5283156	11	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	UnclassifiedUnclassified	Guide to Pharmacology	320	14	2	2	5.2	CCCCC/C=C\C[C@H](/C=C/C=C\C/C=C\CCCC(=O)O)O	9177352
	CHEMBL1435825	11	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	UnclassifiedUnclassified	Guide to Pharmacology	320	14	2	2	5.2	CCCCC/C=C\C[C@H](/C=C/C=C\C/C=C\CCCC(=O)O)O	9177352
	177941	1551	40	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	2948	1551	40	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	CHEMBL329123	1551	40	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	DB12850	1551	40	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	114999	3469	15	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	7786309
	6156	3469	15	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	7786309
	CHEMBL14823	3469	15	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	7786309
	3399	42	0	None	-	1	Human	8.1	pKi	=	8.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology	352	15	4	4	3.1	OCCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	9177352
	5280745	42	0	None	-	1	Human	8.1	pKi	=	8.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology	352	15	4	4	3.1	OCCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	9177352
	CHEMBL1593789	42	0	None	-	1	Human	8.1	pKi	=	8.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology	352	15	4	4	3.1	OCCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	9177352
	6155	1149	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	9823886	1149	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	CHEMBL301829	1149	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	DB13053	1149	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	6157	2878	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	1332129
	6438358	2878	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	1332129
	CHEMBL422420	2878	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	1332129
	6154	627	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	11259574
	6154	627	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	17170051
	9956189	627	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	11259574
	9956189	627	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	17170051
	2487	2326	32	None	31	2	Human	9.4	pKi	=	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	None
	5280492	2326	32	None	31	2	Human	9.4	pKi	=	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	None
	CHEMBL65061	2326	32	None	31	2	Human	9.4	pKi	=	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	None
	DB12961	2326	32	None	31	2	Human	9.4	pKi	=	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	None
	2855	4056	100	None	-147	6	Human	8.3	pKi	None	8.3	Binding	NoneNone	Drug Central	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	3322	4056	100	None	-147	6	Human	8.3	pKi	None	8.3	Binding	NoneNone	Drug Central	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	5717	4056	100	None	-147	6	Human	8.3	pKi	None	8.3	Binding	NoneNone	Drug Central	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	CHEMBL603	4056	100	None	-147	6	Human	8.3	pKi	None	8.3	Binding	NoneNone	Drug Central	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	DB00549	4056	100	None	-147	6	Human	8.3	pKi	None	8.3	Binding	NoneNone	Drug Central	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None

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